Human CLTB Recombinant Protein – Cat# MBS145065

Clathrin (CLTB) Human Recombinant Protein

Name: CLTB Recombinant Protein; Clathrin; Human; MyBioSource
Brand: MyBioSource
SKU: MBS145065
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS145065

Description: CLTB Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 234 amino acids (1-211 a.a) and having a molecular mass of 25.6kDa (Molecular size on SDS-PAGE will appear higher).CLTB is fused to a 23 amino… More details

$250 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Clathrin (CLTB), Recombinant Protein

Full Product Name

Recombinant Human Clathrin, Light Chain B

Product Gene Name

CLTB recombinant protein

Product Synonym Names

CLTB Human; Clathrin, Light Chain B Human Recombinant; Clathrin light chain B; Lcb; CLTB

Sequence

MGSSHHH HHH SSGLVPRGSH MGSMAD DFGF FSSSESGAPE AAEEDPAAAF LAQQESEIAG IENDEGFGAP AGSHAAPAQP GPTSGAGSED MGTTVNGDVF QEANGPADGY AAIAQADRLT QEPESIRKWR EEQRKRLQEL DAASKVTEQE WREKAKKDLE EWNQRQSEQV EKNKINNRAS EEAFVKESKE ETPGTEWEKV AQLCDFNPKS SKQCKDVSRL RSVLMSLKQT PLSR.

Host

E Coli

Form/Format

CLTB protein solution (1mg/ml) containing 20mM Tris-HCl buffer, pH8.0, 10% glycerol, 0.2mM PMSF and 100mM NaCl.
Sterile Filtered colorless solution.

Purity/Purification

Greater than 85.0% as determined by SDS-PAGE.

Preparation and Storage

Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

Molecular Weight

23,181 Da

OMIM

118970

3D Structure

ModBase 3D Structure for P09497

Product Categories/Family for CLTB recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins; Clathrin

Other Notes

Small volumes of CLTB recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CLTB purchase

MBS145065 is a recombinant protein targeting CLTB. Also known as Recombinant Human Clathrin, Light Chain B. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for CLTB. It may not necessarily be applicable to this product.

NCBI GI #

4502901

NCBI GeneID

1212

NCBI Accession #

NP_001825.1

UniProt Primary Accession #

P09497

UniProt Secondary Accession #

Q53Y37; Q6FHW1

UniProt Related Accession #

P09497

GenBank Nucleotide #

NM_001834.3

NCBI Official Full Name

clathrin light chain B isoform a

NCBI Official Synonym Full Names

clathrin, light chain B

NCBI Official Symbol

CLTB

NCBI Official Synonym Symbols

LCB

UniProt Protein Name

Clathrin light chain B

Protein Family

Clathrin

UniProt Gene Name

CLTB

UniProt Synonym Gene Names

Lcb

UniProt Entry Name

CLCB_HUMAN

NCBI Protein Information

clathrin light chain B; clathrin, light chain (Lcb); clathrin, light polypeptide (Lcb)

NCBI Summary for CLTB

Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]

UniProt Comments for CLTB

CLTB: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Clathrin coats are formed from molecules containing 3 heavy chains and 3 light chains. Interacts (via N-terminus) with HIP1. Interacts with HIP1R. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 5q35

Cellular Component: clathrin coat of trans-Golgi network vesicle; clathrin coat; intracellular membrane-bound organelle; cytoplasm; plasma membrane; trans-Golgi network; clathrin coat of coated pit

Molecular Function: protein binding; structural molecule activity; peptide binding

Biological Process: vesicle-mediated transport; intracellular protein transport

Research Articles on CLTB

1. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CLTB recombinant protein

Reference Product	PubMed Publications
CLTA recombinant protein	>5 publications with CLTB and CLTA
CLTC recombinant protein	>2 publications with CLTB and CLTC

Pathways associated with CLTB recombinant protein

Products by Pathway	Pathway Diagram
Arf1 Pathway antibodies	Arf1 Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Bacterial Invasion Of Epithelial Cells Pathway antibodies	Bacterial Invasion Of Epithelial Cells Pathway Diagram
Bacterial Invasion Of Epithelial Cells Pathway antibodies	Bacterial Invasion Of Epithelial Cells Pathway Diagram
Developmental Biology Pathway antibodies	Developmental Biology Pathway Diagram
EPH-Ephrin Signaling Pathway antibodies	EPH-Ephrin Signaling Pathway Diagram
EPH-ephrin Mediated Repulsion Of Cells Pathway antibodies	EPH-ephrin Mediated Repulsion Of Cells Pathway Diagram
Endocrine And Other Factor-regulated Calcium Reabsorption Pathway antibodies	Endocrine And Other Factor-regulated Calcium Reabsorption Pathway Diagram
Endocrine And Other Factor-regulated Calcium Reabsorption Pathway antibodies	Endocrine And Other Factor-regulated Calcium Reabsorption Pathway Diagram
Endocytosis Pathway antibodies	Endocytosis Pathway Diagram

Diseases associated with CLTB recombinant protein

Disease Name	Pubmed Publications
Skin Diseases Antibodies	>1 publications with CLTB and Skin Diseases
Neoplasms, Experimental Antibodies	>1 publications with CLTB and Neoplasms, Experimental
Kidney Diseases Antibodies	>1 publications with CLTB and Kidney Diseases
Liver Diseases Antibodies	>1 publications with CLTB and Liver Diseases

Organs/Tissues associated with CLTB recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>16 publications with CLTB and Blood
Lung Antibodies	>3 publications with CLTB and Lung
Liver Antibodies	>3 publications with CLTB and Liver
Muscle Antibodies	>3 publications with CLTB and Muscle
Brain Antibodies	>3 publications with CLTB and Brain
Heart Antibodies	>2 publications with CLTB and Heart
Kidney Antibodies	>2 publications with CLTB and Kidney
Vascular Antibodies	>1 publications with CLTB and Vascular
Bone Marrow Antibodies	>1 publications with CLTB and Bone Marrow
Prostate Antibodies	>1 publications with CLTB and Prostate