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MAD2L1 (MAD2L1BP) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS144425

Description: MAD2L1BP Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 298 amino acids (1-274 a.a) and having a molecular mass of 33.6kDa (Molecular weight on SDS-PAGE will appear higher).MAD2L1BP is fused to a… More details

$250 / 0.002 mg +1 FREE 8GB USB
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
MAD2L1 (MAD2L1BP), Recombinant Protein
Full Product Name
Recombinant Human MAD2L1 Binding Protein
Product Synonym Names
MAD2L1BP Human; MAD2L1 Binding Protein Human Recombinant; MAD2L1-binding protein; Caught by MAD2 protein; MAD2L1BP; CMT2; KIAA0110; RP1-261G23.6
Sequence
MGSSHHH HHH SSGLVPRGSH MGSHMA APEA EVLSSAAVPD LEWYEKSEET HASQIELLET SSTQEPLNAS EAFCPRDCMV PVVFPGPVSQ EGCCQFTCEL LKHIMYQRQQ LPLPYEQLKH FYRKPSPQAE EMLKKKPRAT TEVSSRKCQQ ALAELESVLS HLEDFFARTL VPRVLILLGG NALSPKEFYE LDLSLLAPYS VDQSLSTAAC LRRLFRAIFM ADAFSELQAP PLMGTVVMAQ GHRNCGEDWF RPKLNYRVPS RGHKLTVTLS CGRPSIRTTA WEDYIWFQAP VTFKGFRE.< /u>
Host
E Coli
Form/Format
MAD2L1BP protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 10% glycerol and 100mM NaCl.
Sterile Filtered clear solution.
Purity/Purification
Greater than 90.0% as determined by SDS-PAGE.
Molecular Weight
34,676 Da
3D Structure
ModBase 3D Structure for Q15013

Other Notes

Small volumes of MAD2L1BP recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MAD2L1BP purchase

MBS144425 is a recombinant protein targeting MAD2L1BP. Also known as Recombinant Human MAD2L1 Binding Protein. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for MAD2L1BP. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
MAD2L1-binding protein isoform 1
NCBI Official Synonym Full Names
MAD2L1 binding protein
NCBI Official Symbol
MAD2L1BP
NCBI Official Synonym Symbols
CMT2
UniProt Protein Name
MAD2L1-binding protein
UniProt Synonym Protein Names
Caught by MAD2 protein
UniProt Gene Name
MAD2L1BP
UniProt Synonym Gene Names
CMT2; KIAA0110
UniProt Entry Name
MD2BP_HUMAN
NCBI Protein Information
MAD2L1-binding protein; caught by MAD2 protein

NCBI Summary for MAD2L1BP

The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
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UniProt Comments for MAD2L1BP

MAD2L1BP: May function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex. Belongs to the MAD2L1BP family.

Protein type: Cell cycle regulation

Chromosomal Location of Human Ortholog: 6p21.1

Cellular Component: intracellular membrane-bound organelle; cytoplasm; nucleolus; spindle; nucleus

Molecular Function: protein binding

Biological Process: mitotic cell cycle checkpoint; regulation of exit from mitosis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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