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Vacuolar Protein Sorting 29 (mVPS29) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS144374

Description: VPS29 Mouse Recombinant produced in E Coli is a single polypeptide chain containing 207 amino acids (1-182) and having a molecular mass of 23.2kDa.VPS29 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic… More details

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Product Overview

Online Datasheet in PDF
Product Name
Vacuolar Protein Sorting 29 (mVPS29), Recombinant Protein
Full Product Name
Recombinant Mouse Vacuolar Protein Sorting 29
Product Gene Name
mVPS29 recombinant protein
Product Synonym Names
VPS29 Mouse; Vacuolar Protein Sorting 29 Mouse Recombinant; Vacuolar protein sorting 29 yeast homolog (S. cerevisiae); DC15; PEP11; DC7; retromer protein; x 007 protein; EC 3.1.3.3
Sequence
MGSSHHH HHH SSGLVPRGSH MGSHMM LVLV LGDLHIPHRC NSLPAKFKKL LVPGKIQHIL CTGNLCTKES YDYLKTLAGD VHIVRGDFDE NLNYPEQKVV TVGQFKIGLI HGHQVIPWGD MASLALLQRQ FDVDILISGH THKFEAFEHE NKFYINPGSA TGAYNALETN IIPSFVLMDI QASTVVTYVY QLIGDDVKVE RIEYKKS
Host
E Coli
Form/Format
The VPS29 solution (0.5mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 100mM Nacl, 1mM DTT and 10% glycerol.
Sterile Filtered colorless solution.
Purity/Purification
Greater than 95% as determined by SDS-PAGE.
Molecular Weight
20,917 Da
3D Structure
ModBase 3D Structure for Q9QZ88

Product Categories/Family for mVPS29 recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins; Vacuolar Protein Sorting

Other Notes

Small volumes of mVPS29 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for mVPS29 purchase

MBS144374 is a recombinant protein targeting mVPS29. Also known as Recombinant Mouse Vacuolar Protein Sorting 29. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for mVPS29. It may not necessarily be applicable to this product.

NCBI GI #
9790285
NCBI GeneID
56433
NCBI Accession #
NP_062754.1
UniProt Primary Accession #
Q9QZ88
UniProt Secondary Accession #
Q3UCZ0; Q9D107
UniProt Related Accession #
Q9QZ88
GenBank Nucleotide #
NM_019780.1
NCBI Official Full Name
vacuolar protein sorting-associated protein 29
NCBI Official Synonym Full Names
vacuolar protein sorting 29 (S. pombe)
NCBI Official Symbol
Vps29
NCBI Official Synonym Symbols
PEP11; AW049835; 2010015D08Rik
UniProt Protein Name
Vacuolar protein sorting-associated protein 29
UniProt Synonym Protein Names
Vesicle protein sorting 29
UniProt Gene Name
Vps29
UniProt Entry Name
VPS29_MOUSE
NCBI Protein Information
vacuolar protein sorting-associated protein 29; vacuolar sorting protein 29; vesicle protein sorting 29

UniProt Comments for mVPS29

VPS29: Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro). Belongs to the VPS29 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Protein phosphatase, Ser/Thr (non-receptor); Vesicle; EC 3.1.3.3

Cellular Component: intracellular membrane-bound organelle; membrane; cell; retromer complex; cytoplasm; intracellular; endosome

Molecular Function: zinc ion binding; metal ion binding; protein transporter activity

Biological Process: intracellular protein transport; protein transport; transport; Golgi to vacuole transport; retrograde transport, endosome to Golgi
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Research Articles on mVPS29

1. These results suggest that mouse Vps26b-Vps29-Vps35 retromer complex is implicated in the transport of sortilin from endosomes to the trans-Golgi network.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with mVPS29 recombinant protein

 Products by Pathway  Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By WNT In Cancer Pathway antibodies  Signaling By WNT In Cancer Pathway Diagram
 Signaling By Wnt Pathway antibodies  Signaling By Wnt Pathway Diagram
 WNT Ligand Biogenesis And Trafficking Pathway antibodies  WNT Ligand Biogenesis And Trafficking Pathway Diagram
 WNT Ligand Secretion Is Abrogated By The PORCN Inhibitor LGK974 Pathway antibodies  WNT Ligand Secretion Is Abrogated By The PORCN Inhibitor LGK974 Pathway Diagram
 Serine Biosynthesis Pathway antibodies  Serine Biosynthesis Pathway Diagram
 Superpathway Of Serine And Glycine Biosynthesis I antibodies  Superpathway Of Serine And Glycine Biosynthesis I Diagram

Diseases associated with mVPS29 recombinant protein

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >5 publications with mVPS29 and Nervous System Diseases
 Brain Diseases Antibodies  >3 publications with mVPS29 and Brain Diseases
 Kidney Diseases Antibodies  >3 publications with mVPS29 and Kidney Diseases
 Death Antibodies  >1 publications with mVPS29 and Death

Organs/Tissues associated with mVPS29 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >5 publications with mVPS29 and Kidney
 Brain Antibodies  >3 publications with mVPS29 and Brain
 Muscle Antibodies  >1 publications with mVPS29 and Muscle
 Testis Antibodies  >1 publications with mVPS29 and Testis
 Liver Antibodies  >1 publications with mVPS29 and Liver
 Embryonic Tissue Antibodies  >1 publications with mVPS29 and Embryonic Tissue
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