Human AP1AR Recombinant Protein – Cat# MBS145704

Adaptor-Related Protein Complex 1 Associated Regulatory Protein (AP1AR) Human Recombinant Protein

Name: AP1AR Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS145704
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS145704

Description: AP1AR Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 322 amino acids (1-302) and having a molecular mass of 36.4 kDa.AP1AR is fused to a 20 amino acid His-tag at N-terminus & purified by… More details

$250 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Adaptor-Related Protein Complex 1 Associated Regulatory Protein (AP1AR), Recombinant Protein

Full Product Name

Recombinant Human Adaptor-Related Protein Complex 1 Associated Regulatory Protein

Product Gene Name

AP1AR recombinant protein

Product Synonym Names

AP1AR Human; Adaptor-Related Protein Complex 1 Associated Regulatory Protein Human Recombinant; AP-1 complex-associated regulatory protein; 2c18; Adapter-related protein complex 1-associated regulatory protein; Gamma-1-adaptin brefeldin A resistance protein; GBAR; Gamma-BAR; Gamma-A1-adaptin and kinesin interactor; Gadkin; AP1AR; C4orf16; PRO0971

Sequence

MGSSHHH HHH SSGLVPRGSH MGNCCWTQCF GLLRKEAGRL QRVGGGGGSK YFRTCSRGEH LTIEFENLVE SDEGESPGSS HRPLTEEEIV DLRERHYDSI AEKQKDLDKK IQKELALQEE KLRLEEEALY AAQREAARAA KQRKLLEQER QRIVQQYHPS NNGEYQSSGP EDDFESCLRN MKSQYEVFRS SRLSSDATVL TPNTESSCDL MTKTKSTSGN DDSTSLDLEW EDEEGMNRML PMRERSKTEE DILRAALKYS NKKTGSNPTS ASDDSNGLEW ENDFVSAEMD DNGNSEYSGF VNPVLELSDS GIRHSDTDQQ TR.

Host

E Coli

Form/Format

The AP1AR solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT.
Sterile Filtered colorless solution.

Purity/Purification

Greater than 90.0% as determined by SDS-PAGE.

Preparation and Storage

Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

Molecular Weight

30,459 Da

OMIM

610851

3D Structure

ModBase 3D Structure for Q63HQ0

Product Categories/Family for AP1AR recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins

Other Notes

Small volumes of AP1AR recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AP1AR purchase

MBS145704 is a recombinant protein targeting AP1AR. Also known as Recombinant Human Adaptor-Related Protein Complex 1 Associated Regulatory Protein. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for AP1AR. It may not necessarily be applicable to this product.

NCBI GI #

190358501

NCBI GeneID

55435

NCBI Accession #

NP_001121898.1

UniProt Primary Accession #

Q63HQ0

UniProt Secondary Accession #

Q96GG6; Q9H0V0; Q9P1L4; B2RCV7

UniProt Related Accession #

Q63HQ0

GenBank Nucleotide #

NM_001128426.1

NCBI Official Full Name

AP-1 complex-associated regulatory protein isoform b

NCBI Official Synonym Full Names

adaptor-related protein complex 1 associated regulatory protein

NCBI Official Symbol

AP1AR

NCBI Official Synonym Symbols

2C18; GBAR; C4orf16; PRO0971; gamma-BAR

UniProt Protein Name

AP-1 complex-associated regulatory protein

UniProt Synonym Protein Names

2c18; Adaptor-related protein complex 1-associated regulatory protein; Gamma-1-adaptin brefeldin A resistance protein; GBAR; Gamma-BAR; Gamma-A1-adaptin and kinesin interactor; Gadkin

Protein Family

AP-1 complex-associated regulatory protein

UniProt Gene Name

AP1AR

UniProt Synonym Gene Names

C4orf16; GBAR; Gamma-BAR; Gadkin

UniProt Entry Name

AP1AR_HUMAN

NCBI Protein Information

AP-1 complex-associated regulatory protein; adapter-related protein complex 1-associated regulatory protein; adaptor-related protein complex 1-associated regulatory protein; gadkin; gamma-1-adaptin brefeldin A resistance protein; gamma-A1-adaptin and kinesin interactor; gamma1-adaptin brefeldin A resistance protein, gamma-BAR

UniProt Comments for AP1AR

AP1AR: Necessary for AP-1 dependent transport between the trans-Golgi network and endosomes. Regulates the membrane association of AP1G1/Gamma1-adaptin, one of the subunits of the AP-1 adapter complex. The direct interaction with AP1G1/Gamma1- adaptin attenuates the release of the AP-1 complex from membranes. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 4q25

Cellular Component: Golgi apparatus; transport vesicle; late endosome; early endosome

Molecular Function: kinesin binding

Biological Process: protein transport; negative regulation of receptor recycling; vesicle targeting, trans-Golgi to endosome

Research Articles on AP1AR

1. conclude that a specific fraction of the AP2-derived endocytic pathway is dedicated to secretory purposes under the control of AP1 and Gadkin

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.