Rat CCL11 Active Protein – Cat# MBS145398

Eotaxin (CCL11) Rat Active Protein

Name: CCL11 Active Protein; Eotaxin; Rat; MyBioSource
Brand: MyBioSource
SKU: MBS145398
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS145398

Description: Eotaxin Rat Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 74 amino acids and having a molecular mass of 8.4kDa. The CCL11 is purified by proprietary chromatographic techniques.Introduction: Chemokine… More details

$250 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Eotaxin (Ccl11), Active Protein

Full Product Name

Recombinant Rat Eotaxin (CCL11)

Product Gene Name

Ccl11 active protein

Product Synonym Names

Eotaxin Rat; Eotaxin Rat Recombinant (CCL11); Small inducible cytokine A11; CCL11; Eosinophil chemotactic protein; chemokine (C-C motif) ligand 11; SCYA11; rEotaxin

Sequence

HPGSIPTSCC FTMTSKKIPN TLLKSYKRIT NNRCTLKAIV FKTKLGKEIC ADPKKKWVQD ATKHLDQKLQ TPKP

Host

E Coli

Form/Format

Filtered (0.2 um) and lyophilized from a concentrated (1mg/ml) solution in in 1xPBS, pH7.4.
Sterile Filtered White lyophilized (freeze-dried) powder.

Purity/Purification

Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

Preparation and Storage

Lyophilized Eotaxin although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution CCL11 should be stored at 4C between 2-7 days and for future use below -18C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

Molecular Weight

10,851 Da

3D Structure

ModBase 3D Structure for P97545

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Solubility

It is recommended to reconstitute the lyophilized Eotaxin in sterile 18M-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.

Biological Activity

Determined by its ability to chemoattract purified blood eosinophils using a concentration range of 0.1-1.0 ug/ml, corresponding to a Specific Activity of 10-100IU/mg.

Product Categories/Family for Ccl11 active protein

Chemokines; Eotaxin

Other Notes

Small volumes of Ccl11 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Ccl11 purchase

MBS145398 is an active protein targeting Ccl11. Also known as Recombinant Rat Eotaxin (CCL11). Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for Ccl11. It may not necessarily be applicable to this product.

NCBI GI #

11276089

NCBI GeneID

29397

NCBI Accession #

NP_062078.1

UniProt Primary Accession #

P97545

UniProt Secondary Accession #

O08780

UniProt Related Accession #

P97545

GenBank Nucleotide #

NM_019205.1

NCBI Official Full Name

eotaxin

NCBI Official Synonym Full Names

chemokine (C-C motif) ligand 11

NCBI Official Symbol

Ccl11

NCBI Official Synonym Symbols

Scya11

UniProt Protein Name

Eotaxin

UniProt Synonym Protein Names

C-C motif chemokine 11; Eosinophil chemotactic protein; Small-inducible cytokine A11

Protein Family

Eotaxin

UniProt Gene Name

Ccl11

UniProt Synonym Gene Names

Scya11

UniProt Entry Name

CCL11_RAT

NCBI Protein Information

eotaxin; C-C motif chemokine 11; eosinophil chemotactic protein; small inducible cytokine A11; small inducible cytokine subfamily A11; small-inducible cytokine A11

NCBI Summary for Ccl11

mouse homolog is an eosinophil chemoattractant [RGD, Feb 2006]

UniProt Comments for Ccl11

In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions.

Research Articles on Ccl11

1. Iddm30 controls pancreatic expression of Ccl11 (Eotaxin) and the Th1/Th2 balance within the insulitic lesions.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Ccl11 active protein

Products by Pathway	Pathway Diagram
Asthma Pathway antibodies	Asthma Pathway Diagram
Asthma Pathway antibodies	Asthma Pathway Diagram
Chemokine Receptors Bind Chemokines Pathway antibodies	Chemokine Receptors Bind Chemokines Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies	Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram

Diseases associated with Ccl11 active protein

Disease Name	Pubmed Publications
Inflammation Antibodies	>703 publications with Ccl11 and Inflammation
Respiratory Tract Diseases Antibodies	>573 publications with Ccl11 and Respiratory Tract Diseases
Hypersensitivity Antibodies	>565 publications with Ccl11 and Hypersensitivity
Asthma Antibodies	>511 publications with Ccl11 and Asthma
Lung Diseases Antibodies	>470 publications with Ccl11 and Lung Diseases
Respiratory Hypersensitivity Antibodies	>411 publications with Ccl11 and Respiratory Hypersensitivity
Necrosis Antibodies	>196 publications with Ccl11 and Necrosis
Bronchial Hyperreactivity Antibodies	>86 publications with Ccl11 and Bronchial Hyperreactivity
Drug Hypersensitivity Antibodies	>82 publications with Ccl11 and Drug Hypersensitivity
Dermatitis, Atopic Antibodies	>60 publications with Ccl11 and Dermatitis, Atopic

Organs/Tissues associated with Ccl11 active protein

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>487 publications with Ccl11 and Lung