Human AER61 Recombinant Protein – Cat# MBS1449300

Uncharacterized Glycosyltransferase AER61 (AER61) Human Recombinant Protein

Name: AER61 Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1449300
Price: 1310 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1449300

MBS1449300 is a recombinant protein targeting AER61. Also known as Recombinant Human Uncharacterized glycosyltransferase AER61 (AER61). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1310 / 0.02 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Uncharacterized glycosyltransferase AER61 (AER61), Recombinant Protein

Full Product Name

Recombinant Human Uncharacterized glycosyltransferase AER61 (AER61)

Product Gene Name

AER61 recombinant protein

Product Synonym Gene Name

AER61

Sequence

GQNEAPPNTH SIPGEPLYNY ASIRLPEEHI PFFLHNNRHI ATVCRKDSLC PYKKHLEKLK YCWGYEKSCK PEFRFGYPVC SYVDMGWTDT LESAEDIFWK QADFGYARER LEEMHVLCQP KETSDSSLVC SRYLQYCRAT NLYLDLRNIK RNHDRFKEDF FQSGEIGGHC KLDIRTLTSE GQRKSPLQSW FAELQSYTQL NFRPIEDAKC DIVIEKPTYF MKLDAGVNMY HHFCDFINLY ITQHVNNSFS TDVYIVMWDT SSYGYGDLFS DTWNAFTDYD VIHLKTYDSK RVCFKEAVFS LLPRMRYGLF YNTPLISGCQ NTGLFRAFAQ HVLHRLNITQ EGPKDGKIRV TILARSTEYR KILNQNELVN ALKTVSTFEV QIVDYKYREL GFLDQLRITH NTDIFIGMHG AGLTHLLFLP DWAAVFELYN CEDERCYLDL ARLRGVHYIT WRRQNKVFPQ DKGHHPTLGE HPKFTNYSFD VEEFMYLVLQ AADHVLQHPK WPFKKKHDEL

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

52,297 Da

Sequence Positions

18-527, Full length protein

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

OMIM

614789

3D Structure

ModBase 3D Structure for Q5NDL2

Species

Human

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of AER61 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for AER61. It may not necessarily be applicable to this product.

NCBI GI #

522838254

NCBI GeneID

285203

NCBI Accession #

NP_001265618.1

UniProt Primary Accession #

Q5NDL2

UniProt Secondary Accession #

Q6MZY0; Q6P985; Q6ZTV0; A8K2U1; B4DFH5; L7X1M5

UniProt Related Accession #

Q5NDL2

GenBank Nucleotide #

NM_001278689.1

NCBI Official Full Name

EGF domain-specific O-linked N-acetylglucosamine transferase isoform a

NCBI Official Synonym Full Names

EGF domain specific O-linked N-acetylglucosamine transferase

NCBI Official Symbol

EOGT

NCBI Official Synonym Symbols

AOS4; AER61; EOGT1; C3orf64

UniProt Protein Name

EGF domain-specific O-linked N-acetylglucosamine transferase

UniProt Synonym Protein Names

Extracellular O-linked N-acetylglucosamine transferase

UniProt Gene Name

EOGT

UniProt Synonym Gene Names

AER61; C3orf64; EOGT1

NCBI Protein Information

EGF domain-specific O-linked N-acetylglucosamine transferase

NCBI Summary for AER61

This gene encodes an enzyme that acts in the lumen of the endoplasmic reticulum to catalyze the transfer of N-acetylglucosamine to serine or threonine residues of extracellular-targeted proteins. This enzyme modifies proteins containing eukaryotic growth factor (EGF)-like domains, including the Notch receptor, thereby regulating developmental signalling. Mutations in this gene have been observed in individuals with Adams-Oliver syndrome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]

UniProt Comments for AER61

Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in extracellular proteins resulting in their modification with a beta-linked N-acetylglucosamine (O-GlcNAc). Specifically glycosylates the Thr residue located between the fifth and sixth conserved cysteines of folded EGF-like domains.

Research Articles on AER61

1. Analysis of midluteal endometrial biopsies revealed an inverse correlation between endometrial EOGT and ENHO expression and body mass index. obesity impairs the EOGT-adropin axis in decidual cells, which in turn points toward a mechanistic link between metabolic disorders and adverse pregnancy outcome.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with AER61 recombinant protein

Products by Pathway	Pathway Diagram
Other Types Of O-glycan Biosynthesis Pathway antibodies	Other Types Of O-glycan Biosynthesis Pathway Diagram
Other Types Of O-glycan Biosynthesis Pathway antibodies	Other Types Of O-glycan Biosynthesis Pathway Diagram

Diseases associated with AER61 recombinant protein

Disease Name	Pubmed Publications
Congenital Abnormalities Antibodies	>2 publications with AER61 and Congenital Abnormalities
Nervous System Malformations Antibodies	>1 publications with AER61 and Nervous System Malformations
Musculoskeletal Abnormalities Antibodies	>1 publications with AER61 and Musculoskeletal Abnormalities
Abnormalities, Multiple Antibodies	>1 publications with AER61 and Abnormalities, Multiple
Bone Diseases, Developmental Antibodies	>1 publications with AER61 and Bone Diseases, Developmental

Organs/Tissues associated with AER61 recombinant protein

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>1 publications with AER61 and Bone
Lung Antibodies	>1 publications with AER61 and Lung
Blood Antibodies	>1 publications with AER61 and Blood
Vascular Antibodies	>1 publications with AER61 and Vascular