Human MUTED Recombinant Protein – Cat# MBS144851

MUTED Human Recombinant Protein

Name: MUTED Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS144851
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS144851

Description: BLOC1S5 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 210 amino acids (1-187 a.a) and having a molecular mass of 24kDa.BLOC1S5 is fused to a 23 amino acid His-tag at N-terminus & purified by… More details

$250 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

MUTED, Recombinant Protein

Full Product Name

Recombinant Human MUTED

Product Gene Name

MUTED recombinant protein

Product Synonym Names

BLOC1S5 Human; Biogenesis of Lysosomal Organelles Complex-1, Subunit 5 Human Recombinant; Biogenesis of lysosome-related organelles complex 1 subunit 5; BLOC-1 subunit 5; Protein Muted homolog; BLOC1S5; MUTED

Sequence

MGSSHHH HHH SSGLVPRGSH MGSMSG GGTE TPVGCEAAPG GGSKKRDSLG TAGSAHLIIK DLGEIHSRLL DHRPVIQGET RYFVKEFEEK RGLREMRVLE NLKNMIHETN EHTLPKCRDT MRDSLSQVLQ RLQAANDSVC RLQQREQERK KIHSDHLVAS EKQHMLQWDN FMKEQPNKRA EVDEEHRKAM ERLKEQYAEM EKDLAKFSTF .

Host

E Coli

Form/Format

BLOC1S5 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl, 40% glycerol, 2mM DTT, 0.1mM PMSF and 1mM EDTA.
Sterile Filtered colorless solution.

Purity/Purification

Greater than 90.0% as determined by SDS-PAGE.

Preparation and Storage

Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

Molecular Weight

14,893 Da

OMIM

607289

3D Structure

ModBase 3D Structure for Q8TDH9

Product Categories/Family for MUTED recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins

Other Notes

Small volumes of MUTED recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MUTED purchase

MBS144851 is a recombinant protein targeting MUTED. Also known as Recombinant Human MUTED. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for MUTED. It may not necessarily be applicable to this product.

NCBI GI #

313482848

NCBI GeneID

63915

NCBI Accession #

NP_001186251.1

UniProt Primary Accession #

Q8TDH9

UniProt Secondary Accession #

Q0VDJ6; Q0VDJ7; Q5THS1; Q68D56; Q8N5F9; Q9NU16; B4DVM2

UniProt Related Accession #

Q8TDH9

GenBank Nucleotide #

NM_001199322.1

NCBI Official Full Name

biogenesis of lysosome-related organelles complex 1 subunit 5 isoform 2

NCBI Official Synonym Full Names

biogenesis of lysosomal organelles complex-1, subunit 5, muted

NCBI Official Symbol

BLOC1S5

NCBI Official Synonym Symbols

MU; BLOS5; MUTED

UniProt Protein Name

Biogenesis of lysosome-related organelles complex 1 subunit 5

UniProt Synonym Protein Names

Protein Muted homolog

Protein Family

Biogenesis of lysosome-related organelles complex

UniProt Gene Name

BLOC1S5

UniProt Synonym Gene Names

MUTED; BLOC-1 subunit 5

UniProt Entry Name

BL1S5_HUMAN

NCBI Protein Information

biogenesis of lysosome-related organelles complex 1 subunit 5; BLOC-1 subunit 5; muted homolog; protein Muted homolog

NCBI Summary for MUTED

This gene encodes a component of BLOC-1 (biogenesis of lysosome-related organelles complex 1). Components of this complex are involved in the biogenesis of organelles such as melanosomes and platelet-dense granules. A mouse model for Hermansky-Pudlak Syndrome is mutated in the murine version of this gene. Alternative splicing results in multiple transcript variants. Read-through transcription exists between this gene and the upstream EEF1E1 (eukaryotic translation elongation factor 1 epsilon 1) gene, as well as with the downstream TXNDC5 (thioredoxin domain containing 5) gene. [provided by RefSeq, Dec 2010]

UniProt Comments for MUTED

MUTED: The BLOC-1 complex is required for normal biogenesis of lysosome-related organelles, such as platelet dense granules and melanosomes. Plays a role in intracellular vesicle trafficking. Belongs to the Muted family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 6p25.1-p24.3

Cellular Component: transport vesicle

Molecular Function: protein binding

Biological Process: positive regulation of pigment cell differentiation; melanosome organization and biogenesis; otolith morphogenesis; anterograde synaptic vesicle transport; anterograde axon cargo transport; melanosome transport; neurite development

Research Articles on MUTED

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with MUTED recombinant protein

Reference Product	PubMed Publications
DTNBP1 recombinant protein	>1 publications with MUTED and DTNBP1

Organs/Tissues associated with MUTED recombinant protein

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>1 publications with MUTED and Lung
Brain Antibodies	>1 publications with MUTED and Brain