Human MAPRE2 Recombinant Protein – Cat# MBS145000

Microtubule-Associated (MAPRE2) Human Recombinant Protein

Name: MAPRE2 Recombinant Protein; Microtubule-Associated; Human; MyBioSource
Brand: MyBioSource
SKU: MBS145000
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS145000

Description: MAPRE2 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 347 amino acids (1-327 a.a.) and having a molecular mass of 39.2kDa.MAPRE2 is fused to a 20 amino acid His-tag at N-terminus & purified by… More details

$250 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Microtubule-Associated (MAPRE2), Recombinant Protein

Full Product Name

Recombinant Human Microtubule-Associated Protein, RP/EB Family, Member 2

Product Gene Name

MAPRE2 recombinant protein

Product Synonym Names

MAPRE2 Human; Microtubule-Associated Protein, RP/EB Family, Member 2 Human Recombinant; Microtubule-associated protein RP/EB family member 2; APC-binding protein EB2; End-binding protein 2; EB2; MAPRE2; RP1; EB1

Sequence

MGSSHHH HHH SSGLVPRGSH MPGPTQTLSP NGENNNDIIQ DNNGTIIPFR KHTVRGERSY SWGMAVNVYS TSITQETMSR HDIIAWVNDI VSLNYTKVEQ LCSGAAYCQF MDMLFPGCIS LKKVKFQAKL EHEYIHNFKL LQASFKRMNV DKVIPVEKLV KGRFQDNLDF IQWFKKFYDA NYDGKEYDPV EARQGQDAIP PPDPGEQIFN LPKKSHHANS PTAGAAKSSP AAKPGSTPSR PSSAKRASSS GSASKSDKDL ETQVIQLNEQ VHSLKLALEG VEKERDFYFG KLREIELLCQ EHGQENDDLV QRLMDILYAS EEHEGHTEEP EAEEQAHEQQ PPQQEEY

Host

E Coli

Form/Format

MAPRE2 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl and 1mM DTT.
Sterile Filtered clear solution.

Purity/Purification

Greater than 85% as determined by SDS-PAGE.

Preparation and Storage

Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

Molecular Weight

30,691 Da

OMIM

605789

3D Structure

ModBase 3D Structure for Q15555

Product Categories/Family for MAPRE2 recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins; Microtubule-Associated Protein

Other Notes

Small volumes of MAPRE2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MAPRE2 purchase

MBS145000 is a recombinant protein targeting MAPRE2. Also known as Recombinant Human Microtubule-Associated Protein, RP/EB Family, Member 2. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for MAPRE2. It may not necessarily be applicable to this product.

NCBI GI #

219842325

NCBI GeneID

10982

NCBI Accession #

NP_001137298.1

UniProt Primary Accession #

Q15555

UniProt Secondary Accession #

Q9UQ33; B2RE21; B3KR39; B4DJV4; B7Z2L3; E9PHR3; F5H1V8; G5E9I6

UniProt Related Accession #

Q15555

GenBank Nucleotide #

NM_001143826.2

NCBI Official Full Name

microtubule-associated protein RP/EB family member 2 isoform 2

NCBI Official Synonym Full Names

microtubule-associated protein, RP/EB family, member 2

NCBI Official Symbol

MAPRE2

NCBI Official Synonym Symbols

EB1; EB2; RP1

UniProt Protein Name

Microtubule-associated protein RP/EB family member 2

UniProt Synonym Protein Names

APC-binding protein EB2; End-binding protein 2; EB2

Protein Family

Microtubule-associated protein RP/EB family

UniProt Gene Name

MAPRE2

UniProt Synonym Gene Names

RP1; EB2

UniProt Entry Name

MARE2_HUMAN

NCBI Protein Information

microtubule-associated protein RP/EB family member 2; APC-binding protein EB1; APC-binding protein EB2; T-cell activation protein, EB1 family; end-binding protein 2

NCBI Summary for MAPRE2

The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. This protein is a microtubule-associated protein that is necessary for spindle symmetry during mitosis. It is thought to play a role in the tumorigenesis of colorectal cancers and the proliferative control of normal cells. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]

UniProt Comments for MAPRE2

RP1: shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. Its function is unknown; however, its homology suggests involvement in tumorigenesis of colorectal cancers and proliferative control of normal cells. This gene may belong to the intermediate/early gene family, involved in the signal transduction cascade downstream of the TCR.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 18q12.1

Cellular Component: microtubule cytoskeleton; cytoplasm

Molecular Function: microtubule binding

Biological Process: cell proliferation; mitosis; cell division; signal transduction

Research Articles on MAPRE2

1. EB2 is evidently important for initial microtubule reorganisation during epithelial polarisation, whereas its downregulation facilitates EB1 and ACF7 microtubule lattice association, microtubule-actin filament co-alignment and bundle formation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with MAPRE2 recombinant protein

Reference Product	PubMed Publications
CLASP2 recombinant protein	>1 publications with MAPRE2 and CLASP2

Diseases associated with MAPRE2 recombinant protein

Disease Name	Pubmed Publications
Abnormalities, Drug-Induced Antibodies	>1 publications with MAPRE2 and Abnormalities, Drug-Induced

Organs/Tissues associated with MAPRE2 recombinant protein

Organ/Tissue Name	Pubmed Publications
Eye Antibodies	>2 publications with MAPRE2 and Eye
Blood Antibodies	>2 publications with MAPRE2 and Blood
Lung Antibodies	>1 publications with MAPRE2 and Lung
Intestine Antibodies	>1 publications with MAPRE2 and Intestine
Nerve Antibodies	>1 publications with MAPRE2 and Nerve
Kidney Antibodies	>1 publications with MAPRE2 and Kidney