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Methionyl Aminopeptidase 1d (METAP1D) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS145748

Description: METAP1D Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 339 amino acids (20-335a.a) and having a molecular mass of 37.4kDa. METAP1D is fused to a 23 amino acid His-tag at N-terminus & purified by… More details

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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Methionyl Aminopeptidase 1D (METAP1D), Recombinant Protein
Full Product Name
Recombinant Human Methionyl Aminopeptidase 1D
Product Synonym Names
METAP1D Human; Methionyl Aminopeptidase 1D Human Recombinant; MAP1D; Metap1l; Methionine aminopeptidase 1D; mitochondrial; MAP 1D; MetAP 1D; Methionyl aminopeptidase type 1D; mitochondrial; Peptidase M 1D; METAP1D
Sequence
MGSSHHH HHH SSGLVPRGSH MGSSSP LNHI YLHKQSSSQQ RRNFFFRRQR DISHSIVLPA AVSSAHPVPK HIKKPDYVTT GIVPDWGDSI EVKNEDQIQG LHQACQLARH VLLLAGKSLK VDMTTEEIDA LVHREIISHN AYPSPLGYGG FPKSVCTSVN NVLCHGIPDS RPLQDGDIIN IDVTVYYNGY HGDTSETFLV GNVDECGKKL VEVARRCRDE AIAACRAGAP FSVIGNTISH ITHQNGFQVC PHFVGHGIGS YFHGHPEIWH HANDSDLPME EGMAFTIEPI ITEGSPEFKV LEDAWTVVSL DNQRSAQFEH TVLITSRGAQ ILTKLPHEA
Host
E Coli
Form/Format
The METAP1D solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl, 20% glycerol and 1mM DTT.
Sterile Filtered clear solution.
Purity/Purification
Greater than 85% as determined by SDS-PAGE.
Molecular Weight
37,088 Da
OMIM
610267
3D Structure
ModBase 3D Structure for Q6UB28

Product Categories/Family for METAP1D recombinant protein

Other Notes

Small volumes of METAP1D recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for METAP1D purchase

MBS145748 is a recombinant protein targeting METAP1D. Also known as Recombinant Human Methionyl Aminopeptidase 1D. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for METAP1D. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
methionine aminopeptidase 1D, mitochondrial
NCBI Official Synonym Full Names
methionyl aminopeptidase type 1D (mitochondrial)
NCBI Official Symbol
METAP1D
NCBI Official Synonym Symbols
MAP1D; MAP 1D; Metap1l; MetAP 1D
UniProt Protein Name
Methionine aminopeptidase 1D, mitochondrial
UniProt Synonym Protein Names
Methionyl aminopeptidase type 1D, mitochondrialPeptidase M 1D
UniProt Gene Name
METAP1D
UniProt Entry Name
MAP12_HUMAN
NCBI Protein Information
methionine aminopeptidase 1D, mitochondrial; CDS of metAP-3 within PCR fragment; MAP 1D; metAP 1D; methionyl aminopeptidase type 1D, mitochondrial; peptidase M 1D

NCBI Summary for METAP1D

The N-terminal methionine excision pathway is an essential process in which the N-terminal methionine is removed from many proteins, thus facilitating subsequent protein modification. In mitochondria, enzymes that catalyze this reaction are celled methionine aminopeptidases (MetAps, or MAPs; EC 3.4.11.18) (Serero et al., 2003 [PubMed 14532271]).[supplied by OMIM, Mar 2008]
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UniProt Comments for METAP1D

MAP1D: Removes the N-terminal methionine from nascent proteins. May play a role in colon tumorigenesis. Belongs to the peptidase M24A family.

Protein type: EC 3.4.11.18; Protease; Mitochondrial

Chromosomal Location of Human Ortholog: 2q31.1

Cellular Component: mitochondrion

Molecular Function: metalloexopeptidase activity; metal ion binding; aminopeptidase activity

Biological Process: peptidyl-methionine modification; proteolysis; N-terminal protein amino acid modification
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with METAP1D recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >1 publications with METAP1D and Brain
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