Mouse mLGALS3 Recombinant Protein – Cat# MBS145883

Galectin-3 (mLGALS3) Mouse Recombinant Protein

Name: mLGALS3 Recombinant Protein; Galectin-3; Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS145883
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS145883

Description: LGALS3 Mouse Recombinant produced in E Coli is a single polypeptide chain containing 287 amino acids (1-264) and having a molecular mass of 29.8 kDa. LGALS3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary… More details

$250 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Galectin-3 (mLGALS3), Recombinant Protein

Full Product Name

Recombinant Mouse Galectin-3

Product Gene Name

mLGALS3 recombinant protein

Product Synonym Names

LGALS3 Mouse; Galectin-3 Mouse Recombinant; CBP35; GAL3; GALBP; GALIG; LGALS2; MAC2; Galectin-3; Lectin; galactose binding; soluble 3; Lectin; galactose binding; soluble 3; isoform CRA_a; Lectin; galactose binding; soluble 3; isoform CRA_d; Lgals3

Sequence

MGSSHHH HHH SSGLVPRGSH MGSMAD SFSL NDALAGSGNP NPQGYPGAWG NQPGAGGYPG AAYPGAYPGQ APPGAYPGQA PPGAYPGQAP PSAYPGPTAP GAYPGPTAPG AYPGSTAPGA FPGQPGAPGA YPSAPGGYPA AGPYGVPAGP LTVPYDLPLP GGVMPRMLIT IMGTVKPNAN RIVLDFRRGN DVAFHFNPRF NENNRRVIVC NTKQDNNWGK EERQSAFPFE SGKPFKIQVL VEADHFKVAV NDAHLLQYNH RMKNLREISQ LGISGDITLT SANHAMI

Host

E Coli

Form/Format

The LGALS3 solution (0.5mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 50% glycerol,1mM DTT and 2mM EDTA.
Sterile Filtered colorless solution.

Purity/Purification

Greater than 95% as determined by SDS-PAGE.

Molecular Weight

27,415 Da

3D Structure

ModBase 3D Structure for Q8C253

Product Categories/Family for mLGALS3 recombinant protein

Cytokines and Growth Factors; Growth Factors; Galectin

Other Notes

Small volumes of mLGALS3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for mLGALS3 purchase

MBS145883 is a recombinant protein targeting mLGALS3. Also known as Recombinant Mouse Galectin-3. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for mLGALS3. It may not necessarily be applicable to this product.

NCBI GI #

225543163

NCBI GeneID

16854

NCBI Accession #

NP_001139425.1

UniProt Primary Accession #

Q8C253

UniProt Related Accession #

P16110

GenBank Nucleotide #

NM_001145953.1

NCBI Official Full Name

galectin-3

NCBI Official Synonym Full Names

lectin, galactose binding, soluble 3

NCBI Official Symbol

Lgals3

NCBI Official Synonym Symbols

GBP; L-34; gal3; Mac-2

UniProt Protein Name

Galectin

Protein Family

Galectin-3-binding protein

UniProt Gene Name

Lgals3

UniProt Entry Name

Q8C253_MOUSE

NCBI Protein Information

galectin-3; 35 kDa lectin; CBP 35; L-34 galactoside-binding lectin; carbohydrate-binding protein 35; gal-3; galactose-specific lectin 3; igE-binding protein; laminin-binding protein; lectin L-29; mac-2 antigen

UniProt Comments for mLGALS3

Galectin-3: galactose-specific lectin which binds IgE. Expressed at a high level in the colonic epithelium. Also abundant in activated macrophages.

Protein type: Motility/polarity/chemotaxis; Extracellular matrix; Cell surface

Cellular Component: extracellular matrix; spliceosome; extracellular space; proteinaceous extracellular matrix; cell surface; membrane; cytoplasm; mitochondrial inner membrane; extracellular region; immunological synapse; nucleus; external side of plasma membrane

Molecular Function: monosaccharide binding; protein binding; advanced glycation end-product receptor activity; laminin binding; IgE binding; carbohydrate binding; chemoattractant activity; disaccharide binding

Biological Process: neutrophil chemotaxis; extracellular matrix organization and biogenesis; immune system process; positive regulation of serotonin secretion; negative regulation of endocytosis; RNA splicing; regulation of T cell proliferation; negative regulation of T cell receptor signaling pathway; signal transduction; macrophage chemotaxis; monocyte chemotaxis; positive regulation of angiogenesis; positive chemotaxis; positive regulation of cell proliferation; eosinophil chemotaxis; innate immune response; cell differentiation; mRNA processing; skeletal development; negative regulation of apoptosis

Research Articles on mLGALS3

1. Our results suggested that the elevated expression of gelectin-3 in LLC tumor cells may contribute to the migration of MDSCs to the tumor microenvironment in response to cisplatin.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with mLGALS3 recombinant protein

Products by Pathway	Pathway Diagram
Advanced Glycosylation Endproduct Receptor Signaling Pathway antibodies	Advanced Glycosylation Endproduct Receptor Signaling Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram

Diseases associated with mLGALS3 recombinant protein

Disease Name	Pubmed Publications
Carcinoma Antibodies	>546 publications with mLGALS3 and Carcinoma
Inflammation Antibodies	>279 publications with mLGALS3 and Inflammation
Adenocarcinoma Antibodies	>229 publications with mLGALS3 and Adenocarcinoma
Fibrosis Antibodies	>166 publications with mLGALS3 and Fibrosis
Disease Models, Animal Antibodies	>154 publications with mLGALS3 and Disease Models, Animal
Neoplasm Metastasis Antibodies	>152 publications with mLGALS3 and Neoplasm Metastasis
Heart Diseases Antibodies	>140 publications with mLGALS3 and Heart Diseases
Adenoma Antibodies	>137 publications with mLGALS3 and Adenoma
Brain Diseases Antibodies	>116 publications with mLGALS3 and Brain Diseases
Breast Neoplasms Antibodies	>113 publications with mLGALS3 and Breast Neoplasms

Organs/Tissues associated with mLGALS3 recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>599 publications with mLGALS3 and Blood
Thyroid Antibodies	>297 publications with mLGALS3 and Thyroid
Brain Antibodies	>155 publications with mLGALS3 and Brain
Lung Antibodies	>129 publications with mLGALS3 and Lung
Liver Antibodies	>129 publications with mLGALS3 and Liver
Kidney Antibodies	>127 publications with mLGALS3 and Kidney
Bone Antibodies	>113 publications with mLGALS3 and Bone
Muscle Antibodies	>94 publications with mLGALS3 and Muscle
Skin Antibodies	>89 publications with mLGALS3 and Skin
Bone Marrow Antibodies	>66 publications with mLGALS3 and Bone Marrow