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Nephroblastoma Overexpressed (mNOV) Mouse Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS145911

Description: NOV Mouse Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 333 amino acids and having a molecular mass of 36.4kDa.The NOV is purified by proprietary chromatographic techniques.Introduction: Nephroblastoma… More details

$250 / 0.005 mg +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Nephroblastoma Overexpressed (mNOV), Active Protein
Full Product Name
Recombinant Mouse Nephroblastoma Overexpressed
Product Gene Name
Product Synonym Names
NOV Mouse; Nephroblastoma Overexpressed Mouse Recombinant; Protein NOV homolog; NovH; CCN family member 3; Nephroblastoma-overexpressed gene protein homolog; Nov; Ccn3; C130088N23Rik
Sequence
QVSASLRCPS RCPPKCPSIS PTCAPGVRSV LDGCSCCPVC ARQRGESCSE MRPCDQSSGL YCDRSADPNN QTGICMVPEG DNCVFDGVIY RNGEKFEPNC QYFCTCRDGQ IGCLPRCQLD VLLPGPDCPA PRKVAVPGEC CEKWTCGSDE QGTQGTLGGL ALPAYRPEAT VGVEVSDSSI NCIEQTTEWS ACSKSCGMGV STRVTNRNRQ CEMVKQTRLC IVRPCEQEPE EVTDKKGKKC LRTKKSLKAI HLQFENCTSL YTYKPRFCGV CSDGRCCTPH NTKTIQVEFQ CLPGEIIKKP VMVIGTCTCY SNCPQNNEAF LQDLELKTSR GEI
Host
E Coli
Form/Format
NOV protein was lyophilized from a 0.2 um filtered concentrated solution in 20mM Tris-HCl, pH 8.5 and 150mM NaCl.
Sterile Filtered White lyophilized (freeze-dried) powder.
Purity/Purification
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Preparation and Storage
Lyophilized NOV although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution NOV should be stored at 4 degree C between 2-7 days and for future use below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Molecular Weight
38,928 Da
3D Structure
ModBase 3D Structure for Q64299
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Solubility
It is recommended to reconstitute the lyophilized NOV in sterile 18M-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Biological Activity
The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 1.0 ug/ml, corresponding to a specific activity of > 1000 IU/mg.

Other Notes

Small volumes of mNOV active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for mNOV purchase

MBS145911 is an active protein targeting mNOV. Also known as Recombinant Mouse Nephroblastoma Overexpressed. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for mNOV. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
protein NOV homolog
NCBI Official Synonym Full Names
nephroblastoma overexpressed gene
NCBI Official Symbol
Nov
NCBI Official Synonym Symbols
CCN3; C130088N23Rik
UniProt Protein Name
Protein NOV homolog
UniProt Synonym Protein Names
CCN family member 3; Nephroblastoma-overexpressed gene protein homolog
Protein Family
UniProt Gene Name
Nov
UniProt Synonym Gene Names
Ccn3; NovH
UniProt Entry Name
NOV_MOUSE
NCBI Protein Information
protein NOV homolog; CCN family member 3; nephroblastoma overexpressed gene protein homolog; nephroblastoma-overexpressed gene protein homolog; novH

UniProt Comments for mNOV

NOV: Immediate-early protein likely to play a role in cell growth regulation. Belongs to the CCN family. Expression is down-regulated by WT1. Interacts with FBLN1.

Protein type: Secreted, signal peptide; Secreted

Cellular Component: extracellular matrix; proteinaceous extracellular matrix; intracellular membrane-bound organelle; cell soma; axon; dendrite; extracellular region

Molecular Function: heparin binding; integrin binding; insulin-like growth factor binding; growth factor activity

Biological Process: cell-cell signaling; regulation of gene expression; regulation of cell growth; cell adhesion; signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with mNOV active protein

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