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Nuclear Receptor Binding Factor 2 (NRBF2) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS145843

Description: NRBF2 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 266 amino acids (45-287) and having a molecular mass of 29.9 kDa.NRBF2 is fused to a 23 amino acid His-tag at N-terminus & purified by… More details

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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Nuclear Receptor Binding Factor 2 (NRBF2), Recombinant Protein
Full Product Name
Recombinant Human Nuclear Receptor Binding Factor 2
Product Gene Name
Product Synonym Names
NRBF2 Human; Nuclear Receptor Binding Factor 2 Human Recombinant; Nuclear receptor binding factor 2; COPR1; COPR2; NRBF-2; Nuclear receptor-binding factor 2; Comodulator of PPAR and RXR; NRBF2; COPR
Sequence
MGSSHHH HHH SSGLVPRGSH MGSMKL TQSE QAHLSLELQR DSHMKQLLLI QERWKRAQRE ERLKAQQNTD KDAAAHLQTS HKPSAEDAEG QSPLSQKYSP STEKCLPEIQ GIFDRDPDTL LYLLQQKSEP AEPCIGSKAP KDDKTIIEEQ ATKIADLKRH VEFLVAENER LRKENKQLKA EKARLLKGPI EKELDVDADF VETSELWSLP PHAETATASS TWQKFAANTG KAKDIPIPNL PPLDFPSPEL PLMELSEDIL KGFMNN.
Host
E Coli
Form/Format
The NRBF2 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 20% glycerol and 1mM DTT.
Sterile Filtered colorless solution.
Purity/Purification
Greater than 85.0% as determined by SDS-PAGE.
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Molecular Weight
31,001 Da
3D Structure
ModBase 3D Structure for Q96F24

Other Notes

Small volumes of NRBF2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NRBF2 purchase

MBS145843 is a recombinant protein targeting NRBF2. Also known as Recombinant Human Nuclear Receptor Binding Factor 2. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for NRBF2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
nuclear receptor-binding factor 2 isoform 2
NCBI Official Synonym Full Names
nuclear receptor binding factor 2
NCBI Official Symbol
NRBF2
NCBI Official Synonym Symbols
COPR1; COPR2; NRBF-2
UniProt Protein Name
Nuclear receptor-binding factor 2
UniProt Synonym Protein Names
Comodulator of PPAR and RXR
UniProt Gene Name
NRBF2
UniProt Synonym Gene Names
COPR; NRBF-2
UniProt Entry Name
NRBF2_HUMAN
NCBI Protein Information
nuclear receptor-binding factor 2; comodulator of PPAR and RXR 1; comodulator of PPAR and RXR 2; nuclear receptor binding factor-2

UniProt Comments for NRBF2

NRBF2: May modulate transcriptional activation by target nuclear receptors. Can act as transcriptional activator (in vitro). Interacts with PPARA, PPARD and PPARG. Interacts with RARA, RARG and RXRA in the presence of bound ligand. Detected in keratinocytes, liver and placenta. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Nuclear receptor co-regulator; Autophagy; Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 10q21.3

Cellular Component: nucleoplasm; cytoplasm

Biological Process: transcription initiation from RNA polymerase II promoter; regulation of transcription, DNA-dependent; gene expression
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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