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Nucleophosmin 2 (NPM2) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS144440

Description: NPM2 Human Recombinant produced in E Coli is a single polypeptide chain containing 237 amino acids (1-214) and having a molecular mass of 26.6 kDa.NPM2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic… More details

$250 / 0.002 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Nucleophosmin 2 (NPM2), Recombinant Protein
Full Product Name
Recombinant Human Nucleophosmin 2
Product Gene Name
Product Synonym Names
NPM2 Human; Nucleophosmin 2 Human Recombinant; Nucleophosmin/nucleoplasmin 2; nucleoplasmin-2
Sequence
MGSSHHH HHH SSGLVPRGSH MGSMNL SSAS STEEKAVTTV LWGCELSQER RTWTFRPQLE GKQSCRLLLH TICLGEKAKE EMHRVEILPP ANQEDKKMQP VTIASLQASV LPMVSMVGVQ LSPPVTFQLR AGSGPVFLSG QERYEASDLT WEEEEEEEGE EEEEEEEDDE DEDADISLEE QSPVKQVKRL VPQKQASVAK KKKLEKEEEE IRASVRDKSP VKKAKATARA KKPGFKK
Host
E Coli
Form/Format
The NPM2 solution (0.5mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 200mM NaCl, 2mM DTT and 20% glycerol.
Sterile Filtered colorless solution.
Purity/Purification
Greater than 85% as determined by SDS-PAGE.
Molecular Weight
15,238 Da
OMIM
608073
3D Structure
ModBase 3D Structure for Q86SE8

Other Notes

Small volumes of NPM2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NPM2 purchase

MBS144440 is a recombinant protein targeting NPM2. Also known as Recombinant Human Nucleophosmin 2. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for NPM2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
nucleoplasmin-2 isoform 1
NCBI Official Synonym Full Names
nucleophosmin/nucleoplasmin 2
NCBI Official Symbol
NPM2
UniProt Protein Name
Nucleoplasmin-2
Protein Family
UniProt Gene Name
NPM2
UniProt Entry Name
NPM2_HUMAN
NCBI Protein Information
nucleoplasmin-2

UniProt Comments for NPM2

NPM2: Core histones chaperone involved in chromatin reprogramming, specially during fertilization and early embryonic development. Probably involved in sperm DNA decondensation during fertilization. Belongs to the nucleoplasmin family.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 8p21.3

Cellular Component: nuclear chromatin; nucleus

Molecular Function: enzyme binding; nucleic acid binding; histone binding; chromatin binding

Biological Process: positive regulation of catalytic activity; chromatin remodeling; embryonic development; positive regulation of meiosis; single fertilization; regulation of exit from mitosis; oocyte differentiation; protein homooligomerization; positive regulation of DNA replication
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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