Human SYT4 Recombinant Protein – Cat# MBS145949

Synaptotagmin IV (SYT4) Human Recombinant Protein

Name: SYT4 Recombinant Protein; Synaptotagmin IV; Human; MyBioSource
Brand: MyBioSource
SKU: MBS145949
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS145949

Description: SYT4 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 409 amino acids (38-425a.a) and having a molecular mass of 46.1kDa. SYT4 is fused to a 21 amino acid His-tag at N-terminus & purified by… More details

$250 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Synaptotagmin IV (SYT4), Recombinant Protein

Full Product Name

Recombinant Human Synaptotagmin IV

Product Gene Name

SYT4 recombinant protein

Product Synonym Names

SYT4 Human; Synaptotagmin IV Human Recombinant; HsT1192; KIAA1342; Synaptotagmin-4; Synaptotagmin IV; SytIV; SYT4

Sequence

MGSSHHH HHH SSGLVPRGSH MCQRKS SKSN KTPPYKFVHV LKGVDIYPEN LNSKKKFGAD DKNEVKNKPA VPKNSLHLDL EKRDLNGNFP KTNLKPGSPS DLENATPKLF LEGEKESVSP ESLKSSTSLT SEEKQEKLGT LFFSLEYNFE RKAFVVNIKE ARGLPAMDEQ SMTSDPYIKM TILPEKKHKV KTRVLRKTLD PAFDETFTFY GIPYTQIQEL ALHFTILSFD RFSRDDIIGE VLIPLSGIEL SEGKMLMNRE IIKRNVRKSS GRGELLISLC YQSTTNTLTV VVLKARHLPK SDVSGLSDPY VKVNLYHAKK RISKKKTHVK KCTPNAVFNE LFVFDIPCEG LEDISVEFLV LDSERGSRNE VIGQLVLGAA AEGTGGEHWK EICDYPRRQI AKWHVLCDG

Host

E Coli

Form/Format

SYT4 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl, 20% glycerol and 1mM DTT.
Sterile Filtered colorless solution.

Purity/Purification

Greater than 90% as determined by SDS-PAGE.

Molecular Weight

46,064 Da

OMIM

600103

3D Structure

ModBase 3D Structure for Q9H2B2

Product Categories/Family for SYT4 recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins; Synaptotagmin

Other Notes

Small volumes of SYT4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SYT4 purchase

MBS145949 is a recombinant protein targeting SYT4. Also known as Recombinant Human Synaptotagmin IV. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for SYT4. It may not necessarily be applicable to this product.

NCBI GI #

24308219

NCBI GeneID

6860

NCBI Accession #

NP_065834.1

UniProt Primary Accession #

Q9H2B2

UniProt Secondary Accession #

Q9P2K4; B4DEU3

UniProt Related Accession #

Q9H2B2

GenBank Nucleotide #

NM_020783.3

NCBI Official Full Name

synaptotagmin-4

NCBI Official Synonym Full Names

synaptotagmin IV

NCBI Official Symbol

SYT4

NCBI Official Synonym Symbols

HsT1192

UniProt Protein Name

Synaptotagmin-4

UniProt Synonym Protein Names

Synaptotagmin IV; SytIV

Protein Family

Synaptotagmin

UniProt Gene Name

SYT4

UniProt Synonym Gene Names

KIAA1342; SytIV

UniProt Entry Name

SYT4_HUMAN

NCBI Protein Information

synaptotagmin-4; synaptotagmin 4; sytIV

UniProt Comments for SYT4

SYT4: May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Belongs to the synaptotagmin family.

Protein type: Vesicle; Calcium-binding; Membrane protein, integral

Chromosomal Location of Human Ortholog: 18q12.3

Cellular Component: neuron projection; synaptic vesicle membrane; intracellular membrane-bound organelle; perinuclear region of cytoplasm; integral to membrane; plasma membrane; cell junction

Molecular Function: clathrin binding; SNARE binding; phosphatidylserine binding; transporter activity; calcium ion binding

Biological Process: negative regulation of vesicle fusion; exocytosis; negative regulation of calcium ion-dependent exocytosis; neurotransmitter secretion

Research Articles on SYT4

1. Synaptotagmin 4 negatively regulates oxytocin exocytosis, and dietary obesity is associated with increased synaptotagmin 4 binding to vesicles.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with SYT4 recombinant protein

Reference Product	PubMed Publications
SYT1 recombinant protein	>15 publications with SYT4 and SYT1
STX1A recombinant protein	>2 publications with SYT4 and STX1A
STX3 recombinant protein	>1 publications with SYT4 and STX3

Diseases associated with SYT4 recombinant protein

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>11 publications with SYT4 and Nervous System Diseases
Seizures Antibodies	>5 publications with SYT4 and Seizures
Disease Models, Animal Antibodies	>4 publications with SYT4 and Disease Models, Animal
Movement Disorders Antibodies	>3 publications with SYT4 and Movement Disorders
Neurobehavioral Manifestations Antibodies	>3 publications with SYT4 and Neurobehavioral Manifestations
Learning Disorders Antibodies	>2 publications with SYT4 and Learning Disorders
Cardiovascular Diseases Antibodies	>1 publications with SYT4 and Cardiovascular Diseases
Nerve Degeneration Antibodies	>1 publications with SYT4 and Nerve Degeneration
Brain Injuries Antibodies	>1 publications with SYT4 and Brain Injuries
Abnormalities, Drug-Induced Antibodies	>1 publications with SYT4 and Abnormalities, Drug-Induced

Organs/Tissues associated with SYT4 recombinant protein

Organ/Tissue Name	Pubmed Publications
Nerve Antibodies	>38 publications with SYT4 and Nerve
Brain Antibodies	>36 publications with SYT4 and Brain
Pancreas Antibodies	>3 publications with SYT4 and Pancreas
Ganglia Antibodies	>2 publications with SYT4 and Ganglia
Pituitary Gland Antibodies	>2 publications with SYT4 and Pituitary Gland
Embryonic Tissue Antibodies	>2 publications with SYT4 and Embryonic Tissue
Eye Antibodies	>1 publications with SYT4 and Eye
Muscle Antibodies	>1 publications with SYT4 and Muscle
Adrenal Gland Antibodies	>1 publications with SYT4 and Adrenal Gland