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Nescient Helix Loop Helix 1 (NHLH1) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS145950

Description: NHLH1 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 156 amino acids (1-133) and having a molecular mass of 17.0kDa.NHLH1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary… More details

$250 / 0.001 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Nescient Helix Loop Helix 1 (NHLH1), Recombinant Protein
Full Product Name
Recombinant Human Nescient Helix Loop Helix 1
Product Gene Name
Product Synonym Names
NHLH1 Human; Nescient Helix Loop Helix 1 Human Recombinant; Nescient Helix Loop Helix 1; Class A Basic Helix-Loop-Helix Protein 35; Helix-Loop-Helix Protein 1; BHLHA35; NSCL1; HEN1
Sequence
MGSSHHH HHH SSGLVPRGSH MGSMML NSDT MELDLPPTHS ETESGFSDCG GGAGPDGAGP GGPGGGQARG PEPGEPGRKD LQHLSREERR RRRRATAKYR TAHATRERIR VEAFNLAFAE LRKLLPTLPP DKKLSKIEIL RLAICYISYL NHVLDV
Host
E Coli
Form/Format
The NHLH1 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 2mM DTT and 40% glycerol.
Sterile Filtered clear solution.
Purity/Purification
Greater than 85% as determined by SDS-PAGE.
Molecular Weight
14,618 Da
OMIM
162360
3D Structure
ModBase 3D Structure for Q02575

Other Notes

Small volumes of NHLH1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NHLH1 purchase

MBS145950 is a recombinant protein targeting NHLH1. Also known as Recombinant Human Nescient Helix Loop Helix 1. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for NHLH1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
helix-loop-helix protein 1
NCBI Official Synonym Full Names
nescient helix loop helix 1
NCBI Official Symbol
NHLH1
NCBI Official Synonym Symbols
HEN1; NSCL; NSCL1; bHLHa35
UniProt Protein Name
Helix-loop-helix protein 1
UniProt Synonym Protein Names
Class A basic helix-loop-helix protein 35; bHLHa35; Nescient helix loop helix 1; NSCL-1
UniProt Gene Name
NHLH1
UniProt Synonym Gene Names
BHLHA35; HEN1; HEN-1; bHLHa35; NSCL-1
UniProt Entry Name
HEN1_HUMAN
NCBI Protein Information
helix-loop-helix protein 1; HEN-1; NSCL-1; class A basic helix-loop-helix protein 35

NCBI Summary for NHLH1

The helix-loop-helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC (MIM 190080), LYL1 (MIM 151440), E2A (MIM 147141), and SCL (MIM 187040).[supplied by OMIM, Nov 2002]
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UniProt Comments for NHLH1

NHLH1: May serve as DNA-binding protein and may be involved in the control of cell-type determination, possibly within the developing nervous system.

Chromosomal Location of Human Ortholog: 1q22

Cellular Component: nucleus

Molecular Function: protein dimerization activity

Biological Process: central nervous system development; transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; cell differentiation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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