Human ANXA13 Recombinant Protein – Cat# MBS145086

Annexin A13 (ANXA13) Human Recombinant Protein

Name: ANXA13 Recombinant Protein; Annexin A13; Human; MyBioSource
Brand: MyBioSource
SKU: MBS145086
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS145086

Description: ANXA13 Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E Coli is a single, non-glycosylated, polypeptide chain containing 336 amino acids (1-316 a.a.) and having a molecular mass of 37.5kDa. The ANXA13 is purified… More details

$250 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Annexin A13 (ANXA13), Recombinant Protein

Full Product Name

Recombinant Human Annexin A13

Product Gene Name

ANXA13 recombinant protein

Product Synonym Names

ANXA13 Human; Annexin A13 Human Recombinant; Annexin A13; Annexin XIII; Annexin-13; Intestine-specific annexin; ISA; ANXA13; ANX13; MGC150460

Sequence

MGSSHHH HHH SSGLVPRGSH MGNRHAKASS PQGFDVDRDA KKLNKACKGM GTNEAAIIEI LSGRTSDERQ QIKQKYKATY GKELEEVLKS ELSGNFEKTA LALLDRPSEY AARQLQKAMK GLGTDESVLI EVLCTRTNKE IIAIKEAYQR LFDRSLESDV KGDTSGNLKK ILVSLLQANR NEGDDVDKDL AGQDAKDLYD AGEGRWGTDE LAFNEVLAKR SYKQLRATFQ AYQILIGKDI EEAIEEETSG DLQKAYLTLV RCAQDCEDYF AERLYKSMKG AGTDEETLIR IVVTRAEVDL QGIKAKFQEK YQKSLSDMVR SDTSGDFRKL LVALLH

Host

E Coli

Form/Format

The ANXA13 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 30% glycerol, 0.1M NaCl and 1mM EDTA.
Sterile filtered colorless solution.

Purity/Purification

Greater than 90.0% as determined by SDS-PAGE.

Molecular Weight

39,744 Da

OMIM

602573

3D Structure

ModBase 3D Structure for P27216

Product Categories/Family for ANXA13 recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins; Annexin

Other Notes

Small volumes of ANXA13 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ANXA13 purchase

MBS145086 is a recombinant protein targeting ANXA13. Also known as Recombinant Human Annexin A13. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for ANXA13. It may not necessarily be applicable to this product.

NCBI GI #

51896029

NCBI GeneID

312

NCBI Accession #

NP_001003954.1

UniProt Primary Accession #

P27216

UniProt Secondary Accession #

Q9BQR5

UniProt Related Accession #

P27216

GenBank Nucleotide #

NM_001003954.1

NCBI Official Full Name

annexin A13 isoform b

NCBI Official Synonym Full Names

annexin A13

NCBI Official Symbol

ANXA13

NCBI Official Synonym Symbols

ISA; ANX13

UniProt Protein Name

Annexin A13

UniProt Synonym Protein Names

Annexin XIII; Annexin-13; Intestine-specific annexin; ISA

Protein Family

Annexin

UniProt Gene Name

ANXA13

UniProt Synonym Gene Names

ANX13; ISA

UniProt Entry Name

ANX13_HUMAN

NCBI Protein Information

annexin A13; annexin XIII; annexin, intestine-specific; annexin-13; intestine-specific annexin

NCBI Summary for ANXA13

This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. The specific function of this gene has not yet been determined; however, it is associated with the plasma membrane of undifferentiated, proliferating endothelial cells and differentiated villus enterocytes. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

UniProt Comments for ANXA13

ANXA13: a calcium/phospholipid-binding protein associated with the cell membrane. ANXA13 is the probable common ancestor of the annexin family of proteins. Annexins all bind to phospholipids in a calcium-dependent manner. There are at least ten different annexins in mammalian species. Annexins do not contain signal peptides, yet some annexins (A1, A2 and A5) appear to be secreted in a physiologically regulated fashion.

Protein type: Lipid-binding; Calcium-binding

Chromosomal Location of Human Ortholog: 8q24.13

Cellular Component: nucleoplasm; extracellular space; basolateral plasma membrane; apical plasma membrane; plasma membrane; lipid raft

Molecular Function: calcium-dependent phospholipid binding; phosphatidylserine binding; calcium ion binding; phosphatidylcholine binding

Biological Process: negative regulation of Golgi to plasma membrane protein transport; positive regulation of Golgi to plasma membrane protein transport; cell differentiation

Research Articles on ANXA13

1. Ectopic overexpression of Annexin A13 was likewise sufficient to sensitize malignant breast cancer cells to treatment with Rapamycin.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ANXA13 recombinant protein

Reference Product	PubMed Publications
EXT1 recombinant protein	>2 publications with ANXA13 and EXT1
TRPS1 recombinant protein	>1 publications with ANXA13 and TRPS1
CSMD3 recombinant protein	>1 publications with ANXA13 and CSMD3

Diseases associated with ANXA13 recombinant protein

Disease Name	Pubmed Publications
Death Antibodies	>1 publications with ANXA13 and Death
Nervous System Diseases Antibodies	>1 publications with ANXA13 and Nervous System Diseases
Inflammation Antibodies	>1 publications with ANXA13 and Inflammation

Organs/Tissues associated with ANXA13 recombinant protein

Organ/Tissue Name	Pubmed Publications
Stomach Antibodies	>1 publications with ANXA13 and Stomach
Intestine Antibodies	>1 publications with ANXA13 and Intestine