Human NABP1 Recombinant Protein – Cat# MBS145827

Nucleic Acid Binding Protein 1 (NABP1) Human Recombinant Protein

Name: NABP1 Recombinant Protein; Nucleic Acid Binding Protein 1; Human; MyBioSource
Brand: MyBioSource
SKU: MBS145827
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS145827

Description: NABP1 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 227 amino acids (1-204 a.a) and having a molecular mass of 24.8kDa.NABP1 is fused to a 23 amino acid His-tag at N-terminus & purified by… More details

$250 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Nucleic Acid Binding Protein 1 (NABP1), Recombinant Protein

Full Product Name

Recombinant Human Nucleic Acid Binding Protein 1

Product Gene Name

NABP1 recombinant protein

Product Synonym Names

NABP1 Human; Nucleic Acid Binding Protein 1 Human Recombinant; Nucleic Acid Binding Protein 1; OBFC2A; Sensor Of Single-Strand DNA Complex Subunit B2; Single-Stranded DNA-Binding Protein 2; SSB2; Oligonucleotide/Oligosaccharide-Binding Fold Containing 2A; Nucleic Acid-Binding Protein 1; Oligonucleotide/Oligosaccharide-Binding Fold-Containing Protein 2A; Sensor Of SsDNA Subunit B2; SOSS-B2; SOSS Complex Subunit B2; hSSB2

Sequence

MGSSHHH HHH SSGLVPRGSH MGSMNR VNDP LIFIRDIKPG LKNLNVVFIV LEIGRVTKTK DGHEVRSCKV ADKTGSITIS VWDEIGGLIQ PGDIIRLTRG YASMWKGCLT LYTGRGGELQ KIGEFCMVYS EVPNFSEPNP DYRGQQNKGA QSEQKNNSMN SNMGTGTFGP VGNGVHTGPE SREHQFSHAG RSNGRGLINP QLQGTASNQT VMTTISNGRD PRRAFKR

Host

E Coli

Form/Format

NABP1 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0) 0.2M, NaCl, 50% glycerol and 2mM DTT.
Sterile Filtered clear solution.

Purity/Purification

Greater than 95.0% as determined by SDS-PAGE.

Molecular Weight

14,677 Da

OMIM

612103

3D Structure

ModBase 3D Structure for Q96AH0

Product Categories/Family for NABP1 recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins

Other Notes

Small volumes of NABP1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NABP1 purchase

MBS145827 is a recombinant protein targeting NABP1. Also known as Recombinant Human Nucleic Acid Binding Protein 1. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for NABP1. It may not necessarily be applicable to this product.

NCBI GI #

72534722

NCBI GeneID

64859

NCBI Accession #

NP_001026886.1

UniProt Primary Accession #

Q96AH0

UniProt Secondary Accession #

Q658Y8; Q9H5X6

UniProt Related Accession #

Q96AH0

GenBank Nucleotide #

NM_001031716.2

NCBI Official Full Name

SOSS complex subunit B2 isoform 1

NCBI Official Synonym Full Names

nucleic acid binding protein 1

NCBI Official Symbol

NABP1

NCBI Official Synonym Symbols

SSB2; OBFC2A; SOSS-B2

UniProt Protein Name

SOSS complex subunit B2

UniProt Synonym Protein Names

Nucleic acid-binding protein 1; Oligonucleotide/oligosaccharide-binding fold-containing protein 2A; Sensor of single-strand DNA complex subunit B2; Sensor of ssDNA subunit B2; SOSS-B2; Single-stranded DNA-binding protein 2; hSSB2

Protein Family

SOSS complex

UniProt Gene Name

NABP1

UniProt Synonym Gene Names

OBFC2A; SSB2; SOSS-B2; hSSB2

UniProt Entry Name

SOSB2_HUMAN

NCBI Protein Information

SOSS complex subunit B2; nucleic acid-binding protein 1; oligonucleotide/oligosaccharide-binding fold containing 2A; oligonucleotide/oligosaccharide-binding fold-containing protein 2A; sensor of single-strand DNA complex subunit B2; sensor of ssDNA subunit B2; single-stranded DNA-binding protein 2

NCBI Summary for NABP1

Single-stranded DNA (ssDNA)-binding proteins, such as OBFC2A, are ubiquitous and essential for a variety of DNA metabolic processes, including replication, recombination, and detection and repair of damage (Richard et al., 2008 [PubMed 18449195]).[supplied by OMIM, Jun 2008]

UniProt Comments for NABP1

OBFC2A: Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways. Belongs to the SOSS-B family. SOSS-B2 subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding; DNA repair, damage; Cell cycle regulation

Chromosomal Location of Human Ortholog: 2q32.3

Cellular Component: nucleoplasm; cytoplasm; nucleus

Molecular Function: RNA binding; single-stranded DNA binding

Biological Process: mitotic cell cycle checkpoint; response to ionizing radiation; DNA repair; response to DNA damage stimulus; double-strand break repair via homologous recombination

Research Articles on NABP1

1. hSSB1 and hSSB2 form two separate complexes with similar structures, and both complexes participate in DNA damage response.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with NABP1 recombinant protein

Reference Product	PubMed Publications
INTS3 recombinant protein	>1 publications with NABP1 and INTS3

Organs/Tissues associated with NABP1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Thyroid Antibodies	>1 publications with NABP1 and Thyroid
Thymus Antibodies	>1 publications with NABP1 and Thymus