Human STK17B Recombinant Protein – Cat# MBS145709

Serine/Threonine Kinase 17b (STK17B) Human Recombinant Protein

Name: STK17B Recombinant Protein; Serine/Threonine Kinase 17b; Human; MyBioSource
Brand: MyBioSource
SKU: MBS145709
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS145709

Description: STK17B Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 395 amino acids (1-372 a.a) and having a molecular mass of 44.7kDa.STK17B is fused to a 23 amino acid His-tag at N-terminus & purified by… More details

$250 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Serine/Threonine Kinase 17B (STK17B), Recombinant Protein

Full Product Name

Recombinant Human Serine/Threonine Kinase 17B

Product Gene Name

STK17B recombinant protein

Product Synonym Names

STK17B Human; Serine/Threonine Kinase 17B Human Recombinant; Serine/threonine-protein kinase 17B; EC 2.7.11.1; DAP kinase-related apoptosis-inducing protein kinase 2; STK17B; DRAK2

Sequence

MGSSHHH HHH SSGLVPRGSH MGSMSR RRFD CRSISGLLTT TPQIPIKMEN FNNFYILTSK ELGRGKFAVV RQCISKSTGQ EYAAKFLKKR RRGQDCRAEI LHEIAVLELA KSCPRVINLH EVYENTSEII LILEYAAGGE IFSLCLPELA EMVSENDVIR LIKQILEGVY YLHQNNIVHL DLKPQNILLS SIYPLGDIKI VDFGMSRKIG HACELREIMG TPEYLAPEIL NYDPITTATD MWNIGIIAYM LLTHTSPFVG EDNQETYLNI SQVNVDYSEE TFSSVSQLAT DFIQSLLVKN PEKRPTAEIC LSHSWLQQWD FENLFHPEET SSSSQTQDHS VRSSEDKTSK SSCNGTCGDR EDKENIPEDS SMVSKRFRFD DSLPNPHELV SDLLC.

Host

E Coli

Form/Format

STK17B protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl, 10% glycerol and 2mM DTT.
Sterile filtered colorless solution.

Purity/Purification

Greater than 90.0% as determined by SDS-PAGE.

Molecular Weight

42,344 Da

OMIM

604727

3D Structure

ModBase 3D Structure for O94768

Product Categories/Family for STK17B recombinant protein

Protein Kinases; Enzymes; Protein Kinases

Other Notes

Small volumes of STK17B recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for STK17B purchase

MBS145709 is a recombinant protein targeting STK17B. Also known as Recombinant Human Serine/Threonine Kinase 17B. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for STK17B. It may not necessarily be applicable to this product.

NCBI GI #

4758194

NCBI GeneID

9262

NCBI Accession #

NP_004217.1

UniProt Primary Accession #

O94768

UniProt Related Accession #

O94768

GenBank Nucleotide #

NM_004226.3

NCBI Official Full Name

serine/threonine-protein kinase 17B

NCBI Official Synonym Full Names

serine/threonine kinase 17b

NCBI Official Symbol

STK17B

NCBI Official Synonym Symbols

DRAK2

UniProt Protein Name

Serine/threonine-protein kinase 17B

UniProt Synonym Protein Names

DAP kinase-related apoptosis-inducing protein kinase 2

Protein Family

Serine/threonine-protein kinase

UniProt Gene Name

STK17B

UniProt Synonym Gene Names

DRAK2

UniProt Entry Name

ST17B_HUMAN

NCBI Protein Information

serine/threonine-protein kinase 17B; DAP kinase-related apoptosis-inducing protein kinase 2; death-associated protein kinase-related 2

UniProt Comments for STK17B

DRAK2: a calmodulin-dependent kinase of the DAPK family. Interacts with and is regulated by calcineurin homologous protein (CHP), an EF-hand Ca(2+)-binding protein. In vitro, CHP inhibits the apoptosis-inducing protein kinase DRAK2 in the presence of elevated Ca(2+) levels. Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney.

Protein type: Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Protein kinase, CAMK; EC 2.7.11.1; CAMK group; DAPK family

Chromosomal Location of Human Ortholog: 2q32.3

Cellular Component: ER-Golgi intermediate compartment; plasma membrane; nucleus; actin cytoskeleton

Molecular Function: protein serine/threonine kinase activity; ATP binding; protein kinase activity

Biological Process: apoptosis; protein amino acid autophosphorylation; protein amino acid phosphorylation

Research Articles on STK17B

1. A significant interaction between variants in STK17B and PAX8, in papillary thyroid cancer susceptibility, is reported.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with STK17B recombinant protein

Reference Product	PubMed Publications
CHP recombinant protein	>2 publications with STK17B and CHP
SP140L recombinant protein	>1 publications with STK17B and SP140L

Diseases associated with STK17B recombinant protein

Disease Name	Pubmed Publications
Carcinoma Antibodies	>4 publications with STK17B and Carcinoma
Breast Neoplasms Antibodies	>2 publications with STK17B and Breast Neoplasms
Adenocarcinoma Antibodies	>2 publications with STK17B and Adenocarcinoma
Liver Diseases Antibodies	>1 publications with STK17B and Liver Diseases
Cell Transformation, Neoplastic Antibodies	>1 publications with STK17B and Cell Transformation, Neoplastic
Fibrosis Antibodies	>1 publications with STK17B and Fibrosis
Lung Neoplasms Antibodies	>1 publications with STK17B and Lung Neoplasms
Hyperplasia Antibodies	>1 publications with STK17B and Hyperplasia
Carcinoma, Hepatocellular Antibodies	>1 publications with STK17B and Carcinoma, Hepatocellular
Infertility, Male Antibodies	>1 publications with STK17B and Infertility, Male

Organs/Tissues associated with STK17B recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>3 publications with STK17B and Blood
Brain Antibodies	>3 publications with STK17B and Brain
Spleen Antibodies	>2 publications with STK17B and Spleen
Bone Antibodies	>2 publications with STK17B and Bone
Bone Marrow Antibodies	>1 publications with STK17B and Bone Marrow
Thymus Antibodies	>1 publications with STK17B and Thymus
Lung Antibodies	>1 publications with STK17B and Lung
Intestine Antibodies	>1 publications with STK17B and Intestine
Skin Antibodies	>1 publications with STK17B and Skin
Kidney Antibodies	>1 publications with STK17B and Kidney