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C-Myc (MYCBP) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS144459

Description: MYCBP Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 123 amino acids (1-103 a.a.) and having a molecular mass of 14.1kDa.MYCBP is fused to a 20 amino acid His-tag at N-terminus & purified by… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
C-Myc (MYCBP), Recombinant Protein
Full Product Name
Recombinant Human C-Myc Binding Protein
Product Gene Name
MYCBP recombinant protein
Product Synonym Names
MYCBP Human; C-Myc Binding Protein Human Recombinant; C-Myc-binding protein; Associate of Myc 1; AMY-1; MYCBP; AMY1; FLJ41056
Sequence
MGSSHHH HHH SSGLVPRGSH MAHYKAADSK REQFRRYLEK SGVLDTLTKV LVALYEEPEK PNSALDFLKH HLGAATPENP EIELLRLELA EMKEKYEAIV EENKKLKAKL AQYEPPQEEK RAE.
Host
E Coli
Form/Format
MYCBP protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl and 1mM DTT.
Sterile Filtered colorless solution.
Purity/Purification
Greater than 95.0% as determined by SDS-PAGE.
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Molecular Weight
11,967 Da
OMIM
606535
3D Structure
ModBase 3D Structure for Q99417

Product Categories/Family for MYCBP recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins

Other Notes

Small volumes of MYCBP recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MYCBP purchase

MBS144459 is a recombinant protein targeting MYCBP. Also known as Recombinant Human C-Myc Binding Protein. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for MYCBP. It may not necessarily be applicable to this product.

NCBI GI #
57242777
NCBI GeneID
26292
NCBI Accession #
NP_036465.2
UniProt Primary Accession #
Q99417
UniProt Secondary Accession #
Q5TA64; Q96HE2; B2R4N0
UniProt Related Accession #
Q99417
GenBank Nucleotide #
NM_012333.4
NCBI Official Full Name
C-Myc-binding protein
NCBI Official Synonym Full Names
MYC binding protein
NCBI Official Symbol
MYCBP
NCBI Official Synonym Symbols
AMY-1
UniProt Protein Name
C-Myc-binding protein
UniProt Synonym Protein Names
Associate of Myc 1; AMY-1
Protein Family
C-Myc-binding protein
UniProt Gene Name
MYCBP
UniProt Synonym Gene Names
AMY1; AMY-1
UniProt Entry Name
MYCBP_HUMAN
NCBI Protein Information
C-Myc-binding protein; associate of myc-1; c-myc binding protein

NCBI Summary for MYCBP

The protein encoded by this gene binds to the N-terminus of the oncogenic protein C-MYC, enhancing the ability of C-MYC to activate E box-dependent transcription. The encoded protein is normally found in the cytoplasm, but it translocates to the nucleus during S phase of the cell cycle and associates with C-MYC. This protein may be involved in spermatogenesis. This gene can be silenced by microRNA-22. Two transcript variants, one protein-coding and the other probably not protein-coding, have been found for this gene. [provided by RefSeq, Nov 2011]
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UniProt Comments for MYCBP

MYCBP: May control the transcriptional activity of MYC. Stimulates the activation of E box-dependent transcription by MYC. Belongs to the AMY1 family.

Protein type: Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 1p33-p32.2

Cellular Component: centrosome; mitochondrion; cytoplasm; nucleus

Molecular Function: protein binding; transcription coactivator activity

Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent; spermatogenesis
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Research Articles on MYCBP

1. c-Myc expression is reduced in pterygium compared with normal conjunctiva.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with MYCBP recombinant protein

 Reference Product  PubMed Publications
 MYC recombinant protein  >75 publications with MYCBP and MYC
 AKAP1 recombinant protein  >3 publications with MYCBP and AKAP1
 ARFGEF1 recombinant protein  >1 publications with MYCBP and ARFGEF1
 MYCBPAP recombinant protein  >1 publications with MYCBP and MYCBPAP
 C3orf15 recombinant protein  >1 publications with MYCBP and C3orf15

Pathways associated with MYCBP recombinant protein

 Products by Pathway  Pathway Diagram
 Notch Signaling Pathway antibodies  Notch Signaling Pathway Diagram

Diseases associated with MYCBP recombinant protein

 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >9 publications with MYCBP and Breast Neoplasms
 Neoplasm Metastasis Antibodies  >7 publications with MYCBP and Neoplasm Metastasis
 Neoplasms, Experimental Antibodies  >5 publications with MYCBP and Neoplasms, Experimental
 Liver Neoplasms Antibodies  >4 publications with MYCBP and Liver Neoplasms
 Adenocarcinoma Antibodies  >3 publications with MYCBP and Adenocarcinoma
 Hyperplasia Antibodies  >3 publications with MYCBP and Hyperplasia
 Liver Diseases Antibodies  >3 publications with MYCBP and Liver Diseases
 Prostatic Diseases Antibodies  >3 publications with MYCBP and Prostatic Diseases
 Urinary Bladder Neoplasms Antibodies  >2 publications with MYCBP and Urinary Bladder Neoplasms
 Carcinoma, Hepatocellular Antibodies  >1 publications with MYCBP and Carcinoma, Hepatocellular

Organs/Tissues associated with MYCBP recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >7 publications with MYCBP and Liver
 Bone Antibodies  >5 publications with MYCBP and Bone
 Lymph Node Antibodies  >5 publications with MYCBP and Lymph Node
 Prostate Antibodies  >5 publications with MYCBP and Prostate
 Stomach Antibodies  >4 publications with MYCBP and Stomach
 Blood Antibodies  >4 publications with MYCBP and Blood
 Bone Marrow Antibodies  >3 publications with MYCBP and Bone Marrow
 Vascular Antibodies  >3 publications with MYCBP and Vascular
 Embryonic Tissue Antibodies  >3 publications with MYCBP and Embryonic Tissue
 Testis Antibodies  >3 publications with MYCBP and Testis
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