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Parathyroid Hormone (PTHrP) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS144678

Description: PTHrP N15 Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 86 amino acids, having an MW of 10033 Da labeled by the stable isotope N15.The PTHrP is purified by proprietary chromatographic… More details

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Product Overview

Online Datasheet in PDF
Product Name
Parathyroid Hormone (PTHrP), Recombinant Protein
Full Product Name
Recombinant Human Parathyroid Hormone Related Protein N15 Labeled
Product Gene Name
Product Synonym Names
PTHrP N15 Human; Parathyroid Hormone Related Protein N15 Labeled Human Recombinant; Parathyroid Hormone 2; PTH2; TIPF39; Tuberoinfundibular 39 Residue Protein; PTHrP N15
Sequence
AVSEHQLLHD KGKSIQDLRR RFFLHHLIAE IHTAEIRATS EVSPNSKPSP NTKNHPVRFG SDDEGRYLTQ ETNKVETYKE QPLKTP
Host
E Coli
Form/Format
PthRp N15 protein was lyophilized from a 0.2 um filtered concentrated solution in 1xPBS, pH 7.4.
Sterile Filtered White lyophilized (freeze-dried) powder.
Purity/Purification
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Molecular Weight
11,202 Da
OMIM
608386
3D Structure
ModBase 3D Structure for Q96A98
Solubility
It is recommended to be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in 10mM HAc to a concentration of 0.1-1.0 mg/mL. Further dilutions should be made in appropriate buffered solutions.

Product Categories/Family for PTHrP recombinant protein

Other Notes

Small volumes of PTHrP recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PTHrP purchase

MBS144678 is a recombinant protein targeting PTHrP. Also known as Recombinant Human Parathyroid Hormone Related Protein N15 Labeled. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for PTHrP. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
tuberoinfundibular peptide of 39 residues preproprotein
NCBI Official Synonym Full Names
parathyroid hormone 2
NCBI Official Symbol
PTH2
NCBI Official Synonym Symbols
TIP39
UniProt Protein Name
Tuberoinfundibular peptide of 39 residues
UniProt Synonym Protein Names
Parathyroid hormone 2
Protein Family
UniProt Gene Name
PTH2
UniProt Synonym Gene Names
TIP39; TIPF39; TIP39
UniProt Entry Name
TIP39_HUMAN
NCBI Protein Information
tuberoinfundibular peptide of 39 residues; tuberoinfundibular 39 residue protein; tuberoinfundibular 39 residues

NCBI Summary for PTHrP

TIP39 is related to parathyroid hormone (PTH; MIM 168450) and PTH-related protein (PTHRP; MIM 168470) and is a ligand for PTH receptor-2 (PTHR2; MIM 601469) (John et al., 2002 [PubMed 11861531]).[supplied by OMIM, Mar 2008]

UniProt Comments for PTHrP

PTH2: Plays a role as a potent and selective agonist of PTH2R resulting in adenyl cyclase activation and intracellular calcium levels elevation. Induces protein kinase C beta activation, recruitment of beta-arrestin and PTH2R internalization. May inhibit cell proliferation via its action on PTH2R activation. Neuropeptide which may also have a role in spermatogenesis. May activate nociceptors and nociceptive circuits. Belongs to the parathyroid hormone family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 19q13.33

Cellular Component: extracellular region

Biological Process: neuropeptide signaling pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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