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CMRF35-Like Molecule 1 (CD300LF) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1454093

MBS1454093 is a recombinant protein targeting Cd300lf. Also known as Recombinant Mouse CMRF35-like molecule 1 (Cd300lf), partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1295 / 0.5 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CMRF35-like molecule 1 (Cd300lf), Recombinant Protein
Full Product Name
Recombinant Mouse CMRF35-like molecule 1 (Cd300lf), partial
Product Gene Name
Cd300lf recombinant protein
Product Synonym Gene Name
Cd300lf
Sequence
E DPVTGPEEVS GQEQGSLTVQ CRYTSGWKDY KKYWCQGVPQ RSCKTLVETD ASEQLVKKNR VSIRDNQRDF IFTVTMEDLR MSDAGIYWCG ITKGGLDPMF KVTVNIGPAI QVPITVPTMP PITSTTTIFT VTTTVKETSM FPTLTSYYSD NGHGGGDSGG GEDGVGDGFL DLS
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
30,791 Da
Sequence Positions
20-193
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q6SJQ7
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Cd300lf recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Cd300lf. It may not necessarily be applicable to this product.

NCBI GI #
281332121
NCBI GeneID
246746
NCBI Accession #
NP_001162624.1
UniProt Primary Accession #
Q6SJQ7
UniProt Secondary Accession #
Q6PEU7; Q8K4V9; A2A6Z1; A2A6Z3
UniProt Related Accession #
Q6SJQ7
GenBank Nucleotide #
NM_001169153.1
NCBI Official Full Name
CMRF35-like molecule 1 isoform 1
NCBI Official Synonym Full Names
CD300 molecule like family member F
NCBI Official Symbol
Cd300lf
NCBI Official Synonym Symbols
CLM1; CLIM1; CLM-1; Digr2; IREM1; LMIR3; Pigr3; IgSF13; F730004D16Rik
UniProt Protein Name
CMRF35-like molecule 1
UniProt Synonym Protein Names
CD300 antigen-like family member F; Leukocyte mono-Ig-like receptor 3; Myeloid-associated immunoglobulin-like receptor 5; MAIR-5; MAIR-V; CD_antigen: CD300f
Protein Family
CMRF35-like molecule
UniProt Gene Name
Cd300lf
UniProt Synonym Gene Names
Clm1; Lmir3; CLM-1; MAIR-5; MAIR-V
NCBI Protein Information
CMRF35-like molecule 1

UniProt Comments for Cd300lf

Acts as an inhibitory receptor for myeloid cells and mast cells (PubMed:17438331). Positively regulates the phagocytosis of apoptotic cells (efferocytosis) via phosphatidylserine (PS) recognition; recognizes and binds PS as a ligand which is expressed on the surface of apoptotic cells (PubMed:21865548). Plays an important role in the maintenance of immune homeostasis, by promoting macrophage-mediated efferocytosis and by inhibiting dendritic cell-mediated efferocytosis (PubMed:26768664). Negatively regulates Fc epsilon receptor-dependent mast cell activation and allergic responses via binding to ceramide which acts as a ligand (PubMed:23123064). May act as a coreceptor for interleukin 4 (IL-4). Associates with and regulates IL-4 receptor alpha-mediated responses by augmenting IL-4- and IL-13-induced signaling (PubMed:26124135). Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 and TRIF through activation of PTPN6/SHP-1 and PTPN11/SHP-2 (). Inhibits osteoclast formation (PubMed:14662855). Induces macrophage cell death upon engagement (PubMed:18097021).
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Research Articles on Cd300lf

1. Our results indicate that direct interaction of MNV with two cell-surface molecules, CD300lf and CD300ld, dictates permissive noroviral infection.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with Cd300lf recombinant protein

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >2 publications with Cd300lf and Necrosis
 Inflammation Antibodies  >1 publications with Cd300lf and Inflammation
 Neoplasms Antibodies  >1 publications with Cd300lf and Neoplasms
 Cardiovascular Diseases Antibodies  >1 publications with Cd300lf and Cardiovascular Diseases

Organs/Tissues associated with Cd300lf recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >1 publications with Cd300lf and Brain
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