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Low-Density Lipoprotein Receptor-Related Protein 12 (LRP12) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1454844

This gene was identified by its differential expression in cancer cells. The product of this gene is predicted to be a transmembrane protein. The level of this protein was found to be lower in tumor derived cell lines compared to normal cells. This gene was… More details

$1685 / 0.5 mg (E-Coli) +2 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Low-density lipoprotein receptor-related protein 12 (LRP12), Recombinant Protein
Full Product Name
Recombinant Human Low-density lipoprotein receptor-related protein 12 (LRP12), partial
Product Gene Name
LRP12 recombinant protein
Product Synonym Gene Name
LRP12
Sequence
EHSENVHI SGVSTACGET PEQIRAPSGI ITSPGWPSEY PAKINCSWFI RANPGEIITI SFQDFDIQGS RRCNLDWLTI ETYKNIESYR ACGSTIPPPY ISSQDHIWIR FHSDDNISRK GFRLAYFSGK SEEPNCACDQ FRCGNGKCIP EAWKCNNMDE CGDSSDEEIC AKEANPPTAA AFQPCAYNQF QCLSRFTKVY TCLPESLKCD GNIDCLDLGD EIDCDVPTCG QWLKYFYGTF NSPNYPDFYP PGSNCTWLID TGDHRKVILR FTDFKLDGTG YGDYVKIYDG LEENPHKLLR VLTAFDSHAP LTVVSSSGQI RVHFCADKVN AARGFNATYQ VDGFCLPWEI PCGGNWGCYT EQQRCDGYWH CPNGRDETNC TMCQKEEFPC SRNGVCYPRS DRCNYQNHCP NGSDEKNCFF CQPGNFHCKN NRCVFESWVC DSQDDCGDGS DEENCPVIVP TR
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
93,123 Da
Sequence Positions
33-492
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q9Y561
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of LRP12 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LRP12 purchase

MBS1454844 is a recombinant protein targeting LRP12. Also known as Recombinant Human Low-density lipoprotein receptor-related protein 12 (LRP12), partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for LRP12. It may not necessarily be applicable to this product.

NCBI GI #
208973262
NCBI GeneID
29967
NCBI Accession #
NP_001129175.1
UniProt Primary Accession #
Q9Y561
UniProt Secondary Accession #
A8K137; B4DRQ2
UniProt Related Accession #
Q9Y561
GenBank Nucleotide #
NM_001135703.2
NCBI Official Full Name
low-density lipoprotein receptor-related protein 12 isoform b
NCBI Official Synonym Full Names
LDL receptor related protein 12
NCBI Official Symbol
LRP12
NCBI Official Synonym Symbols
ST7
UniProt Protein Name
Low-density lipoprotein receptor-related protein 12
UniProt Synonym Protein Names
Suppressor of tumorigenicity 7 protein
Protein Family
Low-density lipoprotein receptor-related protein
UniProt Gene Name
LRP12
UniProt Synonym Gene Names
ST7; LRP-12
NCBI Protein Information
low-density lipoprotein receptor-related protein 12

NCBI Summary for LRP12

This gene encodes a member of the low-density lipoprotein receptor related protein family. The product of this gene is a transmembrane protein that is differentially expressed in many cancer cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]

UniProt Comments for LRP12

Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor.

Research Articles on LRP12

1. Accumulation of functional promoter-associated allelic variants with impact on the transcriptional regulation of LRP12 provides a new pathomechanism for GGs, i.e. highly differentiated epileptogenic brain tumors

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with LRP12 recombinant protein

 Products by Pathway  Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Diseases Associated With Visual Transduction Pathway antibodies  Diseases Associated With Visual Transduction Pathway Diagram
 Retinoid Metabolism And Transport Pathway antibodies  Retinoid Metabolism And Transport Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Visual Phototransduction Pathway antibodies  Visual Phototransduction Pathway Diagram

Diseases associated with LRP12 recombinant protein

 Disease Name  Pubmed Publications
 Hyperplasia Antibodies  >1 publications with LRP12 and Hyperplasia
 Disease Models, Animal Antibodies  >1 publications with LRP12 and Disease Models, Animal
 Precancerous Conditions Antibodies  >1 publications with LRP12 and Precancerous Conditions
 Congenital Abnormalities Antibodies  >1 publications with LRP12 and Congenital Abnormalities

Organs/Tissues associated with LRP12 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >2 publications with LRP12 and Muscle
 Nerve Antibodies  >1 publications with LRP12 and Nerve
 Ear Antibodies  >1 publications with LRP12 and Ear
 Eye Antibodies  >1 publications with LRP12 and Eye
 Brain Antibodies  >1 publications with LRP12 and Brain
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