Human BCAT2 Recombinant Protein – Cat# MBS144504

Branched Chain Amino-Acid Transaminase 2 (BCAT2) Human Recombinant Protein

Name: BCAT2 Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS144504
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS144504

Description: BCAT2 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 390 amino acids (28-392) and having a molecular mass of 43.9kDa.BCAT2 is fused to a 25 amino acid His-tag at N-terminus & purified by… More details

$250 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Branched Chain Amino-Acid Transaminase 2 (BCAT2), Recombinant Protein

Full Product Name

Recombinant Human Branched Chain Amino-Acid Transaminase 2

Product Gene Name

BCAT2 recombinant protein

Product Synonym Names

BCAT2 Human; Branched Chain Amino-Acid Transaminase 2 Human Recombinant; Branched-chain-amino-acid aminotransferase mitochondrial; BCAT(m); Placental protein 18; PP18; BCAT2; BCATM; BCT2; ECA40; BCAM

Sequence

MGSSHHH HHH SSGLVPRGSH MGSHMA SSSF KAADLQLEMT QKPHKKPGPG EPLVFGKTFT DHMLMVEWND KGWGQPRIQP FQNLTLHPAS SSLHYSLQLF EGMKAFKGKD QQVRLFRPWL NMDRMLRSAM RLCLPSFDKL ELLECIRRLI EVDKDWVPDA AGTSLYVRPV LIGNEPSLGV SQPTRALLFV ILCPVGAYFP GGSVTPVSLL ADPAFIRAWV GGVGNYKLGG NYGPTVLVQQ EALKRGCEQV LWLYGPDHQL TEVGTMNIFV YWTHEDGVLE LVTPPLNGVI LPGVVRQSLL DMAQTWGEFR VVERTITMKQ LLRALEEGRV REVFGSGTAC QVCPVHRILY KDRNLHIPTM ENGPELILRF QKELKEIQYG IRAHEWMFPV .

Host

E Coli

Form/Format

The BCAT2 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 7.5), 10% glycerol, 0.2M NaCl and 1mM DTT.
Sterile Filtered colorless solution.

Purity/Purification

Greater than 90.0% as determined by SDS-PAGE.

Molecular Weight

33,777 Da

OMIM

113530

3D Structure

ModBase 3D Structure for O15382

Product Categories/Family for BCAT2 recombinant protein

Enzymes; Transaminase

Other Notes

Small volumes of BCAT2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BCAT2 purchase

MBS144504 is a recombinant protein targeting BCAT2. Also known as Recombinant Human Branched Chain Amino-Acid Transaminase 2. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for BCAT2. It may not necessarily be applicable to this product.

NCBI GI #

258614015

NCBI GeneID

587

NCBI Accession #

NP_001158245.1

UniProt Primary Accession #

O15382

UniProt Secondary Accession #

O00269; Q96KG1; Q9BTB6; Q9BUU6; B2RB87

UniProt Related Accession #

O15382

GenBank Nucleotide #

NM_001164773.1

NCBI Official Full Name

branched-chain-amino-acid aminotransferase, mitochondrial isoform b

NCBI Official Synonym Full Names

branched chain amino-acid transaminase 2, mitochondrial

NCBI Official Symbol

BCAT2

NCBI Official Synonym Symbols

BCAM; BCT2; PP18; BCATM

UniProt Protein Name

Branched-chain-amino-acid aminotransferase, mitochondrial

UniProt Synonym Protein Names

Placental protein 18; PP18

UniProt Gene Name

BCAT2

UniProt Synonym Gene Names

BCATM; BCT2; ECA40; BCAT(m); PP18

UniProt Entry Name

BCAT2_HUMAN

NCBI Protein Information

branched-chain-amino-acid aminotransferase, mitochondrial; branched chain aminotransferase 2, mitochondrial; placental protein 18

NCBI Summary for BCAT2

This gene encodes a branched chain aminotransferase found in mitochondria. The encoded protein forms a dimer that catalyzes the first step in the production of the branched chain amino acids leucine, isoleucine, and valine. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

UniProt Comments for BCAT2

BCAT2: Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. May also function as a transporter of branched chain alpha-keto acids. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. Homodimer. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Mitochondrial; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Transferase; Amino Acid Metabolism - valine, leucine and isoleucine biosynthesis; EC 2.6.1.42; Cofactor and Vitamin Metabolism - pantothenate and CoA biosynthesis

Chromosomal Location of Human Ortholog: 19q13

Cellular Component: mitochondrion; mitochondrial matrix

Molecular Function: branched-chain-amino-acid transaminase activity

Biological Process: valine metabolic process; branched chain family amino acid catabolic process; leucine metabolic process; isoleucine catabolic process; branched chain family amino acid biosynthetic process

Research Articles on BCAT2

1. The mitochondrial isoform human brain BCAT 2 is largely confined to vascular endothelial cells, whereas the cytosolic human brain BCAT 1 is restricted to neurons.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with BCAT2 recombinant protein

Reference Product	PubMed Publications
BCKDHA recombinant protein	>1 publications with BCAT2 and BCKDHA

Pathways associated with BCAT2 recombinant protein

Products by Pathway	Pathway Diagram
2-Oxocarboxylic Acid Metabolism Pathway antibodies	2-Oxocarboxylic Acid Metabolism Pathway Diagram
2-Oxocarboxylic Acid Metabolism Pathway antibodies	2-Oxocarboxylic Acid Metabolism Pathway Diagram
Biosynthesis Of Amino Acids Pathway antibodies	Biosynthesis Of Amino Acids Pathway Diagram
Biosynthesis Of Amino Acids Pathway antibodies	Biosynthesis Of Amino Acids Pathway Diagram
Branched-chain Amino Acid Catabolism Pathway antibodies	Branched-chain Amino Acid Catabolism Pathway Diagram
Leucine Degradation, Leucine => Acetoacetate + Acetyl-CoA Pathway antibodies	Leucine Degradation, Leucine => Acetoacetate + Acetyl-CoA Pathway Diagram
Leucine Degradation, Leucine => Acetoacetate + Acetyl-CoA Pathway antibodies	Leucine Degradation, Leucine => Acetoacetate + Acetyl-CoA Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Amino Acids And Derivatives Pathway antibodies	Metabolism Of Amino Acids And Derivatives Pathway Diagram

Diseases associated with BCAT2 recombinant protein

Disease Name	Pubmed Publications
Maple Syrup Urine Disease Antibodies	>2 publications with BCAT2 and Maple Syrup Urine Disease
Atrophy Antibodies	>1 publications with BCAT2 and Atrophy
Inflammation Antibodies	>1 publications with BCAT2 and Inflammation
Weight Gain Antibodies	>1 publications with BCAT2 and Weight Gain
Adenocarcinoma Antibodies	>1 publications with BCAT2 and Adenocarcinoma
Weight Loss Antibodies	>1 publications with BCAT2 and Weight Loss

Organs/Tissues associated with BCAT2 recombinant protein

Organ/Tissue Name	Pubmed Publications
Adipose Tissue Antibodies	>4 publications with BCAT2 and Adipose Tissue
Muscle Antibodies	>4 publications with BCAT2 and Muscle
Brain Antibodies	>4 publications with BCAT2 and Brain
Blood Antibodies	>3 publications with BCAT2 and Blood
Liver Antibodies	>2 publications with BCAT2 and Liver
Connective Tissue Antibodies	>2 publications with BCAT2 and Connective Tissue
Heart Antibodies	>1 publications with BCAT2 and Heart
Embryonic Tissue Antibodies	>1 publications with BCAT2 and Embryonic Tissue
Placenta Antibodies	>1 publications with BCAT2 and Placenta