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Processing of Precursor 4 (POP4) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS145777

Description: POP4 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 243 amino acids (1-220 a.a.) and having a molecular mass of 27.8kDa.POP4 is fused to a 23 amino acid His-tag at N-terminus & purified by… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Processing Of Precursor 4 (POP4), Recombinant Protein
Full Product Name
Recombinant Human Processing Of Precursor 4
Product Gene Name
Product Synonym Names
POP4 Human; Processing Of Precursor 4 Human Recombinant; RPP29; Ribonuclease P protein subunit p29; hPOP4
Sequence
MGSSHHH HHH SSGLVPRGSH MGSMKS VIYH ALSQKEANDS DVQPSGAQRA EAFVRAFLKR STPRMSPQAR EDQLQRKAVV LEYFTRHKRK EKKKKAKGLS ARQRRELRLF DIKPEQQRYS LFLPLHELWK QYIRDLCSGL KPDTQPQMIQ AKLLKADLHG AIISVTKSKC PSYVGITGIL LQETKHIFKI ITKEDRLKVI PKLNCVFTVE TDGFISYIYG SKFQLRSSER SAKKFKAKGT IDL
Host
E Coli
Form/Format
POP4 protein solution (1mg/ml) contains 20mM Tris-HCl buffer, (pH 8.0), 0.4M UREA  and 10% glycerol.
Sterile Filtered clear solution.
Purity/Purification
Greater than 85.0% as determined by SDS-PAGE.
Molecular Weight
25,425 Da
OMIM
606114
3D Structure
ModBase 3D Structure for O95707

Other Notes

Small volumes of POP4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for POP4 purchase

MBS145777 is a recombinant protein targeting POP4. Also known as Recombinant Human Processing Of Precursor 4. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for POP4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ribonuclease P protein subunit p29
NCBI Official Synonym Full Names
processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)
NCBI Official Symbol
POP4
NCBI Official Synonym Symbols
RPP29
UniProt Protein Name
Ribonuclease P protein subunit p29
UniProt Gene Name
POP4
UniProt Synonym Gene Names
RPP29; hPOP4
UniProt Entry Name
RPP29_HUMAN
NCBI Protein Information
ribonuclease P protein subunit p29; hPOP4

NCBI Summary for POP4

This gene encodes one of the protein subunits of the small nucleolar ribonucleoprotein complexes: the endoribonuclease for mitochondrial RNA processing complex and the ribonuclease P complex. The encoded protein is localized to the nucleus and associates directly with the RNA component of these complexes. This protein is involved in processing of precursor RNAs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]
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UniProt Comments for POP4

POP4: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. May function with RPP38 to coordinate the nucleolar targeting and/or assembly of RNase P. Belongs to the eukaryotic/archaeal RNase P protein component 1 family.

Protein type: Ribonuclease; RNA-binding; RNA processing; Nucleolus; EC 3.1.26.5

Chromosomal Location of Human Ortholog: 19q12

Cellular Component: nucleolar ribonuclease P complex; ribonuclease MRP complex; ribonuclease P complex

Molecular Function: protein binding; RNA binding; ribonuclease MRP activity; ribonuclease P activity; ribonuclease P RNA binding

Biological Process: tRNA processing; rRNA processing; mRNA cleavage
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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