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Regulator of G-Protein Signaling 21 (RGS21) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS144508

Description: RGS21 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 176 amino acids (1-152 a.a.) and having a molecular mass of 20.2kDa.RGS21 is fused to a 24 amino acid His-tag at N-terminus & purified by… More details

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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Regulator of G-Protein Signaling 21 (RGS21), Recombinant Protein
Full Product Name
Recombinant Human Regulator of G-Protein Signaling 21
Product Gene Name
Product Synonym Names
RGS21 Human; Regulator of G-Protein Signaling 21 Human Recombinant; Regulator of G-protein signaling 21; RGS21
Sequence
MGSSHHH HHH SSGLVPRGSH MGSHMP VKCC FYRSPTAETM TWSENMDTLL ANQAGLDAFR IFLKSEFSEE NVEFWLACED FKKTKNADKI ASKAKMIYSE FIEADAPKEI NIDFGTRDLI SKNIAEPTLK CFDEAQKLIY CLMAKDSFPR FLKSEIYKKL VNSQQVPNHK KWLPFL.
Host
E Coli
Form/Format
RGS21 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 30% glycerol and 0.1M NaCl.
Sterile Filtered colorless solution.
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Molecular Weight
17,671 Da
OMIM
612407
3D Structure
ModBase 3D Structure for Q2M5E4

Other Notes

Small volumes of RGS21 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RGS21 purchase

MBS144508 is a recombinant protein targeting RGS21. Also known as Recombinant Human Regulator of G-Protein Signaling 21. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for RGS21. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
regulator of G-protein signaling 21
NCBI Official Synonym Full Names
regulator of G-protein signaling 21
NCBI Official Symbol
RGS21
UniProt Protein Name
Regulator of G-protein signaling 21
UniProt Gene Name
RGS21
UniProt Synonym Gene Names
RGS21
UniProt Entry Name
RGS21_HUMAN
NCBI Protein Information
regulator of G-protein signaling 21; regulator of G-protein signalling 21

NCBI Summary for RGS21

Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins are GTPase-activating proteins for Gi (see GNAI1; MIM 139310) and Gq (see GNAQ; MIM 600998) class G-alpha proteins. They accelerate transit through the cycle of GTP binding and hydrolysis and thereby accelerate signaling kinetics and termination.[supplied by OMIM, Nov 2008]
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UniProt Comments for RGS21

RGS21: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.

Protein type: GAPs, misc.; GAPs

Chromosomal Location of Human Ortholog: 1q31.2

Cellular Component: cytoplasm; plasma membrane

Molecular Function: GTPase activator activity

Biological Process: positive regulation of GTPase activity
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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