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Ribosomal Protein S12 (RPS12) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS145824

Description: 800x600 RPS12 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 155 amino acids (1-132 a.a.) and having a molecular mass of 16.9kDa.RPS12 is fused to a 23 amino acid His-tag at N-terminus & purified… More details

$250 / 0.005 mg +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
Ribosomal Protein S12 (RPS12), Recombinant Protein
Full Product Name
Recombinant Human Ribosomal Protein S12
Product Gene Name
RPS12 recombinant protein
Product Synonym Names
RPS12 Human; Ribosomal Protein S12 Human Recombinant; 800x600 S12; 40S ribosomal protein S12. 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UnhideWhenUsed="false" Name="Colorful Grid Accent 6"/> UnhideWhenUsed="false" QFormat="true" Name="Subtle Emphasis"/> UnhideWhenUsed="false" QFormat="true" Name="Intense Emphasis"/> UnhideWhenUsed="false" QFormat="true" Name="Subtle Reference"/> UnhideWhenUsed="false" QFormat="true" Name="Intense Reference"/> UnhideWhenUsed="false" QFormat="true" Name="Book Title"/> /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Calibri"; "sans-serif"; }
Sequence
MGSSHHH HHH SSGLVPRGSH MGSMAE EGIA AGGVMDVNTA LQEVLKTALI HDGLARGIRE AAKALDKRQA HLCVLASNCD EPMYVKLVEA LCAEHQINLI KVDDNKKLGE WVGLCKIDRE GKPRKVVGCS CVVVKDYGKE SQAKDVIEEY FKCKK
Host
E Coli
Form/Format
800x600 RPS12 protein solution (0.25mg/ml) contains 20mM Tris-HCl buffer, (pH 8.0), 0.15M NaCl, and 30% glycerol. Normal 0 false false false EN-US X-NONE HE MicrosoftInternetExplorer4 DefSemiHidden="true" DefQFormat="false" DefPriority="99" LatentStyleCou
Purity/Purification
Greater than 85% as determined by SDS-PAGE.
Molecular Weight
14,515 Da
OMIM
603660
3D Structure
ModBase 3D Structure for P25398

Product Categories/Family for RPS12 recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins; Ribosomal Protein

Other Notes

Small volumes of RPS12 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RPS12 purchase

MBS145824 is a recombinant protein targeting RPS12. Also known as Recombinant Human Ribosomal Protein S12. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for RPS12. It may not necessarily be applicable to this product.

NCBI GI #
14277700
NCBI GeneID
6206
NCBI Accession #
NP_001007.2
UniProt Primary Accession #
P25398
UniProt Secondary Accession #
Q76M58
UniProt Related Accession #
P25398
GenBank Nucleotide #
NM_001016.3
NCBI Official Full Name
40S ribosomal protein S12
NCBI Official Synonym Full Names
ribosomal protein S12
NCBI Official Symbol
RPS12
NCBI Official Synonym Symbols
S12
UniProt Protein Name
40S ribosomal protein S12
Protein Family
40S ribosomal protein
UniProt Gene Name
RPS12
UniProt Entry Name
RS12_HUMAN
NCBI Protein Information
40S ribosomal protein S12

NCBI Summary for RPS12

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S12E family of ribosomal proteins. It is located in the cytoplasm. Increased expression of this gene in colorectal cancers compared to matched normal colonic mucosa has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
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UniProt Comments for RPS12

RPS12: a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S12E family of ribosomal proteins. It is located in the cytoplasm. Increased expression of this gene in colorectal cancers compared to matched normal colonic mucosa has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

Protein type: Translation

Chromosomal Location of Human Ortholog: 6q23.2

Cellular Component: membrane; cytosol

Molecular Function: structural constituent of ribosome

Biological Process: SRP-dependent cotranslational protein targeting to membrane; cellular protein metabolic process; translational elongation; viral reproduction; translation; mRNA catabolic process, nonsense-mediated decay; translational initiation; viral transcription; gene expression; translational termination; viral infectious cycle
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Research Articles on RPS12

1. Our findings provide the first demonstration that RPS12 plays important roles in regulating the proliferation and migration of gastric cancer cells. S100A4 can mediate the effects of RPS12 as a downstream effector

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with RPS12 recombinant protein

 Reference Product  PubMed Publications
 RPS3 recombinant protein  >10 publications with RPS12 and RPS3
 RPS14 recombinant protein  >6 publications with RPS12 and RPS14
 RPL11 recombinant protein  >2 publications with RPS12 and RPL11
 RPS16 recombinant protein  >2 publications with RPS12 and RPS16
 RPS6 recombinant protein  >2 publications with RPS12 and RPS6
 RPS13 recombinant protein  >2 publications with RPS12 and RPS13
 RPS29 recombinant protein  >2 publications with RPS12 and RPS29
 RPS20 recombinant protein  >1 publications with RPS12 and RPS20
 RPS23 recombinant protein  >1 publications with RPS12 and RPS23

Pathways associated with RPS12 recombinant protein

 Products by Pathway  Pathway Diagram
 Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway antibodies  Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway Diagram
 Cap-dependent Translation Initiation Pathway antibodies  Cap-dependent Translation Initiation Pathway Diagram
 Cytoplasmic Ribosomal Proteins Pathway antibodies  Cytoplasmic Ribosomal Proteins Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Eukaryotic Translation Elongation Pathway antibodies  Eukaryotic Translation Elongation Pathway Diagram
 Eukaryotic Translation Initiation Pathway antibodies  Eukaryotic Translation Initiation Pathway Diagram
 Eukaryotic Translation Termination Pathway antibodies  Eukaryotic Translation Termination Pathway Diagram
 Formation Of A Pool Of Free 40S Subunits Pathway antibodies  Formation Of A Pool Of Free 40S Subunits Pathway Diagram
 Formation Of The Ternary Complex, And Subsequently, The 43S Complex Pathway antibodies  Formation Of The Ternary Complex, And Subsequently, The 43S Complex Pathway Diagram
 GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway antibodies  GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway Diagram

Diseases associated with RPS12 recombinant protein

 Disease Name  Pubmed Publications
 Infertility, Male Antibodies  >2 publications with RPS12 and Infertility, Male
 Kidney Diseases Antibodies  >2 publications with RPS12 and Kidney Diseases
 Death Antibodies  >1 publications with RPS12 and Death
 Liver Neoplasms Antibodies  >1 publications with RPS12 and Liver Neoplasms
 Embryo Loss Antibodies  >1 publications with RPS12 and Embryo Loss
 Neoplasm Metastasis Antibodies  >1 publications with RPS12 and Neoplasm Metastasis
 Carcinoma, Hepatocellular Antibodies  >1 publications with RPS12 and Carcinoma, Hepatocellular

Organs/Tissues associated with RPS12 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >3 publications with RPS12 and Muscle
 Vascular Antibodies  >3 publications with RPS12 and Vascular
 Blood Antibodies  >3 publications with RPS12 and Blood
 Stomach Antibodies  >3 publications with RPS12 and Stomach
 Kidney Antibodies  >2 publications with RPS12 and Kidney
 Liver Antibodies  >2 publications with RPS12 and Liver
 Bone Marrow Antibodies  >1 publications with RPS12 and Bone Marrow
 Lymph Node Antibodies  >1 publications with RPS12 and Lymph Node
 Bone Antibodies  >1 publications with RPS12 and Bone
 Lung Antibodies  >1 publications with RPS12 and Lung
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