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Cell Division Cycle Protein 20 Homolog (CDC20) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1444892

CDC20 appears to act as a regulatory protein interacting with several other proteins at multiple points in the cell cycle. It is required for two microtubule-dependent processes, nuclear movement prior to anaphase and chromosome separation. More details

$1300 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Cell division cycle protein 20 homolog (Cdc20), Recombinant Protein
Full Product Name
Recombinant Mouse Cell division cycle protein 20 homolog (Cdc20)
Product Gene Name
Cdc20 recombinant protein
Product Synonym Gene Name
Cdc20
Sequence
MAQFVFESDL HSLLQLDAPI PNAPVARWQR KAKEATGPAP SPMRAANRSH SAGRTPGRTP GKSSSKVQTT PSKPGGDRFI PQRSASQMEV ASFLLSKENQ PEDRGTPTKK EHQKAWSLNL NGFDVEEAKI LRLSGKPQNA PEGYQNRLKV LYSQKATPGS SRKTCRYIPS LPDRILDAPE IRNDYYLNLV DWSSGNVLAV ALDNSVYLWN AGSGDILQLL QMEQPGDYIS SVAWIKEGNY LAVGTSNAEV QLWDVQQQKR LRNMTSHSAR VSSLSWNSYI LSSGSRSGHI HHHDVRVAEH HVATLSGHSQ EVCGLRWAPD GRHLASGGND NIVNVWPSGP GESGWAPLQT FTQHQGAVKA VAWCPWQSNI LATGGGTSDR HIRIWNVCSG ACLSAVDVHS QVCSILWSPH YKELISGHGF AQNQLVIWKY PTMAKVAELK GHTARVLGLT MSPDGATVAS AAADETLRLW RCFEMDPALR REREKASVAK SSLIHQGIR
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
54,816 Da
Sequence Positions
1-499, full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q9JJ66
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Cdc20 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Cdc20 purchase

MBS1444892 is a recombinant protein targeting Cdc20. Also known as Recombinant Mouse Cell division cycle protein 20 homolog (Cdc20). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Cdc20. It may not necessarily be applicable to this product.

NCBI GI #
165377264
NCBI GeneID
107995
NCBI Accession #
NP_075712.2
UniProt Primary Accession #
Q9JJ66
UniProt Secondary Accession #
Q3TGP1; Q8BPG4; Q99LK3
UniProt Related Accession #
Q9JJ66
GenBank Nucleotide #
NM_023223.2
NCBI Official Full Name
cell division cycle protein 20 homolog
NCBI Official Synonym Full Names
cell division cycle 20
NCBI Official Symbol
Cdc20
NCBI Official Synonym Symbols
C87100; p55CDC; 2310042N09Rik
UniProt Protein Name
Cell division cycle protein 20 homolog
UniProt Synonym Protein Names
p55CDC
Protein Family
Anaphase-promoting complex
UniProt Gene Name
Cdc20
UniProt Synonym Gene Names
mmCdc20
NCBI Protein Information
cell division cycle protein 20 homolog

UniProt Comments for Cdc20

Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentiation.
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Research Articles on Cdc20

1. Cdc20 hypomorphism causes chromatin bridging and chromosome misalignment, revealing a requirement for Cdc20 in efficient sister chromosome separation and chromosome-microtubule attachment.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Cdc20 recombinant protein

 Products by Pathway  Pathway Diagram
 APC/C Complex Pathway antibodies  APC/C Complex Pathway Diagram
 APC/C Complex Pathway antibodies  APC/C Complex Pathway Diagram
 APC/C-mediated Degradation Of Cell Cycle Proteins Pathway antibodies  APC/C-mediated Degradation Of Cell Cycle Proteins Pathway Diagram
 APC/C:Cdc20 Mediated Degradation Of Cyclin B Pathway antibodies  APC/C:Cdc20 Mediated Degradation Of Cyclin B Pathway Diagram
 APC/C:Cdc20 Mediated Degradation Of Securin Pathway antibodies  APC/C:Cdc20 Mediated Degradation Of Securin Pathway Diagram
 APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway antibodies  APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway Diagram
 APC/C:Cdh1 Mediated Degradation Of Cdc20 And Other APC/C:Cdh1 Targeted Proteins In Late Mitosis/early G1 Pathway antibodies  APC/C:Cdh1 Mediated Degradation Of Cdc20 And Other APC/C:Cdh1 Targeted Proteins In Late Mitosis/early G1 Pathway Diagram
 Activation Of APC/C And APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway antibodies  Activation Of APC/C And APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Checkpoints Pathway antibodies  Cell Cycle Checkpoints Pathway Diagram

Diseases associated with Cdc20 recombinant protein

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >78 publications with Cdc20 and Neoplasms
 Carcinoma Antibodies  >23 publications with Cdc20 and Carcinoma
 Cell Transformation, Neoplastic Antibodies  >14 publications with Cdc20 and Cell Transformation, Neoplastic
 Breast Neoplasms Antibodies  >12 publications with Cdc20 and Breast Neoplasms
 Adenocarcinoma Antibodies  >10 publications with Cdc20 and Adenocarcinoma
 Lung Neoplasms Antibodies  >9 publications with Cdc20 and Lung Neoplasms
 Neoplasms, Experimental Antibodies  >8 publications with Cdc20 and Neoplasms, Experimental
 Lung Diseases Antibodies  >8 publications with Cdc20 and Lung Diseases
 Disease Models, Animal Antibodies  >6 publications with Cdc20 and Disease Models, Animal
 Drug Toxicity Antibodies  >6 publications with Cdc20 and Drug Toxicity

Organs/Tissues associated with Cdc20 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >17 publications with Cdc20 and Brain
 Lung Antibodies  >14 publications with Cdc20 and Lung
 Liver Antibodies  >11 publications with Cdc20 and Liver
 Prostate Antibodies  >8 publications with Cdc20 and Prostate
 Bone Antibodies  >5 publications with Cdc20 and Bone
 Muscle Antibodies  >4 publications with Cdc20 and Muscle
 Kidney Antibodies  >4 publications with Cdc20 and Kidney
 Bone Marrow Antibodies  >4 publications with Cdc20 and Bone Marrow
 Embryonic Tissue Antibodies  >4 publications with Cdc20 and Embryonic Tissue
 Testis Antibodies  >3 publications with Cdc20 and Testis
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