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Nudix Type Motif 10 (NUDT10) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS144338

Description: NUDT10 produced in E Coli is a single, non-glycosylated polypeptide chain containing 172 amino acids (1-164 a.a.) and having a molecular mass of 19.5kDa.NUDT10 is fused to an 8 amino acid His-tag at C-terminus & purified by proprietary… More details

$250 / 0.005 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Nudix Type Motif 10 (NUDT10), Recombinant Protein
Full Product Name
Recombinant Human Nudix Type Motif 10
Product Synonym Names
NUDT10 Human; Nudix Type Motif 10 Human Recombinant; Diphosphoinositol polyphosphate phosphohydrolase 3-alpha; DIPP-3-alpha; DIPP3-alpha; hDIPP3alpha; Diadenosine 5'; 5'''-P1; P6-hexaphosphate hydrolase 3-alpha; Nucleoside diphosphate-linked moiety X motif 10; Nudix motif 10; hAps2; NUDT10; APS2; DIPP3A
Sequence
MKCKPNQTRT YDPEGFKKRA ACLCFRSERE DEVLLVSSSR YPDRWIVPGG GMEPEEEPGG AAVREVYEEA GVKGKLGRLL GVFEQNQDPK HRTYVYVLTV TELLEDWEDS VSIGRKREWF KVEDAIKVLQ CHKPVHAEYL EKLKLGGSPT NGNSMAPSSP DSDPLEH HHH HH
Host
E Coli
Form/Format
NUDT10 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl and 1mM DTT.
Sterile Filtered colorless solution.
Purity/Purification
Greater than 95.0% as determined by SDS-PAGE.
Preparation and Storage
NUDT10 Human Recombinant although stable at 4 degree C for 1 week, should be stored below -18 degree C. Please prevent freeze thaw cycles.
Molecular Weight
18,500 Da
OMIM
300527
3D Structure
ModBase 3D Structure for Q8NFP7

Other Notes

Small volumes of NUDT10 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NUDT10 purchase

MBS144338 is a recombinant protein targeting NUDT10. Also known as Recombinant Human Nudix Type Motif 10. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for NUDT10. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
diphosphoinositol polyphosphate phosphohydrolase 3-alpha
NCBI Official Synonym Full Names
nudix (nucleoside diphosphate linked moiety X)-type motif 10
NCBI Official Symbol
NUDT10
NCBI Official Synonym Symbols
APS2; DIPP3a; DIPP3-alpha
UniProt Protein Name
Diphosphoinositol polyphosphate phosphohydrolase 3-alpha
UniProt Synonym Protein Names
Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 3-alpha; Diadenosine hexaphosphate hydrolase (AMP-forming) (EC:3.6.1.60); Nucleoside diphosphate-linked moiety X motif 10; Nudix motif 10; hAps2
UniProt Gene Name
NUDT10
UniProt Synonym Gene Names
APS2; DIPP3A; DIPP-3-alpha; DIPP3-alpha; hDIPP3alpha; Nudix motif 10
UniProt Entry Name
NUD10_HUMAN
NCBI Protein Information
diphosphoinositol polyphosphate phosphohydrolase 3-alpha; diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 3-alpha; diadenosine hexaphosphate hydrolase (AMP-forming); nucleoside diphosphate-linked moiety X motif 10; nudix motif 10

NCBI Summary for NUDT10

This gene is a member of the nudix (nucleoside diphosphate linked moiety X)-type motif containing family. The encoded protein is a phosphohydrolase and may regulate the turnover of diphosphoinositol polyphosphates. The turnover of these high-energy diphosphoinositol polyphosphates represents a molecular switching activity with important regulatory consequences. Molecular switching by diphosphoinositol polyphosphates may contribute to the regulation of intracellular trafficking. In some populations putative prostate cancer susceptibility alleles have been identified for this gene. Alternatively spliced transcript variants, which differ only in the 5' UTR, have been found for this gene. [provided by RefSeq, Feb 2015]
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UniProt Comments for NUDT10

NUDT10: Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate. Belongs to the Nudix hydrolase family. DIPP subfamily.

Protein type: EC 3.6.1.52; EC 3.6.1.60; Hydrolase

Chromosomal Location of Human Ortholog: Xp11.23

Cellular Component: cytosol

Molecular Function: metal ion binding; diphosphoinositol-polyphosphate diphosphatase activity

Biological Process: inositol phosphate metabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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