Xenopus Tropicalis wnt11b-2 Recombinant Protein – Cat# MBS1449369

Protein Wnt-11b-2 (wnt11b-2) Xenopus Tropicalis Recombinant Protein

Name: wnt11b-2 Recombinant Protein; Xenopus Tropicalis; MyBioSource
Brand: MyBioSource
SKU: MBS1449369
Price: 1040 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1449369

MBS1449369 is a recombinant protein targeting wnt11b-2. Also known as Recombinant Xenopus tropicalis Protein Wnt-11b-2 (wnt11b-2). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1040 / 0.02 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Protein Wnt-11b-2 (wnt11b-2), Recombinant Protein

Full Product Name

Recombinant Xenopus tropicalis Protein Wnt-11b-2 (wnt11b-2)

Product Gene Name

wnt11b-2 recombinant protein

Product Synonym Gene Name

wnt11b-2

Sequence

IQWLGLTVNG SRVAWNESEH CRLLDGLVPE QSQLCKRNLE LMQSVVNAAK QAKLTCQMTF SDMRWNCSSV ENAPNFTPDL SKGTRESAFV YALASATISH TIARACASGE LPTCSCGATP AEVPGTGFRW GGCGDNLHYG LNMGSAFVDA PMKSSKSGGT QATKMINLHN NAVGRQVLMD SLETKCKCHG VSGSCSVKTC WKGLQDLPHI ANELKSKYLG ATKVIHRQTG TRRQLVPREL DIRPVRESEL VYLVSSPDYC AKNPKLGSYG TQDRVCNKTS VGSDSCNLMC CGRGYNAYTE TIVERCQCKY YWCCYVMCKK CERTVERYVC K

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

38,858 Da

Sequence Positions

23-353, Full length protein

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for Q28J82

Species

Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of wnt11b-2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for wnt11b-2. It may not necessarily be applicable to this product.

NCBI GI #

62857873

NCBI GeneID

549489

NCBI Accession #

NP_001016735.1

UniProt Primary Accession #

Q28J82

UniProt Related Accession #

Q28J82

GenBank Nucleotide #

NM_001016735.2

NCBI Official Full Name

protein Wnt-11b-2

NCBI Official Synonym Full Names

wingless-type MMTV integration site family, member 11B

NCBI Official Symbol

wnt11b

NCBI Official Synonym Symbols

wnt11; wnt-11; xwnt11; XWnt-11; wnt11b-2

UniProt Protein Name

Protein Wnt-11b-2

Protein Family

Protein

UniProt Gene Name

wnt11b-2

NCBI Protein Information

protein Wnt-11b-2

UniProt Comments for wnt11b-2

Ligand for the frizzled7 transmembrane receptor. Primarily acts via non-canonical Wnt pathways mediated by either Ca2+ and PKC, or by JNK and dvl2/dsh. Depending on the cellular context, can also signal via the canonical Wnt pathway mediated by beta-catenin and dvl2/dsh. May also inhibit canonical Wnt signaling. Maternally initiates dorsal/ventral axis formation by a canonical route, which signals via lrp6. In a complex with wnt5a, activates the canonical and non-canonical processes involved in axis formation. In the non-canonical pathway, acts through fzd7/fz7 to induce phosphorylation of dvl2/dsh. Signals through a non-canonical Wnt pathway to regulate convergent extension movements during gastrulation. Interactions with the secreted Wnt antagonist sfrp5 to coordinate foregut development, acting via a non-canonical wnt pathway whereby sfrp5 restricts wnt11b activity to prevent inappropriate foregut formation. Mediates cardiogenesis via non-canonical Wnt signaling involving JNK-activation and PKC. Acts redundantly with wnt11/wnt11r during pronephros induction ().

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with wnt11b-2 recombinant protein

Products by Pathway	Pathway Diagram
Asymmetric Localization Of PCP Proteins Pathway antibodies	Asymmetric Localization Of PCP Proteins Pathway Diagram
Ca2+ Pathway antibodies	Ca2+ Pathway Diagram
Class B/2 (Secretin Family Receptors) Pathway antibodies	Class B/2 (Secretin Family Receptors) Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
Hedgehog Signaling Pathway antibodies	Hedgehog Signaling Pathway Diagram
Hedgehog Signaling Pathway antibodies	Hedgehog Signaling Pathway Diagram
Melanogenesis Pathway antibodies	Melanogenesis Pathway Diagram
Melanogenesis Pathway antibodies	Melanogenesis Pathway Diagram
PCP/CE Pathway antibodies	PCP/CE Pathway Diagram

Diseases associated with wnt11b-2 recombinant protein

Disease Name	Pubmed Publications
Breast Neoplasms Antibodies	>8 publications with wnt11b-2 and Breast Neoplasms
Disease Models, Animal Antibodies	>7 publications with wnt11b-2 and Disease Models, Animal
Kidney Diseases Antibodies	>7 publications with wnt11b-2 and Kidney Diseases
Hypertension Antibodies	>6 publications with wnt11b-2 and Hypertension
Nervous System Diseases Antibodies	>6 publications with wnt11b-2 and Nervous System Diseases
Inflammation Antibodies	>5 publications with wnt11b-2 and Inflammation
Neural Tube Defects Antibodies	>5 publications with wnt11b-2 and Neural Tube Defects
Adenocarcinoma Antibodies	>5 publications with wnt11b-2 and Adenocarcinoma
Necrosis Antibodies	>4 publications with wnt11b-2 and Necrosis
Prostatic Diseases Antibodies	>3 publications with wnt11b-2 and Prostatic Diseases

Organs/Tissues associated with wnt11b-2 recombinant protein

Organ/Tissue Name	Pubmed Publications
Whole Body Antibodies	>3 publications with wnt11b-2 and Whole Body