Human COX5A Recombinant Protein – Cat# MBS145758

Cytochrome C Oxidase Subunit Va (COX5A) Human Recombinant Protein

Name: COX5A Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS145758
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS145758

Description: COX5A Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 132 amino acids (42-150 a.a) and having a molecular mass of 14.9kDa.COX5A is fused to a 23 amino acid His-tag at N-terminus & purified by… More details

$250 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Cytochrome C Oxidase Subunit Va (COX5A), Recombinant Protein

Full Product Name

Recombinant Human Cytochrome C Oxidase Subunit Va

Product Gene Name

COX5A recombinant protein

Product Synonym Names

COX5A Human; Cytochrome C Oxidase Subunit Va Human Recombinant; Cytochrome c oxidase subunit 5A; mitochondrial; Cytochrome c oxidase polypeptide Va; COX5A; VA; COX; COX-VA

Sequence

MGSSHHH HHH SSGLVPRGSH MGSSHG SQET DEEFDARWVT YFNKPDIDAW ELRKGINTLV TYDMVPEPKI IDAALRACRR LNDFASTVRI LEVVKDKAGP HKEIYPYVIQ ELRPTLNELG ISTPEELGLD KV.

Host

E Coli

Form/Format

COX5A protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl, 10% glycerol and 2mM DTT.
Sterile Filtered colorless solution.

Purity/Purification

Greater than 95.0% as determined by SDS-PAGE.

Preparation and Storage

Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

Molecular Weight

16,762 Da

OMIM

603773

3D Structure

ModBase 3D Structure for P20674

Product Categories/Family for COX5A recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins

Other Notes

Small volumes of COX5A recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for COX5A purchase

MBS145758 is a recombinant protein targeting COX5A. Also known as Recombinant Human Cytochrome C Oxidase Subunit Va. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for COX5A. It may not necessarily be applicable to this product.

NCBI GI #

190885499

NCBI GeneID

9377

NCBI Accession #

NP_004246.2

UniProt Primary Accession #

P20674

UniProt Secondary Accession #

P30045; Q8TB65

UniProt Related Accession #

P20674

GenBank Nucleotide #

NM_004255.3

NCBI Official Full Name

cytochrome c oxidase subunit 5A, mitochondrial

NCBI Official Synonym Full Names

cytochrome c oxidase subunit Va

NCBI Official Symbol

COX5A

NCBI Official Synonym Symbols

VA; COX; COX-VA

UniProt Protein Name

Cytochrome c oxidase subunit 5A, mitochondrial

UniProt Synonym Protein Names

Cytochrome c oxidase polypeptide Va

Protein Family

Cytochrome c oxidase

UniProt Gene Name

COX5A

UniProt Entry Name

COX5A_HUMAN

NCBI Protein Information

cytochrome c oxidase subunit 5A, mitochondrial; cytochrome c oxidase polypeptide Va; cytochrome c oxidase polypeptide, mitochondrial; mitochondrial cytochrome c oxidase subunit Va

NCBI Summary for COX5A

Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer of proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit Va of the human mitochondrial respiratory chain enzyme. A pseudogene COX5AP1 has been found in chromosome 14q22. [provided by RefSeq, Jul 2008]

UniProt Comments for COX5A

COX5A: This is the heme A-containing chain of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. Belongs to the cytochrome c oxidase subunit 5A family.

Protein type: Energy Metabolism - oxidative phosphorylation; EC 1.9.3.1; Oxidoreductase; Mitochondrial

Chromosomal Location of Human Ortholog: 15q24.1

Cellular Component: mitochondrial inner membrane

Molecular Function: cytochrome-c oxidase activity; electron carrier activity; metal ion binding

Biological Process: cellular metabolic process; transmembrane transport

Research Articles on COX5A

1. Our current study showed that COX Va may play a role in migration and invasion of NSCLC cells and can be used as a biomarker to predict aggressiveness of NSCLC.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with COX5A recombinant protein

Reference Product	PubMed Publications
COX5B recombinant protein	>22 publications with COX5A and COX5B
COX7C recombinant protein	>4 publications with COX5A and COX7C
CYC1 recombinant protein	>4 publications with COX5A and CYC1
COX4I1 recombinant protein	>2 publications with COX5A and COX4I1
UQCRC1 recombinant protein	>1 publications with COX5A and UQCRC1
MT-CO2 recombinant protein	>1 publications with COX5A and MT-CO2

Pathways associated with COX5A recombinant protein

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Cardiac Muscle Contraction Pathway antibodies	Cardiac Muscle Contraction Pathway Diagram
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Cytochrome C Oxidase Pathway antibodies	Cytochrome C Oxidase Pathway Diagram
Cytochrome C Oxidase Pathway antibodies	Cytochrome C Oxidase Pathway Diagram
Electron Transport Chain Pathway antibodies	Electron Transport Chain Pathway Diagram
Huntington's Disease Pathway antibodies	Huntington's Disease Pathway Diagram
Huntington's Disease Pathway antibodies	Huntington's Disease Pathway Diagram

Diseases associated with COX5A recombinant protein

Disease Name	Pubmed Publications
Mitochondrial Diseases Antibodies	>4 publications with COX5A and Mitochondrial Diseases
Lung Neoplasms Antibodies	>1 publications with COX5A and Lung Neoplasms
Liver Diseases Antibodies	>1 publications with COX5A and Liver Diseases
Breast Neoplasms Antibodies	>1 publications with COX5A and Breast Neoplasms
Disease Models, Animal Antibodies	>1 publications with COX5A and Disease Models, Animal
Heart Diseases Antibodies	>1 publications with COX5A and Heart Diseases
Cardiovascular Diseases Antibodies	>1 publications with COX5A and Cardiovascular Diseases
Inflammation Antibodies	>1 publications with COX5A and Inflammation
Kidney Diseases Antibodies	>1 publications with COX5A and Kidney Diseases
Vascular Diseases Antibodies	>1 publications with COX5A and Vascular Diseases

Organs/Tissues associated with COX5A recombinant protein

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>12 publications with COX5A and Muscle
Brain Antibodies	>9 publications with COX5A and Brain
Heart Antibodies	>4 publications with COX5A and Heart
Kidney Antibodies	>3 publications with COX5A and Kidney
Liver Antibodies	>3 publications with COX5A and Liver
Blood Antibodies	>3 publications with COX5A and Blood
Stomach Antibodies	>1 publications with COX5A and Stomach
Lymph Node Antibodies	>1 publications with COX5A and Lymph Node
Lung Antibodies	>1 publications with COX5A and Lung
Pancreas Antibodies	>1 publications with COX5A and Pancreas