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LSM2 Homolog (LSM2) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS144726

Description: LSM2 Human Recombinant produced in E Coli is a single polypeptide chain containing 119 amino acids (1-95) and having a molecular mass of 13.4kDa.LSM2 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic… More details

$250 / 0.005 mg +1 FREE 8GB USB
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
LSM2 Homolog, Recombinant Protein
Full Product Name
Recombinant Human LSM2 Homolog, U6 Small Nuclear RNA Associated
Product Gene Name
Product Synonym Names
LSM2 Human; LSM2 Homolog, U6 Small Nuclear RNA Associated Human Recombinant; LSM2 homolog U6 small nuclear RNA associated (S. cerevisiae); Small nuclear ribonuclear protein D homolog; chromosome 6 open reading frame 28; snRNP core Sm-like protein Sm-x5; C6orf28; YBL026W; Protein G7b; snRNP
Sequence
MGSSHHH HHH SSGLVPRGSH MGSHML FYSF FKSLVGKDVV VELKNDLSIC GTLHSVDQYL NIKLTDISVT DPEKYPHMLS VKNCFIRGSV VRYVQLPADE VDTQLLQDAA RKEALQQKQ
Host
E Coli
Form/Format
The LSM2 solution (0.5mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 200mM Nacl, 5mM DTT and 40% glycerol.
Sterile Filtered colorless solution.
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Molecular Weight
10,835 Da
OMIM
607282
3D Structure
ModBase 3D Structure for Q9Y333

Other Notes

Small volumes of LSM2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LSM2 purchase

MBS144726 is a recombinant protein targeting LSM2. Also known as Recombinant Human LSM2 Homolog, U6 Small Nuclear RNA Associated. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for LSM2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
U6 snRNA-associated Sm-like protein LSm2
NCBI Official Synonym Full Names
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
NCBI Official Symbol
LSM2
NCBI Official Synonym Symbols
G7B; snRNP; C6orf28; YBL026W
UniProt Protein Name
U6 snRNA-associated Sm-like protein LSm2
UniProt Synonym Protein Names
Protein G7b; Small nuclear ribonuclear protein D homolog; snRNP core Sm-like protein Sm-x5
UniProt Gene Name
LSM2
UniProt Synonym Gene Names
C6orf28; G7B
UniProt Entry Name
LSM2_HUMAN
NCBI Protein Information
U6 snRNA-associated Sm-like protein LSm2; protein G7b; small nuclear ribonuclear protein D homolog; snRNP core Sm-like protein Sm-x5

NCBI Summary for LSM2

This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 19. [provided by RefSeq, Nov 2011]
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UniProt Comments for LSM2

LSM2: Binds specifically to the 3'-terminal U-tract of U6 snRNA. May be involved in pre-mRNA splicing. Identified in the spliceosome C complex. LSm subunits form a heteromer with a doughnut shape. Belongs to the snRNP Sm proteins family.

Protein type: RNA-binding; RNA splicing; Spliceosome

Chromosomal Location of Human Ortholog: 6p21.3

Cellular Component: nucleoplasm; cytosol

Molecular Function: protein binding; Ral GTPase binding; protein kinase binding; U6 snRNA binding

Biological Process: nuclear mRNA splicing, via spliceosome; RNA splicing; gene expression; mRNA catabolic process, deadenylation-dependent decay
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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