Human SLAMF1 Recombinant Protein – Cat# MBS145851

SLAMF1 Human Recombinant Protein

Name: SLAMF1 Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS145851
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS145851

Description: SLAMF1 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 240 amino acids (21-237 a.a) and having a molecular mass of 26.7kDa.SLAMF1 is fused to a 23 amino acid His-tag at N-terminus & purified by… More details

$250 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SLAMF1, Recombinant Protein

Full Product Name

Recombinant Human SLAMF1

Product Gene Name

SLAMF1 recombinant protein

Product Synonym Names

SLAMF1 Human; SLAMF1 Human Recombinant; Signaling lymphocytic activation molecule; CDw150; IPO-3; CD150; SLAMF1; SLAM

Sequence

MGSSHHH HHH SSGLVPRGSH MGSASY GTGG RMMNCPKILR QLGSKVLLPL TYERINKSMN KSIHIVVTMA KSLENSVENK IVSLDPSEAG PPRYLGDRYK FYLENLTLGI RESRKEDEGW YLMTLEKNVS VQRFCLQLRL YEQVSTPEIK VLNKTQENGT CTLILGCTVE KGDHVAYSWS EKAGTHPLNP ANSSHLLSLT LGPQHADNIY ICTVSNPISN NSQTFSPWPG CRTDPSETKP .

Host

E Coli

Form/Format

SLAMF1 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M UREA and 10% glycerol.
Sterile Filtered colorless solution.

Purity/Purification

Greater than 85.0% as determined by SDS-PAGE.

Preparation and Storage

Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

Molecular Weight

33,839 Da

OMIM

603492

3D Structure

ModBase 3D Structure for Q13291

Product Categories/Family for SLAMF1 recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins

Other Notes

Small volumes of SLAMF1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SLAMF1 purchase

MBS145851 is a recombinant protein targeting SLAMF1. Also known as Recombinant Human SLAMF1. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for SLAMF1. It may not necessarily be applicable to this product.

NCBI GI #

4506969

NCBI GeneID

6504

NCBI Accession #

NP_003028.1

UniProt Primary Accession #

Q13291

UniProt Secondary Accession #

Q5W172; Q9HBE8

UniProt Related Accession #

Q13291

GenBank Nucleotide #

NM_003037.3

NCBI Official Full Name

signaling lymphocytic activation molecule

NCBI Official Synonym Full Names

signaling lymphocytic activation molecule family member 1

NCBI Official Symbol

SLAMF1

NCBI Official Synonym Symbols

SLAM; CD150; CDw150

UniProt Protein Name

Signaling lymphocytic activation molecule

UniProt Synonym Protein Names

CDw150; IPO-3; CD_antigen: CD150

Protein Family

Signaling lymphocytic activation molecule

UniProt Gene Name

SLAMF1

UniProt Synonym Gene Names

SLAM

UniProt Entry Name

SLAF1_HUMAN

NCBI Protein Information

signaling lymphocytic activation molecule; IPO-3

UniProt Comments for SLAMF1

SLAM: a type I membrane protein present on the surface of B cells, T cells and CD83+ dendritic cells. A high-affinity self-ligand considered to be important in bidirectional T <-> B-cell stimulation. SLAM-induced signal-transduction events in T lymphocytes are different from those in B cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A (SAP) acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (SHP-2)-dependent signal transduction operates. Its cytoplasmic domain interacts with SAP through part of its SH2 domain, and with SHP-2. Three alternatively spliced isoforms have been described.

Protein type: Receptor, misc.; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q23.3

Cellular Component: integral to membrane; phagocytic vesicle; external side of plasma membrane

Molecular Function: protein binding; transmembrane receptor activity; antigen binding

Biological Process: viral reproduction; regulation of catalytic activity; regulation of vesicle fusion; positive regulation of cell proliferation; lymphocyte activation; signal transduction

Research Articles on SLAMF1

1. Molecular dynamics analysis revealed that mutant R32Q and T53I structures of SAP exhibited structural variation with respect to their backbone atoms before and after binding with the unphosphorylated SLAM peptide.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with SLAMF1 recombinant protein

Reference Product	PubMed Publications
FYN recombinant protein	>4 publications with SLAMF1 and FYN
SH2D1A recombinant protein	>4 publications with SLAMF1 and SH2D1A
UVRAG recombinant protein	>2 publications with SLAMF1 and UVRAG
BECN1 recombinant protein	>2 publications with SLAMF1 and BECN1
PTPRC recombinant protein	>1 publications with SLAMF1 and PTPRC
SH2D1B recombinant protein	>1 publications with SLAMF1 and SH2D1B

Pathways associated with SLAMF1 recombinant protein

Products by Pathway	Pathway Diagram
Measles Pathway antibodies	Measles Pathway Diagram
Measles Pathway antibodies	Measles Pathway Diagram

Diseases associated with SLAMF1 recombinant protein

Disease Name	Pubmed Publications
Inflammation Antibodies	>4 publications with SLAMF1 and Inflammation
Necrosis Antibodies	>4 publications with SLAMF1 and Necrosis
Kidney Diseases Antibodies	>1 publications with SLAMF1 and Kidney Diseases
Disease Models, Animal Antibodies	>1 publications with SLAMF1 and Disease Models, Animal
Fetal Growth Retardation Antibodies	>1 publications with SLAMF1 and Fetal Growth Retardation
Heart Diseases Antibodies	>1 publications with SLAMF1 and Heart Diseases

Organs/Tissues associated with SLAMF1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>23 publications with SLAMF1 and Blood
Thymus Antibodies	>6 publications with SLAMF1 and Thymus
Bone Antibodies	>5 publications with SLAMF1 and Bone
Heart Antibodies	>2 publications with SLAMF1 and Heart
Pharynx Antibodies	>1 publications with SLAMF1 and Pharynx
Muscle Antibodies	>1 publications with SLAMF1 and Muscle
Placenta Antibodies	>1 publications with SLAMF1 and Placenta
Kidney Antibodies	>1 publications with SLAMF1 and Kidney
Lymph Node Antibodies	>1 publications with SLAMF1 and Lymph Node