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Platelet-Activating Factor Acetylhydrolase 1b (PAFAH1B3) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS145358

Description: PAFAH1B3 Human Recombinant produced in E Coli is a single polypeptide chain containing 254 amino acids (1-231) and having a molecular mass of 28.2 kDa.PAFAH1B3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary… More details

$250 / 0.005 mg +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
Platelet-activating Factor Acetylhydrolase 1b (PAFAH1B3 ), Recombinant Protein
Full Product Name
Recombinant Human Platelet-activating Factor Acetylhydrolase 1b, Catalytic Subunit 3
Product Synonym Names
PAFAH1B3 Human; Platelet-activating Factor Acetylhydrolase 1b, Catalytic Subunit 3 Human Recombinant; Platelet-activating factor acetylhydrolase 1b catalytic subunit 3 (29kDa); PAF acetylhydrolase 29 kDa subunit; platelet-activating factor acetylhydrolase; isoform Ib gamma subunit (29kD); PAF-AH1b alpha 1 subunit; PAF-AH 29 kDa subunit; PAFAHG; PAFAH subunit gamma; EC 3.1.1.47
Sequence
MGSSHHH HHH SSGLVPRGSH MGSMSG EENP ASKPTPVQDV QGDGRWMSLH HRFVADSKDK EPEVVFIGDS LVQLMHQCEI WRELFSPLHA LNFGIGGDGT QHVLWRLENG ELEHIRPKIV VVWVGTNNHG HTAEQVTGGI KAIVQLVNER QPQARVVVLG LLPRGQHPNP LREKNRQVNE LVRAALAGHP RAHFLDADPG FVHSDGTISH HDMYDYLHLS RLGYTPVCRA LHSLLLRLLA QDQGQGAPLL EPAP
Host
E Coli
Form/Format
The PAFAH1B3 solution (1mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 100mM NaCl and 10% glycerol.
Sterile Filtered colorless solution.
Purity/Purification
Greater than 95% as determined by SDS-PAGE.
Molecular Weight
25,734 Da
OMIM
603074
3D Structure
ModBase 3D Structure for Q15102

Product Categories/Family for PAFAH1B3 recombinant protein

Other Notes

Small volumes of PAFAH1B3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PAFAH1B3 purchase

MBS145358 is a recombinant protein targeting PAFAH1B3 . Also known as Recombinant Human Platelet-activating Factor Acetylhydrolase 1b, Catalytic Subunit 3. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for PAFAH1B3 . It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
platelet-activating factor acetylhydrolase IB subunit gamma
NCBI Official Synonym Full Names
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
NCBI Official Symbol
PAFAH1B3
NCBI Official Synonym Symbols
PAFAHG
UniProt Protein Name
Platelet-activating factor acetylhydrolase IB subunit gamma
UniProt Synonym Protein Names
PAF acetylhydrolase 29 kDa subunit; PAF-AH 29 kDa subunit; PAF-AH subunit gamma; PAFAH subunit gamma
UniProt Gene Name
PAFAH1B3
UniProt Synonym Gene Names
PAFAHG; PAF-AH 29 kDa subunit; PAFAH subunit gamma
UniProt Entry Name
PA1B3_HUMAN
NCBI Protein Information
platelet-activating factor acetylhydrolase IB subunit gamma; PAF acetylhydrolase 29 kDa subunit; PAF-AH 29 kDa subunit; PAF-AH subunit gamma; PAF-AH1b alpha 1 subunit; PAFAH subunit gamma; platelet-activating factor acetylhydrolase, isoform Ib, subunit 3 (29kDa)

NCBI Summary for PAFAH1B3

This gene encodes an acetylhydrolase that catalyzes the removal of an acetyl group from the glycerol backbone of platelet-activating factor. The encoded enzyme is a subunit of the platelet-activating factor acetylhydrolase isoform 1B complex, which consists of the catalytic beta and gamma subunits and the regulatory alpha subunit. This complex functions in brain development. A translocation between this gene on chromosome 19 and the CDC-like kinase 2 gene on chromosome 1 has been observed, and was associated with mental retardation, ataxia, and atrophy of the brain. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009]
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UniProt Comments for PAFAH1B3

PAFAH1B3: Inactivates paf by removing the acetyl group at the sn-2 position. This is a catalytic subunit. Plays an important role during the development of brain. Belongs to the 'GDSL' lipolytic enzyme family. Platelet-activating factor acetylhydrolase IB beta/gamma subunits subfamily.

Protein type: Lipid Metabolism - ether lipid; EC 3.1.1.47; Lipase

Chromosomal Location of Human Ortholog: 19q13.1

Cellular Component: membrane; cytoplasm; cytosol

Molecular Function: protein binding; platelet-activating factor acetyltransferase activity; protein heterodimerization activity; 1-alkyl-2-acetylglycerophosphocholine esterase activity

Biological Process: nervous system development; spermatogenesis; lipid metabolic process; brain development; lipid catabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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