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Three Prime Repair Exonuclease 2 (TREX2) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS145107

Description: TREX2 produced in E Coli is a single, non-glycosylated polypeptide chain containing 256 amino acids (1-236a.a.) and having a molecular mass of 28.0 kDa. TREX2 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Three Prime Repair Exonuclease 2 (TREX2), Recombinant Protein
Full Product Name
Recombinant Human Three Prime Repair Exonuclease 2
Product Gene Name
Product Synonym Names
TREX2 Human; Three Prime Repair Exonuclease 2 Human Recombinant; Three Prime Repair Exonuclease 2; 3'-5' exonuclease TREX2 long form
Sequence
MGSSHHH HHH SSGLVPRGSH MSEAPRAETF VFLDLEATGL PSVEPEIAEL SLFAVHRSSL ENPEHDESGA LVLPRVLDKL TLCMCPERPF TAKASEITGL SSEGLARCRK AGFDGAVVRT LQAFLSRQAG PICLVAHNGF DYDFPLLCAE LRRLGARLPR DTVCLDTLPA LRGLDRAHSH GTRARGRQGY SLGSLFHRYF RAEPSAAHSA EGDVHTLLLI FLHRAAELLA WADEQARGWA HIEPMYLPPD DPSLEA
Host
E Coli
Form/Format
The TREX2 protein solution (1mg/1ml) is formulated in 20mM Tris-HCl buffer (pH8.0), 200mM NaCl, 5mM DTT and 30% glycerol.
Sterile Filtered clear solution.
Purity/Purification
Greater than 95% as determined by SDS-PAGE.
Molecular Weight
25,922 Da
OMIM
300370
3D Structure
ModBase 3D Structure for Q9BQ50

Product Categories/Family for TREX2 recombinant protein

Other Notes

Small volumes of TREX2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TREX2 purchase

MBS145107 is a recombinant protein targeting TREX2. Also known as Recombinant Human Three Prime Repair Exonuclease 2. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for TREX2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
three prime repair exonuclease 2
NCBI Official Synonym Full Names
three prime repair exonuclease 2
NCBI Official Symbol
TREX2
UniProt Protein Name
Three prime repair exonuclease 2
UniProt Synonym Protein Names
3'-5' exonuclease TREX2
UniProt Gene Name
TREX2
UniProt Entry Name
TREX2_HUMAN
NCBI Protein Information
three prime repair exonuclease 2; 3'-5' exonuclease TREX2 long form

NCBI Summary for TREX2

This gene encodes a nuclear protein with 3' to 5' exonuclease activity. The encoded protein participates in double-stranded DNA break repair, and may interact with DNA polymerase delta. [provided by RefSeq, Nov 2012]

UniProt Comments for TREX2

TREX2: Exonuclease with a preference for double stranded DNA with mismatched 3' termini. May play a role in DNA repair. Belongs to the exonuclease superfamily. TREX family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.11.2; DNA repair, damage; Deoxyribonuclease

Chromosomal Location of Human Ortholog: Xq28

Cellular Component: nucleus

Molecular Function: protein homodimerization activity; nucleic acid binding; 3'-5'-exodeoxyribonuclease activity; magnesium ion binding; exodeoxyribonuclease III activity

Biological Process: DNA repair; DNA catabolic process, exonucleolytic; DNA metabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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