Mouse mS100A1 Recombinant Protein – Cat# MBS144426

S100 Calcium Binding Protein A1 (mS100A1) Mouse Recombinant Protein

Name: mS100A1 Recombinant Protein; Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS144426
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS144426

Description: S100A1 produced in E Coli is a single, non-glycosylated polypeptide chain containing 114 amino acids (1-94 a.a) and having a molecular mass of 12.6kDa (molecular weight on SDS-PAGE will appear higher).S100A1 is fused to a 20 amino acid His-tag at… More details

$250 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

S100 Calcium Binding Protein A1 (mS100A1), Recombinant Protein

Full Product Name

Recombinant Mouse S100 Calcium Binding Protein A1

Product Gene Name

mS100A1 recombinant protein

Product Synonym Names

S100A1 Mouse; S100 Calcium Binding Protein A1 Mouse Recombinant; Protein S100-A1; S-100 protein alpha chain; S-100 protein subunit alpha; S100 calcium-binding protein A1; S100a1; S100; S100a; AI266795

Sequence

MGSSHHH HHH SSGLVPRGSH MGSELESAME TLINVFHAHS GKEGDKYKLS KKELKDLLQT ELSGFLDVQK DADAVDKVMK ELDENGDGEV DFKEYVVLVA ALTVACNNFF WETS

Host

E Coli

Form/Format

S100A1 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 30% glycerol and 0.1M NaCl.
Sterile Filtered clear solution.

Purity/Purification

Greater than 90.0% as determined by SDS-PAGE.

Preparation and Storage

S100A1 Mouse Recombinant although stable at 4 degree C for 1 week, should be stored below -18 degree C. Please prevent freeze thaw cycles.

Molecular Weight

10,505 Da

3D Structure

ModBase 3D Structure for P56565

Product Categories/Family for mS100A1 recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins; Calcium Binding Protein

Other Notes

Small volumes of mS100A1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for mS100A1 purchase

MBS144426 is a recombinant protein targeting mS100A1. Also known as Recombinant Mouse S100 Calcium Binding Protein A1. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for mS100A1. It may not necessarily be applicable to this product.

NCBI GI #

6755386

NCBI GeneID

20193

NCBI Accession #

NP_035439.1

UniProt Primary Accession #

P56565

UniProt Secondary Accession #

O88949

UniProt Related Accession #

P56565

GenBank Nucleotide #

NM_011309.3

NCBI Official Full Name

protein S100-A1

NCBI Official Synonym Full Names

S100 calcium binding protein A1

NCBI Official Symbol

S100a1

NCBI Official Synonym Symbols

S100; S100a; AI266795

UniProt Protein Name

Protein S100-A1

UniProt Synonym Protein Names

S-100 protein alpha chain; S-100 protein subunit alpha; S100 calcium-binding protein A1

Protein Family

Sentan

UniProt Gene Name

S100a1

UniProt Entry Name

S10A1_MOUSE

NCBI Protein Information

protein S100-A1; S-100 protein alpha chain; S-100 protein subunit alpha; S100 calcium-binding protein A1

UniProt Comments for mS100A1

S100A1: Weakly binds calcium but binds zinc very tightly- distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Dimer of either two alpha chains, or two beta chains, or one alpha and one beta chain. Interacts with AGER and CAPZA1. Interacts with FKBP4. Interacts with RYR1 and RYR2. Highly prevalent in heart. Also found in lesser quantities in skeletal muscle and brain. Belongs to the S-100 family.

Protein type: Calcium-binding; Endoplasmic reticulum

Cellular Component: I band; neuron projection; sarcoplasmic reticulum; cytoplasm; M band; nucleus; Z disc; A band

Molecular Function: identical protein binding; protein binding; protein homodimerization activity; metal ion binding; calcium ion binding; calcium-dependent protein binding; ATPase binding

Biological Process: negative regulation of transcription from RNA polymerase II promoter; regulation of heart contraction

Research Articles on mS100A1

1. Patients with acute myocardial infarction (MI) showed significantly increased S100A1 serum levels. Experimental MI in mice induced comparable S100A1 release. S100A1 signaling in cardiac fibroblasts occurs through endosomal TLR4/MyD88.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with mS100A1 recombinant protein

Disease Name	Pubmed Publications
Cardiovascular Diseases Antibodies	>50 publications with mS100A1 and Cardiovascular Diseases
Heart Diseases Antibodies	>44 publications with mS100A1 and Heart Diseases
Ischemia Antibodies	>17 publications with mS100A1 and Ischemia
Hypertrophy Antibodies	>16 publications with mS100A1 and Hypertrophy
Kidney Diseases Antibodies	>16 publications with mS100A1 and Kidney Diseases
Disease Models, Animal Antibodies	>16 publications with mS100A1 and Disease Models, Animal
Neoplasm Metastasis Antibodies	>15 publications with mS100A1 and Neoplasm Metastasis
Inflammation Antibodies	>10 publications with mS100A1 and Inflammation
Breast Neoplasms Antibodies	>9 publications with mS100A1 and Breast Neoplasms
Hypertension Antibodies	>6 publications with mS100A1 and Hypertension

Organs/Tissues associated with mS100A1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>101 publications with mS100A1 and Muscle
Heart Antibodies	>80 publications with mS100A1 and Heart
Brain Antibodies	>62 publications with mS100A1 and Brain
Blood Antibodies	>52 publications with mS100A1 and Blood
Skin Antibodies	>28 publications with mS100A1 and Skin
Kidney Antibodies	>21 publications with mS100A1 and Kidney
Embryonic Tissue Antibodies	>10 publications with mS100A1 and Embryonic Tissue
Lung Antibodies	>10 publications with mS100A1 and Lung
Joint Antibodies	>8 publications with mS100A1 and Joint
Intestine Antibodies	>7 publications with mS100A1 and Intestine