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Thioredoxin-Like 4a (TXNL4A) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS144377

Description: TXNL4A Human Recombinant produced in E Coli is a single polypeptide chain containing 166 amino acids (1-142) and having a molecular mass of 19.3kDa.TXNL4A is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic… More details

$250 / 0.002 mg +1 FREE 8GB USB
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Thioredoxin-Like 4A (TXNL4A), Recombinant Protein
Full Product Name
Recombinant Human Thioredoxin-Like 4A
Product Synonym Names
TXNL4A Human; Thioredoxin-Like 4A Human Recombinant; Thioredoxin-like 4A; Spliceosomal U5 snRNP-specific 15 kDa protein; DIM1 protein homolog; HsT161; TXNL4; DIB1; U5-15kD
Sequence
MGSSHHH HHH SSGLVPRGSH MGSHMS YMLP HLHNGWQVDQ AILSEEDRVV VIRFGHDWDP TCMKMDEVLY SIAEKVKNFA VIYLVDITEV PDFNKMYELY DPCTVMFFFR NKHIMIDLGT GNNNKINWAM EDKQEMVDII ETVYRGARKG RGLVVSPKDY STKYRY
Host
E Coli
Form/Format
The TXNL4A solution (0.5mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 200mM NaCl and 20% glycerol.
Sterile Filtered colorless solution.
Purity/Purification
Greater than 95% as determined by SDS-PAGE.
Molecular Weight
16,786 Da
OMIM
611595
3D Structure
ModBase 3D Structure for P83876

Other Notes

Small volumes of TXNL4A recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TXNL4A purchase

MBS144377 is a recombinant protein targeting TXNL4A. Also known as Recombinant Human Thioredoxin-Like 4A. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for TXNL4A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
thioredoxin-like protein 4A isoform 1
NCBI Official Synonym Full Names
thioredoxin-like 4A
NCBI Official Symbol
TXNL4A
NCBI Official Synonym Symbols
BMKS; DIB1; DIM1; TXNL4; SNRNP15; U5-15kD
UniProt Protein Name
Thioredoxin-like protein 4A
UniProt Synonym Protein Names
DIM1 protein homolog; Spliceosomal U5 snRNP-specific 15 kDa protein; Thioredoxin-like U5 snRNP protein U5-15kD
UniProt Gene Name
TXNL4A
UniProt Synonym Gene Names
DIM1; TXNL4
UniProt Entry Name
TXN4A_HUMAN
NCBI Protein Information
thioredoxin-like protein 4A; DIM1 protein homolog; spliceosomal U5 snRNP-specific 15 kDa protein; thioredoxin-like 4; thioredoxin-like U5 snRNP protein U5-15kD

NCBI Summary for TXNL4A

The protein encoded by this gene is a member of the U5 small ribonucleoprotein particle (snRNP), and is involved in pre-mRNA splicing. This protein contains a thioredoxin-like fold and it is expected to interact with multiple proteins. Protein-protein interactions have been observed with the polyglutamine tract-binding protein 1 (PQBP1). Mutations in both the coding region and promoter region of this gene have been associated with Burn-McKeown syndrome, which is a rare disorder characterized by craniofacial dysmorphisms, cardiac defects, hearing loss, and bilateral choanal atresia. A pseudogene of this gene is found on chromosome 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2015]
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UniProt Comments for TXNL4A

TXNL4A: Essential role in pre-mRNA splicing. Belongs to the DIM1 family.

Protein type: RNA-binding; Spliceosome

Chromosomal Location of Human Ortholog: 18q23

Cellular Component: nucleoplasm; spliceosome; U4/U6 x U5 tri-snRNP complex; snRNP U5

Molecular Function: protein binding

Biological Process: nuclear mRNA splicing, via spliceosome; RNA splicing, via transesterification reactions; mitosis; cell division; RNA splicing; spliceosome assembly; gene expression

Disease: Burn-mckeown Syndrome
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with TXNL4A recombinant protein

 Reference Product  PubMed Publications
 EFTUD2 recombinant protein  >1 publications with TXNL4A and EFTUD2

Organs/Tissues associated with TXNL4A recombinant protein

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