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Carcinoma Amplified Sequence 2 (BCAS2) Human Breast Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS145196

Introduction: Pre-mRNA-splicing factor SPF27 (BCAS2) is a ubiquitously expressed nuclear protein that was initially identified as being overexpressed in various breast cancer cell lines. BCAS2 is currently as a component of the spliceosome, participating in… More details

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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
Carcinoma Amplified Sequence 2 (BCAS2), Recombinant Protein
Full Product Name
Recombinant Human Breast Carcinoma Amplified Sequence 2
Product Gene Name
Product Synonym Names
BCAS2 Human; Breast Carcinoma Amplified Sequence 2 Human Recombinant; Pre-mRNA-splicing factor SPF27; Breast carcinoma-amplified sequence 2; DNA amplified in mammary carcinoma 1 protein; Spliceosome-associated protein SPF 27; BCAS2; DAM1; SPF27; Snt309
Sequence
MRGSHHH HHH GMASMTGGQQ MGRDLYDDDD KDRWGS MAGT GLVAGEVVVD ALPYFDQGYE APGVREAAAA LVEEETRRYR PTKNYLSYLT APDYSAFETD IMRNEFERLA ARQPIELLSM KRYELPAPSS GQKNDITAWQ ECVNNSMAQL EHQAVRIENL ELMSQHGCNA WKVYNENLVH MIEHAQKELQ KLRKHIQDLN WQRKNMQLTA GSKLREMESN WVSLVSKNYE IERTIVQLEN EIYQIKQQHG EANKENIRQD F
Host
E Coli
Form/Format
The BCAS2 solution (0.25 mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 20% glycerol, 5mM DTT and 0.2M NaCl.
Sterile Filtered colorless solution.
Purity/Purification
Greater than 85.0% as determined by SDS-PAGE.
Molecular Weight
26,131 Da
OMIM
605783
3D Structure
ModBase 3D Structure for O75934

Other Notes

Small volumes of BCAS2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BCAS2 purchase

MBS145196 is a recombinant protein targeting BCAS2. Also known as Recombinant Human Breast Carcinoma Amplified Sequence 2. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for BCAS2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
pre-mRNA-splicing factor SPF27
NCBI Official Synonym Full Names
breast carcinoma amplified sequence 2
NCBI Official Symbol
BCAS2
NCBI Official Synonym Symbols
DAM1; SPF27; Snt309
UniProt Protein Name
Pre-mRNA-splicing factor SPF27
UniProt Synonym Protein Names
Breast carcinoma-amplified sequence 2; DNA amplified in mammary carcinoma 1 protein; Spliceosome-associated protein SPF 27
UniProt Gene Name
BCAS2
UniProt Synonym Gene Names
DAM1
UniProt Entry Name
SPF27_HUMAN
NCBI Protein Information
pre-mRNA-splicing factor SPF27; DNA amplified in mammary carcinoma 1 protein; breast carcinoma-amplified sequence 2; spliceosome associated protein, amplified in breast cancer; spliceosome-associated protein SPF 27

UniProt Comments for BCAS2

BCAS2: Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. Belongs to the SPF27 family.

Protein type: Spliceosome; RNA splicing; Nucleolus; Nuclear receptor co-regulator

Chromosomal Location of Human Ortholog: 1p13.2

Cellular Component: nucleoplasm; spliceosome; DNA replication factor A complex; nucleolus; cell junction; nucleus

Molecular Function: protein binding

Biological Process: nuclear mRNA splicing, via spliceosome; RNA splicing, via transesterification reactions; RNA splicing; gene expression
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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