Human CRYGC Recombinant Protein – Cat# MBS144337

Crystallin, Gamma C (CRYGC) Human Recombinant Protein

Name: CRYGC Recombinant Protein; Crystallin, Gamma C; Human; MyBioSource
Brand: MyBioSource
SKU: MBS144337
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS144337

Description: CRYGC Human Recombinant produced in E Coli is a single polypeptide chain containing 198 amino acids (1-174) and having a molecular mass of 23.5kDa.CRYGC is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic… More details

$250 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Crystallin, Gamma C (CRYGC), Recombinant Protein

Full Product Name

Recombinant Human Crystallin, Gamma C

Product Gene Name

CRYGC recombinant protein

Product Synonym Names

CRYGC Human; Crystallin, Gamma C Human Recombinant; Crystallin; gamma C; Gamma-crystallin 2-1; Gamma-crystallin 3; CRYG3; CCL

Sequence

MGSSHHH HHH SSGLVPRGSH MGSHMG KITF YEDRAFQGRS YETTTDCPNL QPYFSRCNSI RVESGCWMLY ERPNYQGQQY LLRRGEYPDY QQWMGLSDSI RSCCLIPQTV SHRLRLYERE DHKGLMMELS EDCPSIQDRF HLSEIRSLHV LEGCWVLYEL PNYRGRQYLL RPQEYRRCQD WGAMDAKAGS LRRVVDLY

Host

E Coli

Form/Format

The CRYGC solution (1mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 200mM NaCl, 2mM DTT and 10% glycerol.
Sterile Filtered colorless solution.

Purity/Purification

Greater than 95% as determined by SDS-PAGE.

Molecular Weight

20,879 Da

OMIM

123680

3D Structure

ModBase 3D Structure for P07315

Product Categories/Family for CRYGC recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins; Crystallin

Other Notes

Small volumes of CRYGC recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CRYGC purchase

MBS144337 is a recombinant protein targeting CRYGC. Also known as Recombinant Human Crystallin, Gamma C. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for CRYGC. It may not necessarily be applicable to this product.

NCBI GI #

10518338

NCBI GeneID

1420

NCBI Accession #

NP_066269.1

UniProt Primary Accession #

P07315

UniProt Secondary Accession #

Q53R50

UniProt Related Accession #

P07315

GenBank Nucleotide #

NM_020989.3

NCBI Official Full Name

gamma-crystallin C

NCBI Official Synonym Full Names

crystallin, gamma C

NCBI Official Symbol

CRYGC

NCBI Official Synonym Symbols

CCL; CRYG3; CTRCT2

UniProt Protein Name

Gamma-crystallin C

UniProt Synonym Protein Names

Gamma-C-crystallin; Gamma-crystallin 2-1; Gamma-crystallin 3

Protein Family

Gamma-crystallin

UniProt Gene Name

CRYGC

UniProt Synonym Gene Names

CRYG3

UniProt Entry Name

CRGC_HUMAN

NCBI Protein Information

gamma-crystallin C; gamma-crystallin 2-1; gamma-crystallin 3

NCBI Summary for CRYGC

This gene encodes a member of the beta/gamma-crystallin family of proteins. Crystallins constitute the major proteins of vertebrate eye lens and maintain the transparency and refractive index of the lens. This gene and several family members are present in a gene cluster on chromosome 2. Mutations in this gene have been shown to cause multiple types of cataract, including Coppock-like cataract and zonular pulverulent cataract, among others. [provided by RefSeq, Jan 2015]

UniProt Comments for CRYGC

CRYGC: a major structural protein of the eye lens. A member of the beta/gamma-crystallin family. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. Gamma-crystallins are involved in cataract formation.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 2q33.3

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding; structural constituent of eye lens

Biological Process: camera-type eye development; visual perception

Disease: Cataract 2, Multiple Types

Research Articles on CRYGC

1. Exome sequencing in developmental eye disease leads to identification of causal variants in GJA8, CRYGC, PAX6 and CYP1B1.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CRYGC recombinant protein

Reference Product	PubMed Publications
CRYAA recombinant protein	>22 publications with CRYGC and CRYAA
CRYBB2 recombinant protein	>15 publications with CRYGC and CRYBB2
CRYAB recombinant protein	>13 publications with CRYGC and CRYAB
BFSP2 recombinant protein	>5 publications with CRYGC and BFSP2

Diseases associated with CRYGC recombinant protein

Disease Name	Pubmed Publications
Cataract Antibodies	>45 publications with CRYGC and Cataract
Eye Abnormalities Antibodies	>3 publications with CRYGC and Eye Abnormalities

Organs/Tissues associated with CRYGC recombinant protein

Organ/Tissue Name	Pubmed Publications
Eye Antibodies	>29 publications with CRYGC and Eye