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Visual System Homeobox 2 (VSX2) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1458751

This gene encodes a homeobox protein originally described as a retina-specific transcription factor. Mutations in this gene are associated with microphthalmia, cataracts and iris abnormalities. More details

$1080 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Visual system homeobox 2 (Vsx2), Recombinant Protein
Full Product Name
Recombinant Mouse Visual system homeobox 2 (Vsx2)
Product Gene Name
Vsx2 recombinant protein
Product Synonym Gene Name
Vsx2
Sequence
MTGKAGEALS KPKSETVAKS TSGGAPARCT GFGIQEILGL NKEPPSSHPR AALDGLAPGH LLAARSVLSP AGVGSMGLLG PGGLPGFYTQ PTFLEVLSDP QSVHLQPLGR ASGPLDTSQT ASSDSEDVSS SDRKMSKSAL NQTKKRKKRR HRTIFTSYQL EELEKAFNEA HYPDVYAREM LAMKTELPED RIQVWFQNRR AKWRKREKCW GRSSVMAEYG LYGAMVRHSI PLPESILKSA KDGIMDSCAP WLLGMHKKSL EAAAESGRKP EVERQALPKL DKMEQEERAP EAQAAISQEE LRENSIAALR AKAQEHSTKV LGTVSGPDSL ARNAEKPEEE DATEEDRPAE KLSPPQLEDM A
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
39,436 Da
Sequence Positions
1-361, full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q61412
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Vsx2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Vsx2 purchase

MBS1458751 is a recombinant protein targeting Vsx2. Also known as Recombinant Mouse Visual system homeobox 2 (Vsx2). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Vsx2. It may not necessarily be applicable to this product.

NCBI GI #
6671750
NCBI GeneID
12677
NCBI Accession #
NP_031727.1
UniProt Primary Accession #
Q61412
UniProt Related Accession #
Q61412
GenBank Nucleotide #
NM_007701.3
NCBI Official Full Name
visual system homeobox 2 isoform 2
NCBI Official Synonym Full Names
visual system homeobox 2
NCBI Official Symbol
Vsx2
NCBI Official Synonym Symbols
or; Chx10; Hox10; Hox-10
UniProt Protein Name
Visual system homeobox 2
UniProt Synonym Protein Names
Ceh-10 homeodomain-containing homolog; Homeobox protein CHX10
Protein Family
Visual system homeobox
UniProt Gene Name
Vsx2
UniProt Synonym Gene Names
Chx10
NCBI Protein Information
visual system homeobox 2

NCBI Summary for Vsx2

This gene encodes a member of the Vsx (visual system homeobox) family which belongs to the larger PRD homeobox class. The encoded protein is required for eye organogenesis and controls retinal development. Disruption of this gene is associated with ocular retardation J (orJ), a mouse disease which causes microphthalmia, retinal degeneration and optic nerve aplasia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]
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UniProt Comments for Vsx2

Plays a significant role in the specification and morphogenesis of the sensory retina. May also participate in the development of the cells of the inner nuclear layer, particularly bipolar cells.

Research Articles on Vsx2

1. Vsx2 represses Mitf in a cell-autonomous way. It also uses cell-nonautonomous mechanisms to regulate progenitor properties in the embryonic retina. Vsx2's role in regulating Mitf is in part separable from its role in promoting proliferation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Vsx2 recombinant protein

 Reference Product  PubMed Publications
 Pax6 recombinant protein  >18 publications with Vsx2 and Pax6

Diseases associated with Vsx2 recombinant protein

 Disease Name  Pubmed Publications
 Eye Abnormalities Antibodies  >22 publications with Vsx2 and Eye Abnormalities
 Disease Models, Animal Antibodies  >4 publications with Vsx2 and Disease Models, Animal
 Abnormalities, Multiple Antibodies  >2 publications with Vsx2 and Abnormalities, Multiple
 MICROPHTHALMIA, ISOLATED 2 Antibodies  >2 publications with Vsx2 and MICROPHTHALMIA, ISOLATED 2
 Stroke Antibodies  >1 publications with Vsx2 and Stroke
 Cerebral Infarction Antibodies  >1 publications with Vsx2 and Cerebral Infarction
 Limb Deformities, Congenital Antibodies  >1 publications with Vsx2 and Limb Deformities, Congenital
 Uterine Neoplasms Antibodies  >1 publications with Vsx2 and Uterine Neoplasms
 Premature Birth Antibodies  >1 publications with Vsx2 and Premature Birth
 Uterine Diseases Antibodies  >1 publications with Vsx2 and Uterine Diseases

Organs/Tissues associated with Vsx2 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >72 publications with Vsx2 and Eye
 Brain Antibodies  >5 publications with Vsx2 and Brain
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