Human URM1 Recombinant Protein – Cat# MBS144485

Ubiquitin Related Modifier 1 (URM1) Human Recombinant Protein

Name: URM1 Recombinant Protein; Ubiquitin Related Modifier 1; Human; MyBioSource
Brand: MyBioSource
SKU: MBS144485
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS144485

Description: URM1 produced in E Coli is a single, non-glycosylated polypeptide chain containing 121 amino acids (1-101 a.a.) and having a molecular mass of 13.5kDa.URM1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary… More details

$250 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Ubiquitin Related Modifier 1 (URM1), Recombinant Protein

Full Product Name

Recombinant Human Ubiquitin Related Modifier 1

Product Gene Name

URM1 recombinant protein

Product Synonym Names

URM1 Human; Ubiquitin Related Modifier 1 Human Recombinant; Ubiquitin-related modifier 1 homolog; URM1; C9orf74; MGC2668; RP11-339B21.4

Sequence

MGSSHHH HHH SSGLVPRGSH MAAPLSVEVE FGGGAELLFD GIKKHRVTLP GQEEPWDIRN LLIWIKKNLL KERPELFIQG DSVRPGILVL INDADWELLG ELDYQLQDQD SVLFISTLHG G.

Host

E Coli

Form/Format

The URM1 solution (1 mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 10% glycerol and 1mM DTT.
Sterile Filtered colorless solution.

Purity/Purification

Greater than 95.0% as determined by SDS-PAGE.

Preparation and Storage

Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

Molecular Weight

7,143 Da

OMIM

612693

3D Structure

ModBase 3D Structure for Q9BTM9

Product Categories/Family for URM1 recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins; Ubiquitin

Other Notes

Small volumes of URM1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for URM1 purchase

MBS144485 is a recombinant protein targeting URM1. Also known as Recombinant Human Ubiquitin Related Modifier 1. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for URM1. It may not necessarily be applicable to this product.

NCBI GI #

209693464

NCBI GeneID

81605

NCBI Accession #

NP_001129419.1

UniProt Primary Accession #

Q9BTM9

UniProt Secondary Accession #

Q5T4B4; B3KMH3; B4DV08

UniProt Related Accession #

Q9BTM9

GenBank Nucleotide #

NM_001135947.2

NCBI Official Full Name

ubiquitin-related modifier 1 isoform b

NCBI Official Synonym Full Names

ubiquitin related modifier 1

NCBI Official Symbol

URM1

NCBI Official Synonym Symbols

C9orf74

UniProt Protein Name

Ubiquitin-related modifier 1

Protein Family

Ubiquitin-related modifier

UniProt Gene Name

URM1

UniProt Entry Name

URM1_HUMAN

NCBI Protein Information

ubiquitin-related modifier 1; URM1; ubiquitin related modifier 1 homolog; ubiquitin-related modifier 1 homolog

UniProt Comments for URM1

URM1: Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. May also act as an ubiquitin-like protein that is covalently conjugated to other proteins; the relevance of such function is however unclear in vivo. Belongs to the URM1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transferase; Ubiquitin-like modifier

Chromosomal Location of Human Ortholog: 9q34.11

Cellular Component: cytosol

Molecular Function: sulfurtransferase activity; protein binding

Biological Process: protein urmylation; tRNA wobble uridine modification

Research Articles on URM1

1. observations suggest that Urm1 activation is more similar to that of a prokaryotic sulfur carrier protein than that of a ubiquitin-like protein

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with URM1 recombinant protein

Reference Product	PubMed Publications
MOCS3 recombinant protein	>4 publications with URM1 and MOCS3
ELP2 recombinant protein	>1 publications with URM1 and ELP2
UFM1 recombinant protein	>1 publications with URM1 and UFM1
CTU2 recombinant protein	>1 publications with URM1 and CTU2

Pathways associated with URM1 recombinant protein

Products by Pathway	Pathway Diagram
Sulfur Relay System Pathway antibodies	Sulfur Relay System Pathway Diagram
Sulfur Relay System Pathway antibodies	Sulfur Relay System Pathway Diagram

Diseases associated with URM1 recombinant protein

Disease Name	Pubmed Publications
Weight Gain Antibodies	>1 publications with URM1 and Weight Gain