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Prefoldin Subunit 4 (PFDN4) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS145146

Description: PFDN4 produced in E Coli is a single, non-glycosylated polypeptide chain containing 154 amino acids (1-134.a.a) and having a molecular mass of 17.4kDa. PFDN4 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Prefoldin Subunit 4 (PFDN4), Recombinant Protein
Full Product Name
Recombinant Human Prefoldin Subunit 4
Product Gene Name
Product Synonym Names
PFDN4 Human; Prefoldin Subunit 4 Recombinant Human; Prefoldin Subunit 4; PFD4; C1; Prefoldin 4; Protein C-1
Sequence
MGSSHHH HHH SSGLVPRGSH MAATMKKAAA EDVNVTFEDQ QKINKFARNT SRITELKEEI EVKKKQLQNL EDACDDIMLA DDDCLMIPYQ IGDVFISHSQ EETQEMLEEA KKNLQEEIDA LESRVESIQR VLADLKVQLY AKFGSNINLE ADES
Host
E Coli
Form/Format
The PFDN4 protein solution (1mg/1ml) is formulated in 20 mM Tris-HCl buffer (pH7.5), 50mM NaCl, 1mM DTT and 10% glycerol.
Sterile Filtered clear solution.
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Molecular Weight
15,314 Da
OMIM
604898
3D Structure
ModBase 3D Structure for Q9NQP4

Other Notes

Small volumes of PFDN4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PFDN4 purchase

MBS145146 is a recombinant protein targeting PFDN4. Also known as Recombinant Human Prefoldin Subunit 4. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for PFDN4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
prefoldin subunit 4
NCBI Official Synonym Full Names
prefoldin subunit 4
NCBI Official Symbol
PFDN4
NCBI Official Synonym Symbols
C1; PFD4
UniProt Protein Name
Prefoldin subunit 4
UniProt Synonym Protein Names
Protein C-1
Protein Family
UniProt Gene Name
PFDN4
UniProt Synonym Gene Names
PFD4
UniProt Entry Name
PFD4_HUMAN
NCBI Protein Information
prefoldin subunit 4; prefoldin 4; protein C-1

NCBI Summary for PFDN4

This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. [provided by RefSeq, Jul 2008]
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UniProt Comments for PFDN4

PFDN4: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Belongs to the prefoldin subunit beta family.

Chromosomal Location of Human Ortholog: 20q13.2

Cellular Component: mitochondrion; cytoplasm; cytosol; prefoldin complex; nucleus

Molecular Function: protein binding; chaperone binding; unfolded protein binding

Biological Process: 'de novo' posttranslational protein folding; cellular protein metabolic process; protein folding
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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