Human F2 Recombinant Protein – Cat# MBS145589

Thrombin (F2) Human Recombinant Protein

Name: F2 Recombinant Protein; Thrombin; Human; MyBioSource
Brand: MyBioSource
SKU: MBS145589
Price: 375 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS145589

Description: Recombinant Human Thrombin produced in HEK cells, having a total molecular weight of 36kDa. The Thrombin is purified by proprietary chromatographic techniques.Introduction: Thrombin enzyme (Activated Factor IIa) is an important clotting promoter… More details

$375 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Thrombin (F2), Recombinant Protein

Full Product Name

Recombinant Human Thrombin, HEK

Product Gene Name

F2 recombinant protein

Product Synonym Names

Thrombin Human, HEK; Thrombin Human Recombinant, HEK; Prothrombin; EC 3.4.21.5; Coagulation factor II; F2; PT; THPH1; RPRGL2; Thrombin, HEK

Host

HEK (HumaXpress)

Form/Format

The Thrombin solution (1mg/ml) contains 20mM MES, pH6.0 and 500mM Choline Chloride.
Sterile Filtered colorless solution.

Preparation and Storage

Store frozen at -20 degree C to -80 degree C for long periods of time. Avoid multiple freeze-thaw cycles.

Molecular Weight

70,037 Da

OMIM

176930

3D Structure

ModBase 3D Structure for P00734

Enzyme Assay

Thrombin (1nM) was assayed using FPRpNA as a substrate (20uM) in 5mM Tris-HCl (pH8.0), 0.1% PEG, 200mM NaCl at 25 degree C and monitored at 405 nm.

Product Categories/Family for F2 recombinant protein

Recombinant & Natural Proteins; Natural Proteins; Thrombin

Other Notes

Small volumes of F2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for F2 purchase

MBS145589 is a recombinant protein targeting F2. Also known as Recombinant Human Thrombin, HEK. Host: HEK (HumaXpress).

Additional Details

NCBI/Uniprot data below describe general gene information for F2. It may not necessarily be applicable to this product.

NCBI GI #

4503635

NCBI GeneID

2147

NCBI Accession #

NP_000497.1

UniProt Primary Accession #

P00734

UniProt Secondary Accession #

Q4QZ40; Q53H04; Q53H06; Q69EZ7; Q7Z7P3; Q9UCA1; B2R7F7; B4E1A7

UniProt Related Accession #

P00734

GenBank Nucleotide #

NM_000506.3

NCBI Official Full Name

prothrombin preproprotein

NCBI Official Synonym Full Names

coagulation factor II (thrombin)

NCBI Official Symbol

NCBI Official Synonym Symbols

PT; THPH1; RPRGL2

UniProt Protein Name

Prothrombin

UniProt Synonym Protein Names

Coagulation factor IICleaved into the following 4 chains:Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain

Protein Family

I-Kappa-B like protein

UniProt Gene Name

UniProt Entry Name

THRB_HUMAN

NCBI Protein Information

prothrombin; prepro-coagulation factor II; prothrombin B-chain; serine protease

UniProt Comments for F2

Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with F2 recombinant protein

Reference Product	PubMed Publications
SERPINC1 recombinant protein	>22 publications with F2 and SERPINC1
FGG recombinant protein	>9 publications with F2 and FGG
FGA recombinant protein	>9 publications with F2 and FGA
FGB recombinant protein	>8 publications with F2 and FGB
F2R recombinant protein	>6 publications with F2 and F2R
GP1BA recombinant protein	>6 publications with F2 and GP1BA
THBD recombinant protein	>2 publications with F2 and THBD

Pathways associated with F2 recombinant protein

Products by Pathway	Pathway Diagram
Angiopoietin Receptor Tie2-mediated Signaling Pathway antibodies	Angiopoietin Receptor Tie2-mediated Signaling Pathway Diagram
Blood Clotting Cascade Pathway antibodies	Blood Clotting Cascade Pathway Diagram
Cell Surface Interactions At The Vascular Wall Pathway antibodies	Cell Surface Interactions At The Vascular Wall Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
Common Pathway antibodies	Common Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies	Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram

Diseases associated with F2 recombinant protein

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>1119 publications with F2 and Nervous System Diseases
Liver Diseases Antibodies	>854 publications with F2 and Liver Diseases
Fibrosis Antibodies	>783 publications with F2 and Fibrosis
Hypertension Antibodies	>694 publications with F2 and Hypertension
Inflammation Antibodies	>613 publications with F2 and Inflammation
Liver Cirrhosis Antibodies	>590 publications with F2 and Liver Cirrhosis
Brain Diseases Antibodies	>496 publications with F2 and Brain Diseases
Heart Diseases Antibodies	>317 publications with F2 and Heart Diseases
Kidney Diseases Antibodies	>276 publications with F2 and Kidney Diseases
Obesity Antibodies	>267 publications with F2 and Obesity

Organs/Tissues associated with F2 recombinant protein

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>1508 publications with F2 and Liver
Uterus Antibodies	>963 publications with F2 and Uterus
Kidney Antibodies	>757 publications with F2 and Kidney
Heart Antibodies	>717 publications with F2 and Heart
Embryonic Tissue Antibodies	>375 publications with F2 and Embryonic Tissue
Connective Tissue Antibodies	>275 publications with F2 and Connective Tissue
Spleen Antibodies	>241 publications with F2 and Spleen
Bone Marrow Antibodies	>109 publications with F2 and Bone Marrow
Mammary Gland Antibodies	>33 publications with F2 and Mammary Gland
Uncharacterized Tissue Antibodies	>2 publications with F2 and Uncharacterized Tissue