Human BDH1 Recombinant Protein – Cat# MBS145116

3-Hydroxybutyrate Dehydrogenase (BDH1) Human Recombinant Protein

Name: BDH1 Recombinant Protein; 3-Hydroxybutyrate Dehydrogenase; Human; MyBioSource
Brand: MyBioSource
SKU: MBS145116
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS145116

Description: BDH1 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 318 amino acids (47-343) and having a molecular mass of 35.3kDa.BDH1 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary… More details

$250 / 0.001 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

3-Hydroxybutyrate Dehydrogenase (BDH1), Recombinant Protein

Full Product Name

Recombinant Human 3-Hydroxybutyrate Dehydrogenase, Type 1

Product Gene Name

BDH1 recombinant protein

Product Synonym Names

BDH1 Human; 3-Hydroxybutyrate Dehydrogenase, Type 1 Human Recombinant; D-beta-hydroxybutyrate dehydrogenase; mitochondrial; BDH; 3-hydroxybutyrate dehydrogenase; BDH1; SDR9C1

Sequence

MGSSHHH HHH SSGLVPRGSH MASAAE PVGS KAVLVTGCDS GFGFSLAKHL HSKGFLVFAG CLMKDKGHDG VKELDSLNSD RLRTVQLNVC SSEEVEKVVE IVRSSLKDPE KGMWGLVNNA GISTFGEVEF TSLETYKQVA EVNLWGTVRM TKSFLPLIRR AKGRVVNISS MLGRMANPAR SPYCITKFGV EAFSDCLRYE MYPLGVKVSV VEPGNFIAAT SLYSPESIQA IAKKMWEELP EVVRKDYGKK YFDEKIAKME TYCSSGSTDT SPVIDAVTHA LTATTPYTRY HPMDYYWWLR MQIMTHLPGA ISDMIYIR.< /u>

Host

E Coli

Form/Format

The BDH1 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 30% glycerol, 0.2M NaCl, 2mM DTT and 0.1mM PMSF.
Sterile Filtered colorless solution.

Purity/Purification

Greater than 85% as determined by SDS-PAGE.

Molecular Weight

38,157 Da

OMIM

603063

3D Structure

ModBase 3D Structure for Q02338

Product Categories/Family for BDH1 recombinant protein

Enzymes; Dehydrogenase

Other Notes

Small volumes of BDH1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BDH1 purchase

MBS145116 is a recombinant protein targeting BDH1. Also known as Recombinant Human 3-Hydroxybutyrate Dehydrogenase, Type 1. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for BDH1. It may not necessarily be applicable to this product.

NCBI GI #

17738292

NCBI GeneID

622

NCBI Accession #

NP_004042.1

UniProt Primary Accession #

Q02338

UniProt Secondary Accession #

Q96ET1; Q9BRZ4; D3DXC0

UniProt Related Accession #

Q02338

GenBank Nucleotide #

NM_004051.4

NCBI Official Full Name

D-beta-hydroxybutyrate dehydrogenase, mitochondrial

NCBI Official Synonym Full Names

3-hydroxybutyrate dehydrogenase, type 1

NCBI Official Symbol

BDH1

NCBI Official Synonym Symbols

BDH; SDR9C1

UniProt Protein Name

D-beta-hydroxybutyrate dehydrogenase, mitochondrial

UniProt Synonym Protein Names

3-hydroxybutyrate dehydrogenase; Short chain dehydrogenase/reductase family 9C member 1

Protein Family

(R,R)-butanediol dehydrogenase

UniProt Gene Name

BDH1

UniProt Synonym Gene Names

BDH; SDR9C1; BDH

UniProt Entry Name

BDH_HUMAN

NCBI Protein Information

D-beta-hydroxybutyrate dehydrogenase, mitochondrial; (R)-3-hydroxybutyrate dehydrogenase; 3-hydroxybutyrate dehydrogenase (heart, mitochondrial); short chain dehydrogenase/reductase family 9C member 1; short chain dehydrogenase/reductase family 9C, member 1

NCBI Summary for BDH1

This gene encodes a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]

UniProt Comments for BDH1

BDH: a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]

Protein type: Mitochondrial; Carbohydrate Metabolism - butanoate; Oxidoreductase; EC 1.1.1.30; Lipid Metabolism - synthesis and degradation of ketone bodies

Chromosomal Location of Human Ortholog: 3q29

Cellular Component: nucleoplasm; mitochondrion; mitochondrial matrix; cytoplasm; mitochondrial inner membrane

Molecular Function: 3-hydroxybutyrate dehydrogenase activity; phospholipid binding

Biological Process: response to drug; response to toxin; cellular lipid metabolic process; ketone body metabolic process; liver development; response to estradiol stimulus; response to insulin stimulus; response to starvation; response to ethanol; response to cadmium ion; ketone body catabolic process; ketone body biosynthetic process; brain development; response to nutrient; response to corticosterone stimulus

Research Articles on BDH1

1. Data show that the ketone body metabolizing enzymes BDH1, BDH2, OXCT1 and ACAT1 were expressed at the mRNA and protein level in all glioma cell lines.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with BDH1 recombinant protein

Reference Product	PubMed Publications
BDH2 recombinant protein	>5 publications with BDH1 and BDH2
OXCT1 recombinant protein	>4 publications with BDH1 and OXCT1
HMGCL recombinant protein	>3 publications with BDH1 and HMGCL

Pathways associated with BDH1 recombinant protein

Products by Pathway	Pathway Diagram
Butanoate Metabolism Pathway antibodies	Butanoate Metabolism Pathway Diagram
Butanoate Metabolism Pathway antibodies	Butanoate Metabolism Pathway Diagram
FOXA2 And FOXA3 Transcription Factor Networks Pathway antibodies	FOXA2 And FOXA3 Transcription Factor Networks Pathway Diagram
Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies	Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
Ketone Body Metabolism Pathway antibodies	Ketone Body Metabolism Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Lipids And Lipoproteins Pathway antibodies	Metabolism Of Lipids And Lipoproteins Pathway Diagram
Synthesis And Degradation Of Ketone Bodies Pathway antibodies	Synthesis And Degradation Of Ketone Bodies Pathway Diagram
Synthesis And Degradation Of Ketone Bodies Pathway antibodies	Synthesis And Degradation Of Ketone Bodies Pathway Diagram

Diseases associated with BDH1 recombinant protein

Disease Name	Pubmed Publications
Fatty Liver Antibodies	>4 publications with BDH1 and Fatty Liver
Breast Neoplasms Antibodies	>2 publications with BDH1 and Breast Neoplasms
Inflammation Antibodies	>2 publications with BDH1 and Inflammation
Cardiovascular Diseases Antibodies	>1 publications with BDH1 and Cardiovascular Diseases
Weight Loss Antibodies	>1 publications with BDH1 and Weight Loss
Neoplasm Metastasis Antibodies	>1 publications with BDH1 and Neoplasm Metastasis
Heart Diseases Antibodies	>1 publications with BDH1 and Heart Diseases

Organs/Tissues associated with BDH1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>5 publications with BDH1 and Blood
Liver Antibodies	>5 publications with BDH1 and Liver
Heart Antibodies	>3 publications with BDH1 and Heart
Muscle Antibodies	>2 publications with BDH1 and Muscle
Brain Antibodies	>2 publications with BDH1 and Brain
Adipose Tissue Antibodies	>1 publications with BDH1 and Adipose Tissue
Prostate Antibodies	>1 publications with BDH1 and Prostate
Mammary Gland Antibodies	>1 publications with BDH1 and Mammary Gland