Human VTI1B Recombinant Protein – Cat# MBS144506

Vesicle Transport Through Interaction with T-Snares Homolog 1b (VTI1B) Human Recombinant Protein

Name: VTI1B Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS144506
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS144506

Description: VTI1B Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 231 amino acids (1-208 a.a) and having a molecular mass of 26.3kDa (Molecular weight on SDS-PAGE will appear higher).VTI1B is fused to a 23… More details

$250 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Vesicle Transport Through Interaction with t-SNAREs Homolog 1B (VTI1B), Recombinant Protein

Full Product Name

Recombinant Human Vesicle Transport Through Interaction with t-SNAREs Homolog 1B

Product Gene Name

VTI1B recombinant protein

Product Synonym Names

VTI1B Human; Vesicle Transport Through Interaction with t-SNAREs Homolog 1B Human Recombinant; Vesicle transport through interaction with t-SNAREs homolog 1B; Vesicle transport v-SNARE protein Vti1-like 1; Vti1-rp1; VTI1B; VTI1; VTI1L; VTI1L1; VTI2; v-SNARE; VTI1-LIKE

Sequence

MGSSHHH HHH SSGLVPRGSH MGSMAS SAAS SEHFEKLHEI FRGLHEDLQG VPERLLGTAG TEEKKKLIRD FDEKQQEANE TLAEMEEELR YAPLSFRNPM MSKLRNYRKD LAKLHREVRS TPLTATPGGR GDMKYGIYAV ENEHMNRLQS QRAMLLQGTE SLNRATQSIE RSHRIATETD QIGSEIIEEL GEQRDQLERT KSRLVNTSEN LSKSRKILRS MSRKVTTNKL L.

Host

E Coli

Form/Format

VTI1B protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 30% glycerol, 0.15M NaCl and 1mM DTT.
Sterile Filtered colorless solution.

Purity/Purification

Greater than 85.0% as determined by SDS-PAGE.

Preparation and Storage

Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

Molecular Weight

19,810 Da

OMIM

603207

3D Structure

ModBase 3D Structure for Q9UEU0

Product Categories/Family for VTI1B recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins

Other Notes

Small volumes of VTI1B recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for VTI1B purchase

MBS144506 is a recombinant protein targeting VTI1B. Also known as Recombinant Human Vesicle Transport Through Interaction with t-SNAREs Homolog 1B. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for VTI1B. It may not necessarily be applicable to this product.

NCBI GI #

5454166

NCBI GeneID

10490

NCBI Accession #

NP_006361.1

UniProt Primary Accession #

Q9UEU0

UniProt Secondary Accession #

O43547; Q96J28

UniProt Related Accession #

Q9UEU0

GenBank Nucleotide #

NM_006370.2

NCBI Official Full Name

vesicle transport through interaction with t-SNAREs homolog 1B

NCBI Official Synonym Full Names

vesicle transport through interaction with t-SNAREs 1B

NCBI Official Symbol

VTI1B

NCBI Official Synonym Symbols

VTI1; VTI2; VTI1L; v-SNARE; vti1-rp1; VTI1-LIKE

UniProt Protein Name

Vesicle transport through interaction with t-SNAREs homolog 1B

UniProt Synonym Protein Names

Vesicle transport v-SNARE protein Vti1-like 1; Vti1-rp1

Protein Family

Vesicle transport through interaction with t-SNAREs

UniProt Gene Name

VTI1B

UniProt Synonym Gene Names

VTI1; VTI1L; VTI1L1; VTI2

UniProt Entry Name

VTI1B_HUMAN

NCBI Protein Information

vesicle transport through interaction with t-SNAREs homolog 1B; vesicle transport v-SNARE protein Vti1-like 1; vesicle-associated soluble NSF attachment protein receptor

UniProt Comments for VTI1B

VTI1B: V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence. Belongs to the VTI1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Vesicle

Chromosomal Location of Human Ortholog: 14q24.1

Cellular Component: Golgi apparatus; endoplasmic reticulum membrane; intracellular membrane-bound organelle; late endosome membrane; lysosomal membrane; integral to membrane; SNARE complex; recycling endosome; synaptic vesicle; cell soma; perinuclear region of cytoplasm; cytoplasm; vesicle

Molecular Function: SNAP receptor activity; SNARE binding; chloride channel inhibitor activity

Biological Process: vesicle-mediated transport; cell proliferation; intra-Golgi vesicle-mediated transport; ER to Golgi vesicle-mediated transport; autophagic vacuole fusion; Golgi to vacuole transport; protein targeting to vacuole; vesicle fusion with Golgi apparatus; retrograde transport, endosome to Golgi; vesicle docking during exocytosis

Research Articles on VTI1B

1. Vti1b-dependent tethering of Lytic granule and CD3-endo determines accumulation, docking, and efficient lytic granule secretion at the immunological synapse.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with VTI1B recombinant protein

Reference Product	PubMed Publications
STX8 recombinant protein	>4 publications with VTI1B and STX8
STX7 recombinant protein	>4 publications with VTI1B and STX7
STX6 recombinant protein	>3 publications with VTI1B and STX6
CLINT1 recombinant protein	>3 publications with VTI1B and CLINT1
STX16 recombinant protein	>1 publications with VTI1B and STX16
VAMP4 recombinant protein	>1 publications with VTI1B and VAMP4

Pathways associated with VTI1B recombinant protein

Products by Pathway	Pathway Diagram
SNARE Interactions In Vesicular Transport Pathway antibodies	SNARE Interactions In Vesicular Transport Pathway Diagram
SNARE Interactions In Vesicular Transport Pathway antibodies	SNARE Interactions In Vesicular Transport Pathway Diagram

Diseases associated with VTI1B recombinant protein

Disease Name	Pubmed Publications
Disease Models, Animal Antibodies	>2 publications with VTI1B and Disease Models, Animal
Necrosis Antibodies	>2 publications with VTI1B and Necrosis
Edema Antibodies	>1 publications with VTI1B and Edema
Breast Neoplasms Antibodies	>1 publications with VTI1B and Breast Neoplasms
Inflammation Antibodies	>1 publications with VTI1B and Inflammation

Organs/Tissues associated with VTI1B recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>5 publications with VTI1B and Blood
Nerve Antibodies	>3 publications with VTI1B and Nerve
Bone Antibodies	>2 publications with VTI1B and Bone
Liver Antibodies	>2 publications with VTI1B and Liver
Bone Marrow Antibodies	>2 publications with VTI1B and Bone Marrow
Lung Antibodies	>2 publications with VTI1B and Lung
Brain Antibodies	>2 publications with VTI1B and Brain
Ganglia Antibodies	>1 publications with VTI1B and Ganglia
Salivary Gland Antibodies	>1 publications with VTI1B and Salivary Gland
Mouth Antibodies	>1 publications with VTI1B and Mouth