Human RND1 Recombinant Protein – Cat# MBS144668

Rho Family Gtpase 1 (RND1) Human Recombinant Protein

Name: RND1 Recombinant Protein; Rho Family Gtpase 1; Human; MyBioSource
Brand: MyBioSource
SKU: MBS144668
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS144668

Description: RND1 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 220 amino acids (1-200) and having a molecular mass of 24.5 kDa.The RND1 is fused to a 20 amino acid His-Tag at N-terminus and purified by… More details

$250 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Rho Family GTPase 1 (RND1), Recombinant Protein

Full Product Name

Recombinant Human Rho Family GTPase 1

Product Gene Name

RND1 recombinant protein

Product Synonym Names

RND1 Human; Rho Family GTPase 1 Human Recombinant

Sequence

MGSSHHH HHH SSGLVPRGSH MKERRAPQPV VARCKLVLVG DVQCGKTAML QVLAKDCYPE TYVPTVFENY TACLETEEQR VELSLWDTSG SPYYDNVRPL CYSDSDAVLL CFDISRPETV DSALKKWRTE ILDYCPSTRV LLIGCKTDLR TDLSTLMELS HQKQAPISYE QGCAIAKQLG AEIYLEGSAF TSEKSIHSIF RTASMLCLNK PSPLPQKSPV

Host

E Coli

Form/Format

The RND1 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 0.1M NaCl and 30% glycerol.
Sterile Filtered colorless solution.

Purity/Purification

Greater than 95% as determined by SDS-PAGE.

Molecular Weight

26,056 Da

OMIM

609038

3D Structure

ModBase 3D Structure for Q92730

Product Categories/Family for RND1 recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins; Rho Family GTPase

Other Notes

Small volumes of RND1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RND1 purchase

MBS144668 is a recombinant protein targeting RND1. Also known as Recombinant Human Rho Family GTPase 1. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for RND1. It may not necessarily be applicable to this product.

NCBI GI #

7657514

NCBI GeneID

27289

NCBI Accession #

NP_055285.1

UniProt Primary Accession #

Q92730

UniProt Secondary Accession #

A8K9P7

UniProt Related Accession #

Q92730

GenBank Nucleotide #

NM_014470.3

NCBI Official Full Name

rho-related GTP-binding protein Rho6

NCBI Official Synonym Full Names

Rho family GTPase 1

NCBI Official Symbol

RND1

NCBI Official Synonym Symbols

ARHS; RHO6; RHOS

UniProt Protein Name

Rho-related GTP-binding protein Rho6

UniProt Synonym Protein Names

Rho family GTPase 1; Rnd1

Protein Family

Rho-related GTP-binding protein

UniProt Gene Name

RND1

UniProt Synonym Gene Names

RHO6

UniProt Entry Name

RND1_HUMAN

NCBI Protein Information

rho-related GTP-binding protein Rho6; ras homolog gene family, member S

NCBI Summary for RND1

This gene encodes a protein that belongs to the Rho GTPase family. Members of this family regulate the organization of the actin cytoskeleton in response to extracellular growth factors. A similar protein in rat interacts with a microtubule regulator to control axon extension. [provided by RefSeq, Apr 2014]

UniProt Comments for RND1

RND1: Lacks intrinsic GTPase activity. Has a low affinity for GDP, and constitutively binds GTP. Controls rearrangements of the actin cytoskeleton. Induces the Rac-dependent neuritic process formation in part by disruption of the cortical actin filaments. Causes the formation of many neuritic processes from the cell body with disruption of the cortical actin filaments. Belongs to the small GTPase superfamily. Rho family.

Protein type: G protein, monomeric, Rho; G protein, monomeric; G protein

Chromosomal Location of Human Ortholog: 12q12

Cellular Component: cytoskeleton; adherens junction; plasma membrane; cytosol

Molecular Function: GTPase activity; protein binding; GTP binding; receptor binding

Biological Process: axon guidance; metabolic process; small GTPase mediated signal transduction; actin filament organization; negative regulation of cell adhesion; neuron remodeling

Research Articles on RND1

1. Data indicate that Rnd1 efficiently displaces Rac1 from its complex with Plexin-B1 but not vice versa.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with RND1 recombinant protein

Reference Product	PubMed Publications
PLXNB1 recombinant protein	>6 publications with RND1 and PLXNB1
SEMA4D recombinant protein	>4 publications with RND1 and SEMA4D
SEMA3A recombinant protein	>3 publications with RND1 and SEMA3A
PLXNA1 recombinant protein	>2 publications with RND1 and PLXNA1
ROCK2 recombinant protein	>1 publications with RND1 and ROCK2
GRLF1 recombinant protein	>1 publications with RND1 and GRLF1
FRS2 recombinant protein	>1 publications with RND1 and FRS2
GRB7 recombinant protein	>1 publications with RND1 and GRB7

Pathways associated with RND1 recombinant protein

Products by Pathway	Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Developmental Biology Pathway antibodies	Developmental Biology Pathway Diagram
SEMA3A-Plexin Repulsion Signaling By Inhibiting Integrin Adhesion Pathway antibodies	SEMA3A-Plexin Repulsion Signaling By Inhibiting Integrin Adhesion Pathway Diagram
Sema4D In Semaphorin Signaling Pathway antibodies	Sema4D In Semaphorin Signaling Pathway Diagram
Sema4D Induced Cell Migration And Growth-cone Collapse Pathway antibodies	Sema4D Induced Cell Migration And Growth-cone Collapse Pathway Diagram
Sema4D Mediated Inhibition Of Cell Attachment And Migration Pathway antibodies	Sema4D Mediated Inhibition Of Cell Attachment And Migration Pathway Diagram
Semaphorin Interactions Pathway antibodies	Semaphorin Interactions Pathway Diagram

Diseases associated with RND1 recombinant protein

Disease Name	Pubmed Publications
Necrosis Antibodies	>5 publications with RND1 and Necrosis
Nervous System Diseases Antibodies	>3 publications with RND1 and Nervous System Diseases
Inflammation Antibodies	>3 publications with RND1 and Inflammation
Pain Antibodies	>1 publications with RND1 and Pain
Abnormalities, Multiple Antibodies	>1 publications with RND1 and Abnormalities, Multiple
Disease Models, Animal Antibodies	>1 publications with RND1 and Disease Models, Animal
Drug-Related Side Effects and Adverse Reactions Antibodies	>1 publications with RND1 and Drug-Related Side Effects and Adverse Reactions
Neoplasms, Experimental Antibodies	>1 publications with RND1 and Neoplasms, Experimental
Heart Diseases Antibodies	>1 publications with RND1 and Heart Diseases
Kidney Diseases Antibodies	>1 publications with RND1 and Kidney Diseases

Organs/Tissues associated with RND1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>14 publications with RND1 and Brain
Embryonic Tissue Antibodies	>4 publications with RND1 and Embryonic Tissue
Bone Antibodies	>3 publications with RND1 and Bone
Testis Antibodies	>2 publications with RND1 and Testis
Lung Antibodies	>2 publications with RND1 and Lung
Heart Antibodies	>1 publications with RND1 and Heart
Liver Antibodies	>1 publications with RND1 and Liver