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Guanosine Monophosphate Reductase (GMPR) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS145233

Description: GMPR Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 365 amino acids (1-345) and having a molecular mass of 39.5kDa.GMPR is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary… More details

$250 / 0.005 mg +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Guanosine Monophosphate Reductase (GMPR), Recombinant Protein
Full Product Name
Recombinant Human Guanosine Monophosphate Reductase
Product Gene Name
Product Synonym Names
GMPR Human; Guanosine Monophosphate Reductase Human Recombinant; GMP reductase 1; Guanosine 5'-monophosphate oxidoreductase 1; Guanosine monophosphate reductase 1; GMPR; GMPR1
Sequence
MGSSHHH HHH SSGLVPRGSH MPRIDADLKL DFKDVLLRPK RSSLKSRAEV DLERTFTFRN SKQTYSGIPI IVANMDTVGT FEMAAVMSQH SMFTAIHKHY SLDDWKLFAT NHPECLQNVA VSSGSGQNDL EKMTSILEAV PQVKFICLDV ANGYSEHFVE FVKLVRAKFP EHTIMAGNVV TGEMVEELIL SGADIIKVGV GPGSVCTTRT KTGVGYPQLS AVIECADSAH GLKGHIISDG GCTCPGDVAK AFGAGADFVM LGGMFSGHTE CAGEVIERNG RKLKLFYGMS SDTAMNKHAG GVAEYRASEG KTVEVPYKGD VENTILDILG GLRSTCTYVG AAKLKELSRR ATFIRVTQQH NTVFS.
Host
E Coli
Form/Format
The GMPR solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 40% glycerol, 0.15M NaCl and 1mM DTT.
Sterile Filtered clear colorless solution.
Purity/Purification
Greater than 95.0% as determined by SDS-PAGE.
Molecular Weight
37,419 Da
OMIM
139265
3D Structure
ModBase 3D Structure for P36959

Product Categories/Family for GMPR recombinant protein

Other Notes

Small volumes of GMPR recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GMPR purchase

MBS145233 is a recombinant protein targeting GMPR. Also known as Recombinant Human Guanosine Monophosphate Reductase. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for GMPR. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
GMP reductase 1
NCBI Official Synonym Full Names
guanosine monophosphate reductase
NCBI Official Symbol
GMPR
NCBI Official Synonym Symbols
GMPR1
UniProt Protein Name
GMP reductase 1
UniProt Synonym Protein Names
Guanosine 5'-monophosphate oxidoreductase 1; Guanosine monophosphate reductase 1
Protein Family
UniProt Gene Name
GMPR
UniProt Synonym Gene Names
GMPR1; Guanosine monophosphate reductase 1
UniProt Entry Name
GMPR1_HUMAN
NCBI Protein Information
GMP reductase 1; guanine monophosphate reductase; guanosine 5'-monophosphate oxidoreductase 1; guanosine monophosphate reductase 1

NCBI Summary for GMPR

This gene encodes an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of GMP to IMP. The protein also functions in the re-utilization of free intracellular bases and purine nucleosides.[provided by RefSeq, Oct 2009]

UniProt Comments for GMPR

GMPR: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. Belongs to the IMPDH/GMPR family.

Protein type: Nucleotide Metabolism - purine; Oxidoreductase; EC 1.7.1.7

Chromosomal Location of Human Ortholog: 6p23

Cellular Component: cytosol

Molecular Function: GMP reductase activity; metal ion binding

Biological Process: nucleobase, nucleoside and nucleotide metabolic process; nucleotide metabolic process; response to cold; purine base metabolic process; purine salvage
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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