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L Antigen Family Member 3 (LAGE3) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS145732

Description: LAGE3 Human Recombinant produced in E Coli is a single polypeptide chain containing 166 amino acids (1-143) and having a molecular mass of 17.2kDa. LAGE3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic… More details

$250 / 0.002 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
L Antigen Family Member 3 (LAGE3), Recombinant Protein
Full Product Name
Recombinant Human L Antigen Family Member 3
Product Gene Name
Product Synonym Names
LAGE3 Human; L Antigen Family Member 3 Human Recombinant; CVG5; DXS9879E; DXS9951E; ESO3; ITBA2; EKC/KEOPS complex subunit LAGE3; L antigen family member 3; Protein ESO-3
Sequence
MGSSHHH HHH SSGLVPRGSH MGSMRD ADAD AGGGADGGDG RGGHSCRGGV DTAAAPAGGA PPAHAPGPGR DAASAARGSR MRPHIFTLSV PFPTPLEAEI AHGSLAPDAE PHQRVVGKDL TVSGRILVVR WKAEDCRLLR ISVINFLDQL SLVVRTMQRF GPPVSR
Host
E Coli
Form/Format
The LAGE3 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 50% glycerol and 2mM DTT.
Sterile Filtered colorless solution.
Purity/Purification
Greater than 85% as determined by SDS-PAGE.
Molecular Weight
14,804 Da
OMIM
300060
3D Structure
ModBase 3D Structure for Q14657

Other Notes

Small volumes of LAGE3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LAGE3 purchase

MBS145732 is a recombinant protein targeting LAGE3. Also known as Recombinant Human L Antigen Family Member 3. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for LAGE3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
EKC/KEOPS complex subunit LAGE3
NCBI Official Synonym Full Names
L antigen family, member 3
NCBI Official Symbol
LAGE3
NCBI Official Synonym Symbols
CVG5; ESO3; ITBA2; DXS9879E; DXS9951E
UniProt Protein Name
EKC/KEOPS complex subunit LAGE3
UniProt Synonym Protein Names
L antigen family member 3; Protein ESO-3; Protein ITBA2
Protein Family
UniProt Gene Name
LAGE3
UniProt Synonym Gene Names
DXS9879E; ESO3; ITBA2
UniProt Entry Name
LAGE3_HUMAN
NCBI Protein Information
EKC/KEOPS complex subunit LAGE3; protein ESO-3

NCBI Summary for LAGE3

This gene belongs to the ESO/LAGE gene family, members of which are clustered together on chromosome Xq28, and have similar exon-intron structures. Unlike the other family members which are normally expressed only in testis and activated in a wide range of human tumors, this gene is ubiquitously expressed in somatic tissues. The latter, combined with the finding that it is highly conserved in mouse and rat, suggests that the encoded protein is functionally important. An intronless pseudogene with high sequence similarity to this gene is located on chromosome 9. [provided by RefSeq, Jul 2008]
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UniProt Comments for LAGE3

LAGE3: a member of the ESO/LAGE gene family, members of which are clustered together on chromosome Xq28, and have similar exon-intron structures. Unlike the other family members which are normally expressed only in testis and activated in a wide range of human tumors, this gene is ubiquitously expressed in somatic tissues. The latter, combined with the finding that it is highly conserved in mouse and rat, suggests that the encoded protein is functionally important. An intronless pseudogene with high sequence similarity to this gene is located on chromosome 9. [provided by RefSeq, Jul 2008]

Chromosomal Location of Human Ortholog: Xq28

Cellular Component: nucleus

Biological Process: tRNA processing
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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