Human SNRPB Recombinant Protein – Cat# MBS145492

Small Nuclear Ribonucleoprotein (SNRPB) Human Recombinant Protein

Name: SNRPB Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS145492
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS145492

Description: SNRPB Human Recombinant produced in SF9 is a glycosylated, polypeptide chain having a calculated molecular mass of 25.4 kDa which migrates at 30 kDa on SDS-PAGE.SNRPB is expressed with a -6x His tag at N-terminus and purified by proprietary… More details

$250 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Small Nuclear Ribonucleoprotein (SNRPB), Recombinant Protein

Full Product Name

Recombinant Human Small Nuclear Ribonucleoprotein Polypeptides B & B1

Product Gene Name

SNRPB recombinant protein

Product Synonym Names

SNRPB Human; Small Nuclear Ribonucleoprotein Polypeptides B & B1 Human Recombinant; Small nuclear ribonucleoprotein-associated proteins B and B'; snRNP-B; Sm protein B/B'; Sm-B/B'; SmB/B'; SNRPB; COD; SNRPB1; SmB/SmB'

Host

Sf9 Insect Cells

Form/Format

1.16 mg/mL SNRPB is supplied in 20mM HEPES buffer pH 7.5, 0.01 mM EDTA and 0.02% SDS.

Purity/Purification

Greater than 95.0% as determined by SDS-PAGE.

Preparation and Storage

Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
Avoid multiple freeze-thaw cycles.

Molecular Weight

30,032 Da

OMIM

182282

3D Structure

ModBase 3D Structure for P14678

Physical Appearance

Sterile filtered clear solution.

Product Categories/Family for SNRPB recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins; Small Nuclear Ribonucleoprotein Polypeptide

Other Notes

Small volumes of SNRPB recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SNRPB purchase

MBS145492 is a recombinant protein targeting SNRPB. Also known as Recombinant Human Small Nuclear Ribonucleoprotein Polypeptides B & B1. Host: Sf9 Insect Cells.

Additional Details

NCBI/Uniprot data below describe general gene information for SNRPB. It may not necessarily be applicable to this product.

NCBI GI #

4507125

NCBI GeneID

6628

NCBI Accession #

NP_003082.1

UniProt Primary Accession #

P14678

UniProt Secondary Accession #

Q15490; Q6IB35; Q9UIS5

UniProt Related Accession #

P14678

GenBank Nucleotide #

NM_003091.3

NCBI Official Full Name

small nuclear ribonucleoprotein-associated proteins B and B' isoform B

NCBI Official Synonym Full Names

small nuclear ribonucleoprotein polypeptides B and B1

NCBI Official Symbol

SNRPB

NCBI Official Synonym Symbols

COD; SNRPB1; SmB/B'; Sm-B/B'; snRNP-B; SmB/SmB'

UniProt Protein Name

Small nuclear ribonucleoprotein-associated proteins B and B'

UniProt Synonym Protein Names

Sm protein B/B'; Sm-B/B'; SmB/B'

Protein Family

Small nuclear ribonucleoprotein-associated protein

UniProt Gene Name

SNRPB

UniProt Synonym Gene Names

COD; SNRPB1; snRNP-B; Sm-B/B'; SmB/B'

UniProt Entry Name

RSMB_HUMAN

NCBI Protein Information

small nuclear ribonucleoprotein-associated proteins B and B'; B polypeptide of Sm protein; Sm protein B/B'; sm-B/Sm-B'; small nuclear ribonucleoprotein polypeptide B; small nuclear ribonucleoprotein polypeptides B and B'

NCBI Summary for SNRPB

The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene. [provided by RefSeq, Jul 2008]

UniProt Comments for SNRPB

snRNP B1: Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Associated with snRNP U1, U2, U4/U6 and U5. May have a functional role in the pre-mRNA splicing or in snRNP structure. Binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner. Belongs to the snRNP SmB/SmN family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA splicing; Spliceosome; RNA-binding; RNA processing

Chromosomal Location of Human Ortholog: 20p13

Cellular Component: small nuclear ribonucleoprotein complex; nucleoplasm; spliceosome; snRNP U1; cytosol; U12-dependent spliceosome

Molecular Function: protein binding

Biological Process: transcription from RNA polymerase II promoter; nuclear mRNA splicing, via spliceosome; spliceosomal snRNP biogenesis; RNA splicing; histone mRNA metabolic process; gene expression; mRNA 3'-end processing; termination of RNA polymerase II transcription

Research Articles on SNRPB

1. Highly mobile SmB protein-trafficking vesicles in neural cells are dependent on the cellular levels of SMN and SmB for their morphology and mobility.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with SNRPB recombinant protein

Reference Product	PubMed Publications
SNRPE recombinant protein	>51 publications with SNRPB and SNRPE
SNRPF recombinant protein	>50 publications with SNRPB and SNRPF
SNRPD1 recombinant protein	>5 publications with SNRPB and SNRPD1
SNRPD3 recombinant protein	>4 publications with SNRPB and SNRPD3

Pathways associated with SNRPB recombinant protein

Products by Pathway	Pathway Diagram
Cleavage Of Growing Transcript In The Termination Region Pathway antibodies	Cleavage Of Growing Transcript In The Termination Region Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
Metabolism Of Non-coding RNA Pathway antibodies	Metabolism Of Non-coding RNA Pathway Diagram
Processing Of Capped Intron-Containing Pre-mRNA Pathway antibodies	Processing Of Capped Intron-Containing Pre-mRNA Pathway Diagram
Processing Of Capped Intronless Pre-mRNA Pathway antibodies	Processing Of Capped Intronless Pre-mRNA Pathway Diagram
RNA Polymerase II Transcription Pathway antibodies	RNA Polymerase II Transcription Pathway Diagram
RNA Polymerase II Transcription Termination Pathway antibodies	RNA Polymerase II Transcription Termination Pathway Diagram
SLBP Dependent Processing Of Replication-Dependent Histone Pre-mRNAs Pathway antibodies	SLBP Dependent Processing Of Replication-Dependent Histone Pre-mRNAs Pathway Diagram
SLBP Independent Processing Of Histone Pre-mRNAs Pathway antibodies	SLBP Independent Processing Of Histone Pre-mRNAs Pathway Diagram
Sm Core Complex Pathway antibodies	Sm Core Complex Pathway Diagram

Diseases associated with SNRPB recombinant protein

Disease Name	Pubmed Publications
Skin Diseases Antibodies	>2 publications with SNRPB and Skin Diseases
Nervous System Diseases Antibodies	>2 publications with SNRPB and Nervous System Diseases
Breast Neoplasms Antibodies	>1 publications with SNRPB and Breast Neoplasms
Disease Models, Animal Antibodies	>1 publications with SNRPB and Disease Models, Animal

Organs/Tissues associated with SNRPB recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>15 publications with SNRPB and Blood
Brain Antibodies	>9 publications with SNRPB and Brain
Nerve Antibodies	>6 publications with SNRPB and Nerve
Heart Antibodies	>6 publications with SNRPB and Heart
Spleen Antibodies	>5 publications with SNRPB and Spleen
Connective Tissue Antibodies	>2 publications with SNRPB and Connective Tissue
Muscle Antibodies	>2 publications with SNRPB and Muscle
Embryonic Tissue Antibodies	>2 publications with SNRPB and Embryonic Tissue
Lymph Antibodies	>1 publications with SNRPB and Lymph
Lymph Node Antibodies	>1 publications with SNRPB and Lymph Node