Human GPN1 Recombinant Protein – Cat# MBS144994

GPN-Loop Gtpase 1 (GPN1) Human Recombinant Protein

Name: GPN1 Recombinant Protein; GPN-Loop Gtpase 1; Human; MyBioSource
Brand: MyBioSource
SKU: MBS144994
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS144994

Description: GPN1 Human Recombinant produced in E Coli is a single polypeptide chain containing 398 amino acids (1-374) and having a molecular mass of 44.3 kDa.GPN1 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic… More details

$250 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GPN-loop GTPase 1 (GPN1), Recombinant Protein

Full Product Name

Recombinant Human GPN-loop GTPase 1

Product Gene Name

GPN1 recombinant protein

Product Synonym Names

GPN1 Human; GPN-loop GTPase 1 Human Recombinant; GPN-loop GTPase 1; XPA binding protein 1 GTPase; RNA polymerase II associated protein 4; MBD2-interacting protein; MBDin; ATP(GTP)-binding protein; XAB1; ATPBD1A; NTPBP; RPAP4

Sequence

MGSSHHH HHH SSGLVPRGSH MGSHMA ASAA AAELQASGGP RHPVCLLVLG MAGSGKTTFV QRLTGHLHAQ GTPPYVINLD PAVHEVPFPA NIDIRDTVKY KEVMKQYGLG PNGGIVTSLN LFATRFDQVM KFIEKAQNMS KYVLIDTPGQ IEVFTWSASG TIITEALASS FPTVVIYVMD TSRSTNPVTF MSNMLYACSI LYKTKLPFIV VMNKTDIIDH SFAVEWMQDF EAFQDALNQE TTYVSNLTRS MSLVLDEFYS SLRVVGVSAV LGTGLDELFV QVTSAAEEYE REYRPEYERL KKSLANAESQ QQREQLERLR KDMGSVALDA GTAKDSLSPV LHPSDLILTR GTLDEEDEEA DSDTDDIDHR VTEESHEEPA FQNFMQESMA QYWKRNNK

Host

E Coli

Form/Format

The GPN1 solution (1mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 50mM NaCl, 1mM DTT and 10% glycerol.
Sterile Filtered colorless solution.

Purity/Purification

Greater than 90% as determined by SDS-PAGE.

Molecular Weight

43,345 Da

OMIM

611479

3D Structure

ModBase 3D Structure for Q9HCN4

Product Categories/Family for GPN1 recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins

Other Notes

Small volumes of GPN1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GPN1 purchase

MBS144994 is a recombinant protein targeting GPN1. Also known as Recombinant Human GPN-loop GTPase 1. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for GPN1. It may not necessarily be applicable to this product.

NCBI GI #

223005899

NCBI GeneID

11321

NCBI Accession #

NP_001138519.1

UniProt Primary Accession #

Q9HCN4

UniProt Secondary Accession #

O76004; B4DQJ5; B4DQM4; B4DXU4; B5MBZ5

UniProt Related Accession #

Q9HCN4

GenBank Nucleotide #

NM_001145047.1

NCBI Official Full Name

GPN-loop GTPase 1 isoform b

NCBI Official Synonym Full Names

GPN-loop GTPase 1

NCBI Official Symbol

GPN1

NCBI Official Synonym Symbols

XAB1; MBDIN; NTPBP; RPAP4; ATPBD1A

UniProt Protein Name

GPN-loop GTPase 1

UniProt Synonym Protein Names

MBD2-interacting protein; XPA-binding protein 1

Protein Family

GPN-loop GTPase

UniProt Gene Name

GPN1

UniProt Synonym Gene Names

MBDin

UniProt Entry Name

GPN1_HUMAN

NCBI Protein Information

GPN-loop GTPase 1; ATP(GTP)-binding protein; MBD2-interacting protein; RNA polymerase II associated protein 4; RNAPII-associated protein 4; XPA binding protein 1, GTPase

NCBI Summary for GPN1

This gene encodes a guanosine triphosphatase enzyme. The encoded protein may play a role in DNA repair and may function in activation of transcription. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009]

UniProt Comments for GPN1

GPN1: Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation. May be involved in nuclear localization of XPA. Belongs to the GPN-loop GTPase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Hydrolase

Chromosomal Location of Human Ortholog: 2p23.3

Cellular Component: cytoplasm; nucleus

Molecular Function: GTPase activity; protein binding; GTP binding

Biological Process: metabolic process

Research Articles on GPN1

1. Gpn1-Gpn3 interaction was essential to maintain steady-state protein levels of both GTPases

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with GPN1 recombinant protein

Reference Product	PubMed Publications
GPN3 recombinant protein	>3 publications with GPN1 and GPN3
XPA recombinant protein	>2 publications with GPN1 and XPA
GPN2 recombinant protein	>1 publications with GPN1 and GPN2
RPAP2 recombinant protein	>1 publications with GPN1 and RPAP2

Organs/Tissues associated with GPN1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Skin Antibodies	>1 publications with GPN1 and Skin