Rat rBD 1 Active Protein – Cat# MBS144913

Beta Defensin -1 (rBD 1) Rat Active Protein

Name: rBD 1 Active Protein; Beta Defensin -1; Rat; MyBioSource
Brand: MyBioSource
SKU: MBS144913
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS144913

Description: BD-1 Rat Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 37 amino acids and having a molecular mass of 4.1kDa.The BD-1 is purified by proprietary chromatographic techniques.Introduction: The Defensin… More details

$250 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Beta Defensin -1 (rBD 1), Active Protein

Full Product Name

Recombinant Rat Beta Defensin -1

Product Gene Name

rBD 1 active protein

Product Synonym Names

BD 1 Rat; Beta Defensin -1 Rat Recombinant; Beta-defensin 1; BD-1; rBD-1; Defensin beta 1; Defb1

Sequence

DQYRCLQNGG FCLRSSCPSH TKLQGTCKPD KPNCCRS

Host

E Coli

Form/Format

BD-1 protein was lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4.
Sterile Filtered White lyophilized (freeze-dried) powder.

Purity/Purification

Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

Preparation and Storage

Lyophilized BD-1 although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution BD-1 should be stored at 4 degree C between 2-7 days and for future use below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Molecular Weight

7,837 Da

3D Structure

ModBase 3D Structure for O89117

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Solubility

It is recommended to reconstitute the lyophilized BD-1 in sterile 18M-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.

Biological Activity

Measured by its ability to chemoattract CD34+ dendritic cells using a concentration range of 0.1-1.0 ug/ml.

Product Categories/Family for rBD 1 active protein

Cytokines and Growth Factors; Cytokines; Beta Defensin

Other Notes

Small volumes of rBD 1 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for rBD 1 purchase

MBS144913 is an active protein targeting rBD 1. Also known as Recombinant Rat Beta Defensin -1. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for rBD 1. It may not necessarily be applicable to this product.

NCBI GI #

13929150

NCBI GeneID

83687

NCBI Accession #

NP_113998.1

UniProt Primary Accession #

O89117

UniProt Related Accession #

O89117

GenBank Nucleotide #

NM_031810.1

NCBI Official Full Name

beta-defensin 1

NCBI Official Synonym Full Names

defensin beta 1

NCBI Official Symbol

Defb1

UniProt Protein Name

Beta-defensin 1

UniProt Synonym Protein Names

Defensin, beta 1

Protein Family

Beta-defensin

UniProt Gene Name

Defb1

UniProt Synonym Gene Names

BD-1; rBD-1

UniProt Entry Name

DEFB1_RAT

NCBI Protein Information

beta-defensin 1; BD-1; rBD-1

NCBI Summary for rBD 1

cationic peptides with broad-spectrum antimicrobial activity; may mediate mucosal defenses of several organs [RGD, Feb 2006]

UniProt Comments for rBD 1

defensin, beta 1: Has bactericidal activity. Belongs to the beta-defensin family.

Protein type: Secreted; Motility/polarity/chemotaxis; Secreted, signal peptide

Cellular Component: extracellular space

Biological Process: defense response to Gram-positive bacterium; response to bacterium; innate immune response in mucosa; antibacterial humoral response; innate immune response; response to testosterone stimulus; acute inflammatory response

Research Articles on rBD 1

1. The -44CC SNP genotype was more common in endophthalmitis, and a mini-haplotype including this single-nucleotide polymorphism was associated strongly with endophthalmitis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with rBD 1 active protein

Reference Product	PubMed Publications
Defb4 active protein	>10 publications with rBD 1 and Defb4
Defa6 active protein	>5 publications with rBD 1 and Defa6
Ccr6 active protein	>4 publications with rBD 1 and Ccr6
Defb3 active protein	>2 publications with rBD 1 and Defb3
Defb14 active protein	>2 publications with rBD 1 and Defb14

Pathways associated with rBD 1 active protein

Products by Pathway	Pathway Diagram
Beta Defensins Pathway antibodies	Beta Defensins Pathway Diagram
Defensins Pathway antibodies	Defensins Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram

Diseases associated with rBD 1 active protein

Disease Name	Pubmed Publications
Inflammation Antibodies	>61 publications with rBD 1 and Inflammation
Necrosis Antibodies	>34 publications with rBD 1 and Necrosis
Lung Diseases Antibodies	>32 publications with rBD 1 and Lung Diseases
Carcinoma Antibodies	>22 publications with rBD 1 and Carcinoma
Fibrosis Antibodies	>18 publications with rBD 1 and Fibrosis
Kidney Diseases Antibodies	>8 publications with rBD 1 and Kidney Diseases
Adenoma Antibodies	>4 publications with rBD 1 and Adenoma
Prostatic Neoplasms Antibodies	>4 publications with rBD 1 and Prostatic Neoplasms
Precancerous Conditions Antibodies	>3 publications with rBD 1 and Precancerous Conditions
Lung Neoplasms Antibodies	>3 publications with rBD 1 and Lung Neoplasms

Organs/Tissues associated with rBD 1 active protein

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>30 publications with rBD 1 and Kidney
Eye Antibodies	>7 publications with rBD 1 and Eye